Similar studies for GEO DataSets (Select 1636) - GEO DataSets

Select item 16361.

Expression profiling of S288C cells treated with 50 ppm patulin for 2 hours. Patulin is a toxic and colorless crystalline antibiotic produced by several molds that can grow naturally on fruits and vegetables. Results provide insight into the mechanisms underlying the cytotoxicity of patulin.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, log2 ratio, 2 protocol sets

Platform:: GPL1945
Series:: GSE2923
6 Samples

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DataSet

Accession:: GDS1636

ID:: 1636

Select item 2000029232.

50 ppm Patulin treatment for 2 h

(Submitter supplied) Patulin, 4-hydroxy-4H-furo[3,2c]pyran-2(6H)-one, is one of the most popular and characterized mycotoxin observed in agricultural products. However the mechnisims of toxicity by this chemical is not well understood. Thus, we characterized the cytotoxicity of patulin using yeast transcriptome systems. The expression profile of mRNA after exposure yeast cells to patulin was similar to those after the treatment by antifungal agricultural chemicals such as thiuram, maneb, and zeneb. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Dataset:: GDS1636
Platform:: GPL1945
6 Samples

Download data

Series

Accession:: GSE2923

ID:: 200002923

Select item 2000061183.

300 ppm Citrinin treatment for 2 h

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platforms:: GPL4399 GPL1945
15 Samples

Download data: GPR, TIFF, TXT

Series

Accession:: GSE6118

ID:: 200006118

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000061114.

300 ppm Citrinin treatment for 2 h (GPL1945)

(Submitter supplied) The availability of yeast DNA microarrays provides the possibility of monitoring gene expression levels as a function to toxin exposure, and consequently as a means of determining mechanisms of toxicity. This system possesses the benefit of the essential volume of yeast cultures, the high reproducibility of expression profiles, and the massive functional information. Because small amount of biological sample cultures are required for this analysis, toxicity test for rare chemical such as mycotoxins which is a natural compound and difficult to be artificially synthesized. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL1945
6 Samples

Download data: GPR, TIFF

Series

Accession:: GSE6111

ID:: 200006111

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000061015.

300 ppm Citrinin treatment for 2 h (GPL4399)

(Submitter supplied) The availability of yeast DNA microarrays provides the possibility of monitoring gene expression levels as a function to toxin exposure, and consequently as a means of determining mechanisms of toxicity. This system possesses the benefit of the essential volume of yeast cultures, the high reproducibility of expression profiles, and the massive functional information. Because small amount of biological sample cultures are required for this analysis, toxicity test for rare chemical such as mycotoxins which is a natural compound and difficult to be artificially synthesized. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4399
9 Samples

Download data: TIFF, TXT

Series

Accession:: GSE6101

ID:: 200006101

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000118566.

Global transcriptional profiling of Saccharomyces cerevisiae treated with allicin

(Submitter supplied) We employed CapitalBio Corporation to investigate the global transcriptional profiling of Saccharomyces cerevisiae treated with allicin.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL6010
3 Samples

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Series

Accession:: GSE11856

ID:: 200011856

Select item 2000261717.

Yeast Genomic Expression Patterns in Response to Patulin and Ascorbic acid

(Submitter supplied) The assessment of toxicity about patulin using yeast gene expression comparison analysis. Yeast BY4743 derivative SOD1 mutant was used for this study. Ascorbic acid was used to evaluate the anti-toxic effect to patulin. Keywords: stress response

Organism:: Saccharomyces cerevisiae; Schizosaccharomyces pombe

Type:: Expression profiling by array

Platform:: GPL2529
12 Samples

Download data: CEL

Series

Accession:: GSE26171

ID:: 200026171

Select item 2000022248.

Experimental condition

(Submitter supplied) BY4730 cultures were exposed to medium containing dilutions of test agent (Cisplatin (Cis), 600mg/mL; Methylmethane sulfonate (MMS), 0.12% v/v; Bleomycin (Bleo), 0.15U/mL; NaCl, 10mg/mL; ethanol, 15% v/v) for 120 min. Control cultures were either mock-treated with the solvent, DMSO (for comparison to Cis, MMS, Bleo) or maintained in media (for comparison to ethanol and NaCl) for 120 mins. Sample preparation and processing procedures were performed according the Affymetrix Genechipâ Expression Analysis Technical Manual (Affymetrix, Santa Clara, CA). more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Dataset:: GDS1299
Platform:: GPL90
24 Samples

Download data

Series

Accession:: GSE2224

ID:: 200002224

Select item 12999.

Genotoxic stress

Analysis of BY4730 cells treated with DNA-reactive compounds cisplatin, methyl methanesulfonate (MMS), and bleomycin to induce genotoxic stress. Effect of genotoxic compounds compared to cytotoxic compounds, NaCl and ethanol. Results identify an expression signature unique to genotoxic stress.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 6 agent sets

Platform:: GPL90
Series:: GSE2224
24 Samples

Download data

DataSet

Accession:: GDS1299

ID:: 1299

Select item 20000612910.

Arsenate stress response: Saccharomyces cerevisiae

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
30 Samples

Download data: GPR, IMAGENE

Series

Accession:: GSE6129

ID:: 200006129

Select item 20000607211.

0.2 mM As(III) stressed met4 deletion mutant vs 0.2 mM As(III) stressed wild-type after 1 hour

(Submitter supplied) Arsenic is ubiquitously present in nature and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
6 Samples

Download data: IMAGENE

Series

Accession:: GSE6072

ID:: 200006072

Select item 20000607112.

1.0 mM As(III) stressed yap1 deletion mutant vs 1.0 mM As(III) stressed wild-type after 1 hour

(Submitter supplied) volved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
3 Samples

Download data: GPR

Series

Accession:: GSE6071

ID:: 200006071

Select item 20000607013.

0.2 mM As(III) stressed yap1 deletion mutant vs 0.2 mM As(III) stressed wild-type after 1 hour

(Submitter supplied) Arsenic is ubiquitously present in nature and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
3 Samples

Download data: IMAGENE

Series

Accession:: GSE6070

ID:: 200006070

Select item 20000606814.

Time Course 1.0 mM As(III)

(Submitter supplied) Arsenic is ubiquitously present in nature and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
15 Samples

Download data: GPR, IMAGENE

Series

Accession:: GSE6068

ID:: 200006068

Select item 20000606715.

0.2 mM As(III) stressed wild-type vs (non-stressed) wild-type after 1 hour

(Submitter supplied) Arsenic is ubiquitously present in nature and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
3 Samples

Download data: IMAGENE

Series

Accession:: GSE6067

ID:: 200006067

Select item 20000606616.

1.0 mM As(III) stressed wild-type vs (non-stressed) wild-type after 1 hour

(Submitter supplied) Arsenic is ubiquitously present in nature and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative and kinetic transcriptome, proteome and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis, arsenic detoxification, oxidative stress defense, redox maintenance and proteolytic activity. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL4462
6 Samples

Download data: GPR

Series

Accession:: GSE6066

ID:: 200006066

Select item 20000936217.

Round up hi-load herbicide treatment for 2 h

(Submitter supplied) The number and type of synthetic chemicals that are being produced worldwide continues to increase significantly. While these industrial chemicals provide numerous benefits, there is no doubt that some have potential to damage the environment and health. Toxicity must be evaluated and use must be carefully controlled and monitored in order to minimize potential damage. DNA microarray technology has become an important new technique in toxicology. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platforms:: GPL6004 GPL5994 GPL6003
3 Samples

Download data: GPR

Series

Accession:: GSE9362

ID:: 200009362

Select item 20000936418.

Sodium dodecyl sulfate treatment with 0.01% for 2 h

(Submitter supplied) The number and type of synthetic chemicals that are being produced worldwide continues to increase significantly. While these industrial chemicals provide numerous benefits, there is no doubt that some have potential to damage the environment and health. Toxicity must be evaluated and use must be carefully controlled and monitored in order to minimize potential damage. DNA microarray technology has become an important new technique in toxicology. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platforms:: GPL5996 GPL5997
3 Samples

Download data: GPR

Series

Accession:: GSE9364

ID:: 200009364

Select item 20001375719.

Comparison of the transcriptome of the ethanol adapted yeast and control at 10% ethanol

(Submitter supplied) In this study, using DNA microarray analysis, we compared the comprehensive expression profiles of two yeast trains, i.e, the previously obtained ethanol-adapted yeast strain and the parental strain as control (FY834), under the ethanol stress condition (YPD medium contained 10% ethanol). As a result, we identified certain genes and functional categories of the genes that are possible involved in growth under the ethanol stress condition.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL7698
2 Samples

Download data: GPR

Series

Accession:: GSE13757

ID:: 200013757

Select item 20000542120.

Divergence of Transcription Factor Binding Sites in Related Yeast Species

(Submitter supplied) A fundamental problem in biology is the molecular basis for divergence among related organisms. We have investigated the level of divergence of transcription factor binding sites for two key factors that regulate developmental processes in the budding yeasts. The genomic binding locations for the Ste12 and Tec1 transcription factors in S. cerevisiae, S. mikatae and S. bayanus were mapped by chromatin immunoprecipitation combined with microarrays (chIP chip)1, 2 and compared to one another. more...

Organism:: Saccharomyces bayanus; Candida albicans; Saccharomyces mikatae; Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by genome tiling array

4 related Platforms
27 Samples

Download data

Series

Accession:: GSE5421

ID:: 200005421

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