U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Glioblastoma by Gene Expression Profile

MedGen UID:
819942
Concept ID:
C3827194
Neoplastic Process

Definition

Classification of glioblastoma into molecular subtypes as defined by gene expression profiling. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlioblastoma by Gene Expression Profile

Professional guidelines

PubMed

Menyhárt O, Fekete JT, Győrffy B
Carcinogenesis 2021 Jun 21;42(6):804-813. doi: 10.1093/carcin/bgab024. PMID: 33754151Free PMC Article
Bush NA, Butowski N
Curr Oncol Rep 2017 Apr;19(4):26. doi: 10.1007/s11912-017-0585-6. PMID: 28303493
Huse JT, Aldape KD
Clin Cancer Res 2014 Nov 15;20(22):5601-11. doi: 10.1158/1078-0432.CCR-14-0831. PMID: 25398843

Recent clinical studies

Etiology

Zhao S, Wang Q, Ni K, Zhang P, Liu Y, Xie J, Ji W, Cheng C, Zhou Q
Front Immunol 2023;14:1263329. Epub 2023 Aug 31 doi: 10.3389/fimmu.2023.1263329. PMID: 37727789Free PMC Article
Zhang B, Xie L, Liu J, Liu A, He M
Front Immunol 2023;14:1082974. Epub 2023 Feb 6 doi: 10.3389/fimmu.2023.1082974. PMID: 36814929Free PMC Article
Zhou Y, Xiao D, Jiang X, Nie C
J Transl Med 2023 Jan 16;21(1):28. doi: 10.1186/s12967-023-03883-4. PMID: 36647156Free PMC Article
Shern JF, Selfe J, Izquierdo E, Patidar R, Chou HC, Song YK, Yohe ME, Sindiri S, Wei J, Wen X, Rudzinski ER, Barkauskas DA, Lo T, Hall D, Linardic CM, Hughes D, Jamal S, Jenney M, Chisholm J, Brown R, Jones K, Hicks B, Angelini P, George S, Chesler L, Hubank M, Kelsey A, Gatz SA, Skapek SX, Hawkins DS, Shipley JM, Khan J
J Clin Oncol 2021 Sep 10;39(26):2859-2871. Epub 2021 Jun 24 doi: 10.1200/JCO.20.03060. PMID: 34166060Free PMC Article
Wu YM, Su F, Kalyana-Sundaram S, Khazanov N, Ateeq B, Cao X, Lonigro RJ, Vats P, Wang R, Lin SF, Cheng AJ, Kunju LP, Siddiqui J, Tomlins SA, Wyngaard P, Sadis S, Roychowdhury S, Hussain MH, Feng FY, Zalupski MM, Talpaz M, Pienta KJ, Rhodes DR, Robinson DR, Chinnaiyan AM
Cancer Discov 2013 Jun;3(6):636-47. Epub 2013 Apr 4 doi: 10.1158/2159-8290.CD-13-0050. PMID: 23558953Free PMC Article

Diagnosis

Zhang B, Xie L, Liu J, Liu A, He M
Front Immunol 2023;14:1082974. Epub 2023 Feb 6 doi: 10.3389/fimmu.2023.1082974. PMID: 36814929Free PMC Article
Geraldo LH, Xu Y, Jacob L, Pibouin-Fragner L, Rao R, Maissa N, Verreault M, Lemaire N, Knosp C, Lesaffre C, Daubon T, Dejaegher J, Solie L, Rudewicz J, Viel T, Tavitian B, De Vleeschouwer S, Sanson M, Bikfalvi A, Idbaih A, Lu QR, Lima FR, Thomas JL, Eichmann A, Mathivet T
J Clin Invest 2021 Aug 16;131(16) doi: 10.1172/JCI141083. PMID: 34181595Free PMC Article
Shern JF, Selfe J, Izquierdo E, Patidar R, Chou HC, Song YK, Yohe ME, Sindiri S, Wei J, Wen X, Rudzinski ER, Barkauskas DA, Lo T, Hall D, Linardic CM, Hughes D, Jamal S, Jenney M, Chisholm J, Brown R, Jones K, Hicks B, Angelini P, George S, Chesler L, Hubank M, Kelsey A, Gatz SA, Skapek SX, Hawkins DS, Shipley JM, Khan J
J Clin Oncol 2021 Sep 10;39(26):2859-2871. Epub 2021 Jun 24 doi: 10.1200/JCO.20.03060. PMID: 34166060Free PMC Article
Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW
Cancer Cell 2017 Jul 10;32(1):42-56.e6. doi: 10.1016/j.ccell.2017.06.003. PMID: 28697342Free PMC Article
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Therapy

Wang R, Peng L, Xiao Y, Zhou Q, Wang Z, Tang L, Xiao H, Yang K, Liu H, Li L
Cancer Gene Ther 2023 May;30(5):716-726. Epub 2023 Jan 4 doi: 10.1038/s41417-022-00582-y. PMID: 36599974Free PMC Article
Xuan W, Hsu WH, Khan F, Dunterman M, Pang L, Wainwright DA, Ahmed AU, Heimberger AB, Lesniak MS, Chen P
Cancer Immunol Res 2022 Jun 3;10(6):770-784. doi: 10.1158/2326-6066.CIR-21-0559. PMID: 35413115Free PMC Article
Barrette AM, Ronk H, Joshi T, Mussa Z, Mehrotra M, Bouras A, Nudelman G, Jesu Raj JG, Bozec D, Lam W, Houldsworth J, Yong R, Zaslavsky E, Hadjipanayis CG, Birtwistle MR, Tsankova NM
Neuro Oncol 2022 May 4;24(5):694-707. doi: 10.1093/neuonc/noab244. PMID: 34657158Free PMC Article
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606. Epub 2021 Feb 25 doi: 10.1080/15548627.2021.1885203. PMID: 33629929Free PMC Article
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Prognosis

Zhang B, Xie L, Liu J, Liu A, He M
Front Immunol 2023;14:1082974. Epub 2023 Feb 6 doi: 10.3389/fimmu.2023.1082974. PMID: 36814929Free PMC Article
Torrini C, Nguyen TTT, Shu C, Mela A, Humala N, Mahajan A, Seeley EH, Zhang G, Westhoff MA, Karpel-Massler G, Bruce JN, Canoll P, Siegelin MD
Mol Cell 2022 Aug 18;82(16):3061-3076.e6. Epub 2022 Aug 9 doi: 10.1016/j.molcel.2022.06.030. PMID: 35948010Free PMC Article
Xuan W, Hsu WH, Khan F, Dunterman M, Pang L, Wainwright DA, Ahmed AU, Heimberger AB, Lesniak MS, Chen P
Cancer Immunol Res 2022 Jun 3;10(6):770-784. doi: 10.1158/2326-6066.CIR-21-0559. PMID: 35413115Free PMC Article
Di W, Fan W, Wu F, Shi Z, Wang Z, Yu M, Zhai Y, Chang Y, Pan C, Li G, Kahlert UD, Zhang W
Cancer Sci 2022 Feb;113(2):756-769. Epub 2021 Dec 24 doi: 10.1111/cas.15236. PMID: 34881489Free PMC Article
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE
Science 2014 Jun 20;344(6190):1396-401. Epub 2014 Jun 12 doi: 10.1126/science.1254257. PMID: 24925914Free PMC Article

Clinical prediction guides

Hoogstrate Y, Draaisma K, Ghisai SA, van Hijfte L, Barin N, de Heer I, Coppieters W, van den Bosch TPP, Bolleboom A, Gao Z, Vincent AJPE, Karim L, Deckers M, Taphoorn MJB, Kerkhof M, Weyerbrock A, Sanson M, Hoeben A, Lukacova S, Lombardi G, Leenstra S, Hanse M, Fleischeuer REM, Watts C, Angelopoulos N, Gorlia T, Golfinopoulos V, Bours V, van den Bent MJ, Robe PA, French PJ
Cancer Cell 2023 Apr 10;41(4):678-692.e7. Epub 2023 Mar 9 doi: 10.1016/j.ccell.2023.02.019. PMID: 36898379
Jain S, Rick JW, Joshi RS, Beniwal A, Spatz J, Gill S, Chang AC, Choudhary N, Nguyen AT, Sudhir S, Chalif EJ, Chen JS, Chandra A, Haddad AF, Wadhwa H, Shah SS, Choi S, Hayes JL, Wang L, Yagnik G, Costello JF, Diaz A, Heiland DH, Aghi MK
J Clin Invest 2023 Mar 1;133(5) doi: 10.1172/JCI147087. PMID: 36856115Free PMC Article
Zhang B, Xie L, Liu J, Liu A, He M
Front Immunol 2023;14:1082974. Epub 2023 Feb 6 doi: 10.3389/fimmu.2023.1082974. PMID: 36814929Free PMC Article
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54. Epub 2014 Dec 15 doi: 10.1038/onc.2014.406. PMID: 25500544Free PMC Article
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE
Science 2014 Jun 20;344(6190):1396-401. Epub 2014 Jun 12 doi: 10.1126/science.1254257. PMID: 24925914Free PMC Article

Recent systematic reviews

Phon BWS, Kamarudin MNA, Bhuvanendran S, Radhakrishnan AK
Biomed Pharmacother 2022 Jan;145:112396. Epub 2021 Nov 11 doi: 10.1016/j.biopha.2021.112396. PMID: 34775238
Chuffa LGA, Carvalho RF, Justulin LA, Cury SS, Seiva FRF, Jardim-Perassi BV, Zuccari DAPC, Reiter RJ
J Pineal Res 2020 Nov;69(4):e12693. Epub 2020 Sep 19 doi: 10.1111/jpi.12693. PMID: 32910542
Iser IC, Pereira MB, Lenz G, Wink MR
Med Res Rev 2017 Mar;37(2):271-313. Epub 2016 Sep 12 doi: 10.1002/med.21408. PMID: 27617697

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...