Similar studies for GEO DataSets (Select 200000442) - GEO DataSets

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Items: 20

Select item 2000004421.

(Submitter supplied) Investigatation into how genes with sex-differential expression profiles are distributed among the chromosomes in Drosophila. Assayed the expression of 14,142 predicted transcripts in competitive hybridizations and found a dramatic underrepresentation of X-chromosome genes showing high relative expression in male. This is the first report of sex-biased expression of the full (predicted) genome. Findings indicate that there is significant sex-biased expression, especially in gonads. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL20
46 Samples

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Series

Accession:: GSE442

ID:: 200000442

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Select item 2000782272.

The maleless gene mitigates global aneuploid effect and evolutionary shift from X to autosomes

(Submitter supplied) During sexual dimorphism, the loss of one entire X chromosome in Drosophila males is achieved largely via a broad genome-wide aneuploid effect. Exploring how MSL proteins and two large non coding RNAs (roX1 and roX2) modulate trans-acting aneuploid effect for equality to females, we employ a system biology approach (microarray) to investigate the global aneuploid effect of maleless(mle) mutation by disrupting MSL binding. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL72
6 Samples

Download data: CEL, TXT

Series

Accession:: GSE78227

ID:: 200078227

Select item 2000317233.

Sex-biased expression in Drosophila willistoni

(Submitter supplied) We performed mRNA sequencing of samples isolated from the heads, thoraxes, and abdomens of males and females of Drosophila willistoni to identify genes that are differentially expressed between the sexes.

Organism:: Drosophila willistoni

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL14359 GPL14358
8 Samples

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Series

Accession:: GSE31723

ID:: 200031723

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000317224.

Sex-biased gene expression in Drosophila melanogaster larvae

(Submitter supplied) Genes with sex-biased expression in adults experience unique evolutionary dynamics. It is unclear, however, whether the selection pressures responsible for these well documented patterns also act upon genes with sex-biased expression in other developmental stages. To examine this, we measured expression in male and female Drosophila melanogaster larvae.

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL6385
8 Samples

Download data: TXT

Series

Accession:: GSE31722

ID:: 200031722

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Select item 2000233095.

Sex-biased expression in heads of three Drosophila species

(Submitter supplied) Investigation of sex-biased expression across species have relied on measurements from whole flies which sample the extensive expression differences found in the germline and gonads of females and males. We wanted to examine genes with sex-biased expression in a somatic tissue to analyze patterns of genes with sex-biased expression in the context of a tissue more phenotypically similar between females and males. more...

Organism:: Drosophila mojavensis; Drosophila pseudoobscura; Drosophila melanogaster

Type:: Expression profiling by array

Platforms:: GPL4631 GPL4630 GPL4629
24 Samples

Download data: FTR, PAIR, TXT

Series

Accession:: GSE23309

ID:: 200023309

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Select item 2000021196.

Global analysis of X chromosome dosage compensation

(Submitter supplied) We have conducted a global analysis of somatic dosage compensation and also asked if germ cell dosage compensate by microarray analysis of gene expression in wild-type tissues. To obviate the confounding effects of scatter and especially the skewed genomic distributions of genes with sex-biased expression in both the soma and germline [there are fewer X chromosome genes with male-biased expression], we used mutations that transform sexual identity. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL20
27 Samples

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Series

Accession:: GSE2119

ID:: 200002119

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Select item 2001537807.

Two distinct mechanisms for X chromosome dosage compensation in Anopheles and Drosophila

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Anopheles gambiae; Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL25232 GPL23323
32 Samples

Download data: BW

Series

Accession:: GSE153780

ID:: 200153780

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Select item 2001537788.

Two distinct mechanisms for X chromosome dosage compensation in Anopheles and Drosophila [ChIP-seq]

(Submitter supplied) Heteromorphic sex chromosomes induce potentially deleterious gene expression imbalances that are frequently corrected by dosage compensation (DC). Three distinct molecular strategies to achieve DC have been previously described in nematodes, fruit flies and mammals. The reason for these mechanistic differences remain unclear: Are they a consequence of distinct genomes and gene content, functional or ecological constraints, or random initial commitment to an evolutionary trajectory? Here, we study DC in the malaria mosquito Anopheles gambiae. more...

Organism:: Anopheles gambiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25232
12 Samples

Download data: BW

Series

Accession:: GSE153778

ID:: 200153778

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Select item 2001537759.

Two distinct mechanisms for X chromosome dosage compensation in Anopheles and Drosophila [RNA-seq]

Organism:: Anopheles gambiae; Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL25232 GPL23323
20 Samples

Download data: TXT

Series

Accession:: GSE153775

ID:: 200153775

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Select item 20008344410.

Expansion of GA dinucleotide repeats increases the density of CLAMP binding sites on the X-chromosome to promote Drosophila dosage compensation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster; Drosophila miranda

Type:: Genome binding/occupancy profiling by high throughput sequencing; Genome binding/occupancy profiling by array

Platforms:: GPL17275 GPL22022 GPL22023
10 Samples

Download data: BROADPEAK, TXT

Series

Accession:: GSE83444

ID:: 200083444

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Select item 20008344211.

CLAMP Protein Binding Microarray (PBM) experiment

(Submitter supplied) To investigate the DNA binding specificity of the CLAMP protein, we have designed a custom PBM to interrogate the binding of CLAMP to DNA sequences extracted from the Drosophila melanogaster genome. Specific regions were extracted based on ChIP-seq data, motif occurence and proximity to gene transcription start sites.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by array

Platform:: GPL22023
2 Samples

Download data: TXT

Series

Accession:: GSE83442

ID:: 200083442

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Select item 20008343512.

Expansion of GA dinucleotide repeats increases the density of CLAMP binding sites on the X-chromosome to promote Drosophila dosage compensation [ChIP-Seq]

(Submitter supplied) ChIP-seq was performed to compare binding the genome-wide binding profile of the CLAMP transcription factor in two different Drosophila species.

Organism:: Drosophila miranda; Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL22022 GPL17275
8 Samples

Download data: BROADPEAK

Series

Accession:: GSE83435

ID:: 200083435

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Select item 20006057113.

RNA-Seq of female, male, and sex-transformed Drosophila melanogaster heads from flies heterozygous for deletions on chromosome X and 3L

(Submitter supplied) To measure the response to gene dose, we performed mRNA-Seq of fly heads with molecularly defined deletions constructed from DrosDel deficiency lines (Ryder et al. Genetics 2007, 177(1):615-29) on the Illumina HiSeq 2000 platform.

Organism:: Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13304
249 Samples

Download data: TXT

Series

Accession:: GSE60571

ID:: 200060571

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Select item 20004580114.

The genomic distribution of sex-biased genes in Drosophila serrata: X-chromosome demasculanisation, feminisation, and hyper-expression in both sexes

(Submitter supplied) Data from whole-body, head, thorax, abdomen, ovaries, testes and accessory glands was used to assess possible causes of a non-random distribution of sex-biased genes (sexually dimorphic expression). All samples were derived from virgin adult flies.

Organism:: Drosophila serrata

Type:: Expression profiling by array

Platform:: GPL16969
176 Samples

Download data: PAIR

Series

Accession:: GSE45801

ID:: 200045801

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Select item 20011577915.

RNA-seq data in WT, roX1, roX2, roX1roX2 mutants in D. melanogaster

(Submitter supplied) Study of single and double mutants of the two roX RNAs in D. melanogaster

Organism:: Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17275
13 Samples

Download data: TXT, XLSX

Series

Accession:: GSE115779

ID:: 200115779

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Select item 20001559316.

Sex-dependent and -independent X-chromosome histone modifications in Drosophila melanogaster

(Submitter supplied) Drosophila X chromosomes are subject to dosage compensation in males and are known to have a specialized chromatin structure in the male soma. We are interested in how specific chromatin structure change contributes to X chromosome hyperactivity and dosage compensation. We have conducted a global analysis of localize two dosage compensation complex dependent histone marks H4AcK16 and H3PS10 and one dosage compensation complex independent histone mark H3diMeK4 in the genome, especially on X chromosome by ChIP-chip approach in both male and female adult flies. more...

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by array; Other

Platforms:: GPL20 GPL9058
17 Samples

Download data: GPR, TXT

Series

Accession:: GSE15593

ID:: 200015593

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Select item 20003293117.

ENCODE Cold Spring Harbor Labs Long RNA-seq (hg18)

(Submitter supplied) This track depicts high throughput sequencing of long RNAs (>200 nt) from RNA samples from tissues or subcellular compartments from ENCODE cell lines. The overall goal of the ENCODE project is to identify and characterize all functional elements in the sequence of the human genome. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL9052
3 Samples

Download data: BB

Series

Accession:: GSE32931

ID:: 200032931

PubMed Full text in PMC Similar studies ENCODE SRA Run Selector

Select item 20003076118.

Mammalian X upregulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Mus musculus x Mus spretus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array; Expression profiling by array

9 related Platforms
60 Samples

Download data: BED, BIGWIG, CEL, GFF, PAIR, TXT

Series

Accession:: GSE30761

ID:: 200030761

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Select item 20003069019.

Expression analysis in mouse female PGK12.1 ES cells by RNA-seq

(Submitter supplied) Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance in the number of X-chromosomes between the sexes, but is also hypothesized to correct dosage imbalance within cells due to mono-allelic X expression and bi-allelic autosomal expression, by upregulating X-linked genes (termed âOhnoâs hypothesisâ). more...