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National Collaborating Centre for Mental Health (UK). Challenging Behaviour and Learning Disabilities: Prevention and Interventions for People with Learning Disabilities Whose Behaviour Challenges. London: National Institute for Health and Care Excellence (NICE); 2015 May. (NICE Guideline, No. 11.)

Cover of Challenging Behaviour and Learning Disabilities

Challenging Behaviour and Learning Disabilities: Prevention and Interventions for People with Learning Disabilities Whose Behaviour Challenges.

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Appendix OClinical evidence – GRADE evidence profiles for all studies

O.1. Risk markers associated with the development of behaviour that challenges

O.3. Interventions aimed at the prevention of behaviour that challenges

O.3.3. EIBI versus parent training

Table O.12. EIBI (UCLA model) versus parent training (PDF, 260K)

O.4. Interventions aimed at reducing health risks and increasing understanding of physical illness in relation to the prevention or management of behaviour that challenges

O.4.1. Hand-held health record versus treatment as usual

Table O.15. Advocacy Skills Kit Diary or Personal Health Profile versus treatment as usual (PDF, 232K)

O.4.2. Annual health check versus treatment as usual

Table O.16. Comprehensive Health Assessment Program versus treatment as usual (PDF, 229K)

O.4.3. Annual health check versus hand-held health record

Table O.17. Comprehensive Health Assessment Program versus Advocacy Skills Kit Diary (PDF, 210K)

O.4.4. Annual health check and hand-held health record versus treatment as usual

Table O.18. Comprehensive Health Assessment Program and Advocacy Skills Kit Diary versus treatment as usual (PDF, 203K)

O.5. Environmental change interventions aimed at reducing and managing behaviour that challenges

O.5.1. Sensory intervention versus any control

Table O.19. Multisensory room or vibroacoustic chair versus any control (PDF, 284K)

O.5.2. Structured activity versus unstructured activity

Table O.20. Special Olympics Sports Skill Instructional Program versus free play (PDF, 248K)

O.6. Parent training interventions aimed at reducing and managing behaviour that challenges

O.6.1. Parent training versus any control

Table O.21. Parent training versus any control (PDF, 270K)

O.6.2. Individual parent training versus group parent training

Table O.22. Individual parent training versus group parent training (PDF, 257K)

O.6.3. Parent training plus optimism training versus parent training alone

Table O.23. Parent training plus optimism training versus parent training alone (PDF, 252K)

O.6.4. Enhanced parent training versus standard parent training

Table O.24. Enhanced parent training versus standard parent training (PDF, 275K)

O.7. Psychosocial interventions aimed at reducing and managing behaviour that challenges

O.7.1. Cognitive behavioural interventions versus any control

Table O.25. Cognitive behaviour interventions versus any control (PDF, 273K)

O.7.2. Behavioural therapy versus any control

Table O.26. Behavioural therapy versus any control (PDF, 244K)

O.8. Sleep interventions aimed at reducing and managing behaviour that challenges

O.8.1. Sleep interventions versus any control

Table O.27. Sleep interventions versus any control (PDF, 289K)

O.8.2. Face-to-face sleep intervention versus booklet only

Table O.28. Face-to-face sleep intervention versus booklet only (PDF, 240K)

O.9. Pharmacological interventions aimed at reducing and managing behaviour that challenges

O.9.1. Risperidone versus placebo in children and young people

Table O.29. Risperidone versus placebo in children and young people (PDF, 291K)

O.9.2. Withdrawal of risperidone versus continuation of risperidone in children and young people

Table O.30. Withdrawal of risperidone versus continuation of risperidone in children and young people (PDF, 240K)

O.9.3. Aripiprazole versus placebo in children and young people

Table O.31. Aripiprazole versus placebo in children and young people (PDF, 273K)

O.9.4. Aripiprazole versus risperidone in children and young people

Table O.32. Aripiprazole versus risperidone in children and young people (PDF, 255K)

O.9.5. Withdrawal of aripiprazole versus continuation of aripiprazole in children and young people

Table O.33. Withdrawal of aripiprazole versus continuation of aripiprazole in children and young people (PDF, 256K)

O.9.6. Olanzapine versus haloperidol in children and young people

Table O.34. Olanzapine versus haloperidol in children and young people (PDF, 254K)

O.9.7. Topiramate (plus risperidone) versus placebo (plus risperidone) in children and young people

Table O.35. Topiramate (plus risperidone) versus placebo (plus risperidone) in children and young people (PDF, 254K)

O.9.8. Valproate versus placebo in children and young people

Table O.36. Topiramate (plus risperidone) versus placebo (plus risperidone) in children and young people (PDF, 269K)

O.9.9. N-acetylcysteine versus placebo in children and young people

Table O.37. N-acetylcysteine versus placebo in children and young people (PDF, 253K)

O.9.10. Ginkgo biloba (plus risperidone) versus placebo (plus risperidone) in children and young people

Table O.38. Ginkgo biloba (plus risperidone) versus placebo (plus risperidone) in children and young people (PDF, 251K)

O.9.11. Omega-3 versus placebo in children and young people

Table O.39. Omega-3 versus placebo in children and young people (PDF, 251K)

O.9.12. Piracetam (plus risperidone) versus placebo (plus risperidone) in children and young people

Table O.40. Piracetam (plus risperidone) versus placebo (plus risperidone) in children and young people (PDF, 242K)

O.9.13. Risperidone versus placebo in adults

Table O.41. Risperidone versus placebo in adults (PDF, 277K)

O.9.14. Haloperidol versus placebo in adults

Table O.42. Haloperidol versus placebo in adults (PDF, 214K)

O.9.15. Risperidone versus haloperidol in adults

Table O.43. Risperidone versus haloperidol in adults (PDF, 271K)

O.9.16. Olanzapine versus risperidone in adults

Table O.44. Olanzapine versus risperidone in adults (PDF, 256K)

O.9.17. Lithium versus placebo in adults

Table O.45. Lithium versus placebo in adults (PDF, 193K)

O.9.18. Withdrawal of zuclopenthixol versus continuation of zuclopenthixol in adults

Table O.46. Withdrawal of zuclopenthixol versus continuation of zuclopenthixol in adults (PDF, 273K)

O.9.19. Melatonin versus placebo in children and young people

Table O.47. Melatonin versus placebo in children and young people (PDF, 347K)

O.9.20. Melatonin versus cognitive behavioural therapy in children and young people

Table O.48. Melatonin versus cognitive behavioural therapy in children and young people (PDF, 263K)

O.10. Interventions aimed at improving the health and well-being of carers of people with learning disabilities

O.10.1. Cognitive behavioural interventions for family carers versus any control

Table O.49. Cognitive behavioural interventions for family carers versus any control (PDF, 282K)

O.10.2. Psychoeducational interventions for family carers versus any control

Table O.50. Psychoeducational interventions for family carers versus any control (PDF, 250K)

O.10.3. Support interventions for family carers versus any control

Table O.51. Parent advisor scheme versus treatment as usual (PDF, 241K)

O.10.4. Mindfulness interventions for paid carers versus any control

Table O.52. Mindfulness interventions for paid carers versus any control (PDF, 271K)

Copyright © The British Psychological Society & The Royal College of Psychiatrists, 2015.
Bookshelf ID: NBK355394

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