From HPO
Chest pain- MedGen UID:
- 2992
- •Concept ID:
- C0008031
- •
- Sign or Symptom
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the chest.
Hypercalciuria- MedGen UID:
- 43775
- •Concept ID:
- C0020438
- •
- Finding
Abnormally high level of calcium in the urine.
Clubbing- MedGen UID:
- 57692
- •Concept ID:
- C0149651
- •
- Anatomical Abnormality
Broadening of the soft tissues (non-edematous swelling of soft tissues) of the digital tips in all dimensions associated with an increased longitudinal and lateral curvature of the nails.
Pericardial effusion- MedGen UID:
- 10653
- •Concept ID:
- C0031039
- •
- Disease or Syndrome
Accumulation of fluid within the pericardium.
Pulmonary arterial hypertension- MedGen UID:
- 425404
- •Concept ID:
- C2973725
- •
- Disease or Syndrome
Pulmonary hypertension is defined mean pulmonary artery pressure of 25mmHg or more and pulmonary capillary wedge pressure of 15mmHg or less when measured by right heart catheterisation at rest and in a supine position.
Weight loss- MedGen UID:
- 853198
- •Concept ID:
- C1262477
- •
- Finding
Reduction of total body weight.
Hepatomegaly- MedGen UID:
- 42428
- •Concept ID:
- C0019209
- •
- Finding
Abnormally increased size of the liver.
Inflammation of the large intestine- MedGen UID:
- 662273
- •Concept ID:
- C0578878
- •
- Disease or Syndrome
Inflammation, or an inflammatory state in the large intestine.
Anorexia- MedGen UID:
- 315
- •Concept ID:
- C0003123
- •
- Disease or Syndrome
Anorexia, or the loss of appetite for food, is a medical condition.
Photophobia- MedGen UID:
- 43220
- •Concept ID:
- C0085636
- •
- Sign or Symptom
Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
Pancytopenia- MedGen UID:
- 18281
- •Concept ID:
- C0030312
- •
- Disease or Syndrome
An abnormal reduction in numbers of all blood cell types (red blood cells, white blood cells, and platelets).
Arthritis- MedGen UID:
- 2043
- •Concept ID:
- C0003864
- •
- Disease or Syndrome
Inflammation of a joint.
Bone cyst- MedGen UID:
- 2696
- •Concept ID:
- C0005937
- •
- Anatomical Abnormality
A fluid filled cavity that develops with a bone.
Bronchiectasis- MedGen UID:
- 14234
- •Concept ID:
- C0006267
- •
- Disease or Syndrome
Persistent abnormal dilatation of the bronchi owing to localized and irreversible destruction and widening of the large airways.
Cough- MedGen UID:
- 41325
- •Concept ID:
- C0010200
- •
- Sign or Symptom
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation.
Dyspnea- MedGen UID:
- 3938
- •Concept ID:
- C0013404
- •
- Sign or Symptom
Difficult or labored breathing. Dyspnea is a subjective feeling only the patient can rate, e.g., on a Borg scale.
Hemoptysis- MedGen UID:
- 5502
- •Concept ID:
- C0019079
- •
- Sign or Symptom
Coughing up (expectoration) of blood or blood-streaked sputum from the larynx, trachea, bronchi, or lungs.
Pleural effusion- MedGen UID:
- 10805
- •Concept ID:
- C0032227
- •
- Disease or Syndrome
The presence of an excessive amount of fluid in the pleural cavity.
Emphysema- MedGen UID:
- 18764
- •Concept ID:
- C0034067
- •
- Disease or Syndrome
A subcategory of chronic obstructive pulmonary disease (COPD). It occurs in people who smoke and suffer from chronic bronchitis. It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing.
Pulmonary fibrosis- MedGen UID:
- 11028
- •Concept ID:
- C0034069
- •
- Disease or Syndrome
Replacement of normal lung tissues by fibroblasts and collagen.
Pulmonary infiltrates- MedGen UID:
- 116009
- •Concept ID:
- C0235896
- •
- Finding
A finding indicating the presence of an inflammatory or neoplastic cellular infiltrate in the lung parenchyma.
Hypoxemia- MedGen UID:
- 152145
- •Concept ID:
- C0700292
- •
- Finding
An abnormally low level of blood oxygen.
Restrictive ventilatory defect- MedGen UID:
- 478856
- •Concept ID:
- C3277226
- •
- Finding
A functional defect characterized by reduced total lung capacity (TLC) not associated with abnormalities of expiratory airflow or airway resistance. Spirometrically, a restrictive defect is defined as FEV1 (forced expiratory volume in 1 second) and FVC (forced vital capacity) less than 80 per cent. Restrictive lung disease may be caused by alterations in lung parenchyma or because of a disease of the pleura, chest wall, or neuromuscular apparatus.
Elevated bronchoalveolar lavage fluid lymphocyte proportion- MedGen UID:
- 1713125
- •Concept ID:
- C5397968
- •
- Finding
Usually, Lymphoycytes make up less than 15% of all cells found in the bronchoalveloar lavage fluid. This elevated cell proportion can be induced by virus or drugs, or is associated with specific diseases.
Abnormal pulmonary interstitial morphology- MedGen UID:
- 1788738
- •Concept ID:
- C5441745
- •
- Anatomical Abnormality
Abnormality of the lung parenchyma extending to the pulmonary interstitium and leading to diffuse pulmonary fibrosis.
Iridocyclitis- MedGen UID:
- 43961
- •Concept ID:
- C0022073
- •
- Disease or Syndrome
A type of anterior uveitis, in which there is Inflammation of the iris and the ciliary body.
Splenomegaly- MedGen UID:
- 52469
- •Concept ID:
- C0038002
- •
- Finding
Abnormal increased size of the spleen.
Uveitis- MedGen UID:
- 52961
- •Concept ID:
- C0042164
- •
- Disease or Syndrome
Inflammation of one or all portions of the uveal tract.
Generalized lymphadenopathy- MedGen UID:
- 96909
- •Concept ID:
- C0476486
- •
- Finding
A generalized form of lymphadenopathy.
Abnormality of T cell physiology- MedGen UID:
- 868761
- •Concept ID:
- C4023166
- •
- Pathologic Function
A functional anomaly of T cells.
Increased circulating antibody concentration- MedGen UID:
- 1713383
- •Concept ID:
- C5397581
- •
- Finding
An increased level of gamma globulin (immunoglobulin) in the blood.
Fever- MedGen UID:
- 5169
- •Concept ID:
- C0015967
- •
- Sign or Symptom
Body temperature elevated above the normal range.
Elevated erythrocyte sedimentation rate- MedGen UID:
- 57727
- •Concept ID:
- C0151632
- •
- Finding
An increased erythrocyte sedimentation rate (ESR). The ESR is a test that measures the distance that erythrocytes have fallen after one hour in a vertical column of anticoagulated blood under the influence of gravity. The ESR is a nonspecific finding. An elevation may indicate inflammation or may be caused by any condition that elevates fibrinogen.
Abnormal salivary gland morphology- MedGen UID:
- 892384
- •Concept ID:
- C0149772
- •
- Anatomical Abnormality
Any abnormality of the salivary glands, the exocrine glands that produce saliva.
Enlarged lacrimal glands- MedGen UID:
- 401142
- •Concept ID:
- C1867030
- •
- Finding
Abnormally big lacrimal glands.
Mediastinal lymphadenopathy- MedGen UID:
- 451062
- •Concept ID:
- C0520743
- •
- Disease or Syndrome
Swelling of lymph nodes within the mediastinum, the central compartment of the thoracic cavities that contains the heart and the great vessels, the esophagus, and trachea and other structures including lymph nodes.
Chorioretinitis- MedGen UID:
- 942
- •Concept ID:
- C0008513
- •
- Disease or Syndrome
An inflammation of the choroid and retina.
Glaucoma- MedGen UID:
- 42224
- •Concept ID:
- C0017601
- •
- Disease or Syndrome
Glaucoma refers loss of retinal ganglion cells in a characteristic pattern of optic neuropathy usually associated with increased intraocular pressure.
Epiphora- MedGen UID:
- 57518
- •Concept ID:
- C0152227
- •
- Disease or Syndrome
Abnormally increased lacrimation, that is, excessive tearing (watering eye).
Blurred vision- MedGen UID:
- 91020
- •Concept ID:
- C0344232
- •
- Finding
Lack of sharpness of vision resulting in the inability to see fine detail.
Optic neuropathy- MedGen UID:
- 854546
- •Concept ID:
- C3887709
- •
- Disease or Syndrome
Disorder of the optic nerve.
- Abnormality of blood and blood-forming tissues
- Abnormality of head or neck
- Abnormality of limbs
- Abnormality of metabolism/homeostasis
- Abnormality of the cardiovascular system
- Abnormality of the digestive system
- Abnormality of the eye
- Abnormality of the genitourinary system
- Abnormality of the immune system
- Abnormality of the musculoskeletal system
- Abnormality of the nervous system
- Abnormality of the respiratory system
- Abnormality of the thoracic cavity
- Constitutional symptom
- Growth abnormality