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Select item 29561.

Analysis of subcutaneous abdominal fat and hypothalami of male Sprague-Dawleys that lost or regained weight after Roux-en-Y gastric bypass (RYGB) surgery. Obesity induced by diet prior to RYBG. Results provide insight into the mechanisms contributing to successful weight loss following RYBG.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 3 disease state, 3 other, 2 protocol, 2 tissue sets

Platform:: GPL1355
Series:: GSE8314
18 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2956

ID:: 2956

Select item 56042.

Fibroblast growth factor 2 effect on lens epithelia explant cultures: time course

Analysis of lens explant cultures grown overnight in the presence of 5 ng/mL FGF2 to promote proliferation and survival, then treated with 100 ng/mL FGF2 for up to 24hr to induce differentiation. Results provide insight into the molecular basis of FGF2-induced lens fiber cell differentiation.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 growth protocol, 5 time sets

Platform:: GPL1355
Series:: GSE50604
10 Samples

Download data: CEL

DataSet

Accession:: GDS5604

ID:: 5604

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 53903.

Whey protein hydrolysate diet effect on exercised epitrochlearis muscle

Analysis of epitrochlearis muscle from males exercised for 2hr then fed a whey protein hydrolysate (WPH) diet or a control diet with an identical amino acid composition (AAM). Results provide insight into the molecular basis of the greater post-exercise muscle protein synthesis in the WPH group.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL1355
Series:: GSE49486
8 Samples

Download data: CEL

DataSet

Accession:: GDS5390

ID:: 5390

Select item 52834.

Hexahydro-1,3,5-trinitro-1,3,5-triazine effect on the liver: dose response and time course

Analysis of livers of males for up to 48 hours after treatment with a single, oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the liver.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:: GPL1355
Series:: GSE12196
24 Samples

Download data: CEL

DataSet

Accession:: GDS5283

ID:: 5283

Select item 52825.

Hexahydro-1,3,5-trinitro-1,3,5-triazine effect on the brain: dose response and time course

Analysis of cerebral cortices of males for up to 48 hours after treatment with an oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the brain.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:: GPL1355
Series:: GSE12196
24 Samples

Download data: CEL

DataSet

Accession:: GDS5282

ID:: 5282

Select item 52576.

Calyx of Held synaptic development: globular bushy cells

Analysis of calyx of Held globular bushy cells at different maturation stages: P3, P8 and P21. Calyx of Held presynaptic terminals in the auditory brainstem develop into axosomatic synapses. Results provide insight into mechanisms underlying development of mammalian synaptic structure and function.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 3 cell type, 3 development stage sets

Platform:: GPL1355
Series:: GSE49599
20 Samples

Download data: CEL

DataSet

Accession:: GDS5257

ID:: 5257

Select item 52527.

Bacterial lipopolysaccharide endotoxin stimulation effect on hepatic stellate cells: time course (experiment 1)

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1, 3, 6, 12, 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent, 5 time sets

Platform:: GPL1355
Series:: GSE49980
11 Samples

Download data: CEL

DataSet

Accession:: GDS5252

ID:: 5252

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 52518.

Bacterial lipopolysaccharide endotoxin stimulation effect on hepatic stellate cells: time course (experiment 2)

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1 and 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent, 2 time sets

Platform:: GPL1355
Series:: GSE49980
8 Samples

Download data: CEL

DataSet

Accession:: GDS5251

ID:: 5251

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 52469.

Oligodendroglial cell model of multiple system atrophy: time course

Analysis of oligodendroglia stably expressing α-synuclein and transiently expressing p25α for up to 16 hrs. Coexpression of α -synuclein and p25α causes a degenerative phenotype modeling multiple system atrophy (MSA). Results provide insight into the molecular basis of MSA pathogenesis.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 protocol, 3 time sets

Platform:: GPL1355
Series:: GSE51781
12 Samples

Download data: CEL

DataSet

Accession:: GDS5246

ID:: 5246

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 521510.

Molecular hydrogen-saturated water consumption effect on the liver

Analysis of livers of Sprague-Dawley animals following consumption of water containing 0.7 mM dissolved molecular hydrogen for 4 weeks. Molecular hydrogen is an antioxidant. Results provide insight into the molecular response of the liver to hydrogen saturated water.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL1355
Series:: GSE26363
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5215

ID:: 5215

Select item 506311.

Conventional cigarette or modified-risk tobacco product smoke effect on lung bronchial epithelium: dose response

Analysis of left lung bronchi from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:: GPL1355
Series:: GSE50254
25 Samples

Download data: CEL

DataSet

Accession:: GDS5063

ID:: 5063

Select item 506212.

Conventional cigarette or modified-risk tobacco product smoke effect on lung parenchyma: dose response

Analysis of left lung parenchyma from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:: GPL1355
Series:: GSE50254
25 Samples

Download data: CEL

DataSet

Accession:: GDS5062

ID:: 5062

Select item 506113.

Conventional cigarette or modified-risk tobacco product smoke effect on nasal respiratory epithelium: dose response

Analysis of nasal epithelia from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:: GPL1355
Series:: GSE50254
25 Samples

Download data: CEL

DataSet

Accession:: GDS5061

ID:: 5061

Select item 503414.

Polybrominated diphenyl ether effect on the liver

Analysis of livers collected from postnatal day (PND) 22 and 13-week-old Wistar/Han rats exposed in utero to polybrominated diphenyl ether (PBDE) and directly dosed with PBDE. PBDEs are flame retardants. Results provide insight into the molecular basis of PBDE toxicities.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 age, 2 agent, 2 gender sets

Platform:: GPL1355
Series:: GSE32156
30 Samples

Download data: CEL

DataSet

Accession:: GDS5034

ID:: 5034

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 503315.

Diencephalon response to short-term dietary zinc deficiency followed by zinc recovery

Analysis of diencephalon from Sprague-Dawley males fed a zinc-deficient diet for 10 days then a control diet for 6 days. The zinc recovery restored food intake behaviors and salt preferences. Results provide insight into the molecular effects of short-term zinc deficiency and recovery on the brain.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL1355
Series:: GSE31430
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5033

ID:: 5033

Select item 503216.

Early postnatal nerve tissue response to acrylamide: sciatic nerve

Analysis of sciatic nerve from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL1355
Series:: GSE29004
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5032

ID:: 5032

Select item 503117.

Early postnatal nerve tissue response to acrylamide: spinal cord

Analysis of spinal cord from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL1355
Series:: GSE29004
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5031

ID:: 5031

Select item 495418.

Cobalt effect on liver cell line MH1C1: dose response

Analysis of MH1C1 liver cells exposed to 160 or 310 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 agent, 3 dose sets

Platform:: GPL1355
Series:: GSE51207
12 Samples

Download data: CEL

DataSet

Accession:: GDS4954

ID:: 4954

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 495319.

Cobalt effect on liver cell line H4IIEC3: dose response

Analysis of H4IIEC3 liver cells exposed to 29 or 62 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 agent, 3 dose sets

Platform:: GPL1355
Series:: GSE51207
12 Samples

Download data: CEL

DataSet

Accession:: GDS4953

ID:: 4953

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 494020.

Hippocampus response to acetylcholinesterase inhibitor soman: time course

Analysis of hippocampi of Sprauge-Dawley males for up to 168 hours following exposure to the acetylcholinesterase inhibitor soman. Soman is a potent neurotoxicant. Results provide insight into the molecular pathogenesis of soman-induced neurodegeneration.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 3 agent, 10 time sets

Platform:: GPL1355
Series:: GSE13428
38 Samples

Download data: CEL

DataSet

Accession:: GDS4940

ID:: 4940

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