U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.

Genome-wide transcriptional response of an Avian Pathogenic Escherichia coli (APEC) Pst Mutant

(Submitter supplied) Many reports show an association between the Pst system, the Pho regulon related genes and bacterial virulence. Our previous results showed that a functional Pst system is required for full virulence, resistance to serum, polymyxin B and acid shock. However, the interplay between the Pst system and virulence has an unknown molecular basis. To understand global APEC virulent strain responses to Pho regulon activation, we conducted transcriptome profiling experiments comparing the APEC chi7122 strain and its isogenic Pst mutant grown in rich phosphate medium using the Affymetrix GeneChip® E. more...
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL3154
8 Samples
Download data: CEL
Series
Accession:
GSE9178
ID:
200009178
2.

Genome-wide Analysis of the Pho Regulon in a pstCA mutant of Citrobacter rodentium

(Submitter supplied) to investigate global gene expression of C. rodentium strain ICC169 and its isogenic pstCA and phoB mutants when grown in phosphate-rich and phosphate-low medium
Organism:
Citrobacter rodentium
Type:
Expression profiling by array
Platform:
GPL7345
16 Samples
Download data: TXT
Series
Accession:
GSE40906
ID:
200040906
3.

Expression data from an Avian pathogenic Escherichia coli strain

(Submitter supplied) Avian pathogenic Escherichia coli strains frequently cause extra-intestinal infections and are responsible for significant economic losses in the poultry industry worldwide. APEC isolates are closely related to human extraintestinal pathogenic E.coli strains and may also act as pathogens for humans. In this work, three type VI secretion systems were deleted to analyze which pathogenicity characteristics would change in the mutants, compared to wild type strain (SEPT 362).
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL3154
4 Samples
Download data: CEL, TXT
Series
Accession:
GSE21893
ID:
200021893
4.

PhoB Activates Escherichia coli O157:H7 Virulence Factors in Response to Inorganic Phosphate Limitation

(Submitter supplied) In E. coli the phosphate homeostasis is regulated by the Pst system and the two-component system PhoB/R. Pathogens like E. coli O157:H7 are responsible for many outbreaks and can be found and survive in poor inorganic phosphate (Pi) environments. To understand global EHEC O157:H7 EDL933 strain responses to Pi-starvation, we compared the transcriptomes of EDL933 the WT strain grown in MOPS Pi rich medium and that grown in MOPS Pi poor medium, using the Affymetrix GeneChip® E. more...
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL3154
9 Samples
Download data: CEL
Series
Accession:
GSE50529
ID:
200050529
5.

comparison of virulence factors and expression of specific genes of UPEC and APEC in vivo and in vitro

(Submitter supplied) To gain further information of the correlation and pathogenisis of UPEC and APEC, the in vivo expression of 152 specific genes in both murine urinary tract infection (UTI) model and chicken challenge model were compared to that of UPEC U17 and APEC E058 grown statically to exponential phase in rich medium, respectively.
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL6870
4 Samples
Download data: LSR
Series
Accession:
GSE11509
ID:
200011509
6.

Transcriptome analysis of Escherichia coli K-12 and ada mutant

(Submitter supplied) Alkylation damage to DNA occurs when cells encounter alkylating agents in the environment or when active alkylators are generated by nitrosation of amino acids in metabolic pathways. To cope with DNA alkylation damage, cells have evolved genes that encode proteins with alkylation-specific DNA repair activities. It is notable that these repair systems are conserved from bacteria to humans. In Escherichia coli, cells exposed to a low concentration of an alkylating agent, such as N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate (MMS), show a remarkable increase in resistance to both the lethal and mutagenic effects of subsequent high-level challenge treatments with the same or other alkylating agents. more...
Organism:
Escherichia coli; Escherichia coli K-12
Type:
Expression profiling by array
Platform:
GPL5475
7 Samples
Download data: GPR
Series
Accession:
GSE16565
ID:
200016565
7.

Amino acid/Nucleotide perturbation in Escherichia coli

(Submitter supplied) Wild-type E. coli are prototrophic for all amino acid and nucleotides. These are synthesized by a network of interconnected metabolic pathways from a handful precursors molecules, which are regulated at the level of gene expression. It was hypothesized in this study, that since metabolic pathways are interconnected, transcriptional regulation should be shared across multiple pathways. To uncover these regulatory interactions, cells growing at steady state were perturbed by the addition of an end-metabolite (aa or nt), and were allowed to recover. more...
Organism:
Escherichia coli; Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by array
Platform:
GPL3503
22 Samples
Download data: GPR
Series
Accession:
GSE15409
ID:
200015409
8.

E coli MG1655 biofilm and planktonic gene expression

(Submitter supplied) Bacteria growing as surface-adherent biofilms are better able to withstand chemical and physical stresses than their unattached, planktonic counterparts. Using transcriptional profiling and quantitative PCR, we observed a previously uncharacterized gene, yjfO, to be upregulated during Escherichia coli MG1655 biofilm growth in a chemostat on serine-limited defined medium. A yjfO mutant, developed through targeted insertion mutagenesis, and a yjfO-complemented strain, were obtained for further characterization. more...
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL189
4 Samples
Download data
Series
Accession:
GSE18362
ID:
200018362
9.

Identification of the Escherichia coli HU regulon

(Submitter supplied) The physiological role of the various nucleoid-associated proteins in bacteria and HU in particular has been addressed in a number of studies but remains so far not fully understood. In this work, a genome-wide microarray hybridization approach, combined with in vivo genetic experimentation, has been performed in order to compare and evaluate the effect of HUalpha, HUbeta and HUalphabeta on the transcription of the Escherichia coli K12 genes as a function of growth phase. more...
Organism:
Escherichia coli; Escherichia coli K-12
Type:
Expression profiling by array
Platform:
GPL199
26 Samples
Download data: CEL, EXP
Series
Accession:
GSE11183
ID:
200011183
10.

Expression profiles during cell death programmed by a restriction-modification system in E. coli

(Submitter supplied) Genetically programmed deaths play important roles in the biology of unicellular prokaryotic cells. Some gene complexes force their maintenance on the host bacterial cells by killing cells that have lost them. This form of programmed death called post-segregational killing or genetic addiction is brought about by several Type II restriction-modification gene complexes, through restriction attack on the undermethylated chromosome, and underlie their behavior as selfish mobile elements. more...
Organism:
Escherichia coli; Escherichia coli K-12
Type:
Expression profiling by array
Platform:
GPL199
24 Samples
Download data: CEL
Series
Accession:
GSE7326
ID:
200007326
11.

Stress response in the yajL (DJ-1 homolog) mutant of Escherichia coli

(Submitter supplied) YajL is the most closely related Escherichia coli homolog of Parkinsonism-associated protein DJ-1, a protein with a yet undefined function in the oxidative stress response. YajL protects cells against oxidative stress-induced protein aggregation and functions as a covalent chaperone for the thiol proteome, including FeS proteins. To clarify the cellular responses to YajL deficiency, transcriptional profiling of the yajL mutant was performed. more...
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL3154
4 Samples
Download data
Series
Accession:
GSE42702
ID:
200042702
12.

The YbjN regulon in Escherichia coli

(Submitter supplied) YbjN, an enterobacteria-specific protein, is a multicopy suppressor of ts9 temperature sensitivity in Escherichia coli. Microarray study revealed that the expression level of ybjN was inversely correlated with the expression of flagellar, fimbrial and acid resistance genes. Over-expression of ybjN significantly down-regulated genes involved in the citric acid cycle, glycolysis, the glyoxylate shunt, oxidative phosphorylation, and amino acid and nucleotide metabolism. more...
Organism:
Escherichia coli str. K-12 substr. MG1655; Escherichia coli; Escherichia coli O157:H7 str. EDL933; Escherichia coli CFT073; Escherichia coli O157:H7 str. Sakai
Type:
Expression profiling by array
Platform:
GPL13359
8 Samples
Download data: TXT
Series
Accession:
GSE28630
ID:
200028630
13.

Role of Manganese Efflux for Signaling and Pathogenesis in Streptococcus pneumonia

(Submitter supplied) Microarray analysis of Streptococcus pneumoniae TIGR4 transcriptome in response to manganese as the transcriptome changes in response to intracellular manganese accumulation via a mutation in sp1552/mntE a manganese efflux protein.
Organism:
Streptococcus pneumoniae TIGR4
Type:
Expression profiling by array
Platform:
GPL8038
6 Samples
Download data: GPR, PDF
Series
Accession:
GSE14324
ID:
200014324
14.

Analysis of growth-phase regulated genes in Streptococcus agalactiae by global transcript profiling

(Submitter supplied) We determined dynamic behavior of S. agalactiae transcriptome during growth in THY medium and detected growth phase regulated genes
Organism:
Streptococcus agalactiae
Type:
Expression profiling by array
Platform:
GPL6923
12 Samples
Download data: CEL
Series
Accession:
GSE12238
ID:
200012238
15.

Global Transcriptional Response of Escherichia coli Exposed In Situ to Different Low-Dose Ionizing Radiation Sources

(Submitter supplied) Characterization of biological and chemical responses to ionizing radiation by various organisms is essential for potential applications in bioremediation, alternative modes of detecting nuclear material, and national security. Escherichia coli DH10β is an optimal system to study the microbial response to low-dose ionizing radiation at the transcriptional level because it is a well-characterized model bacterium and its responses to other environmental stressors, including those to higher radiation doses, have been elucidated in prior studies. more...
Organism:
Escherichia coli
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28126
30 Samples
Download data: TXT
Series
Accession:
GSE208658
ID:
200208658
16.

Prediction of Cross-resistance and Collateral Sensitivity by Gene Expression profiles and Genomic Mutations.

(Submitter supplied) In adaptive evolution, an increase in fitness to an environment is frequently accompanied by changes in fitness to other environmental conditions, called cross-resistance and sensitivity. Although the networks between fitness changes affect the course of evolution substantially, the mechanisms underlying such fitness changes are yet to be fully elucidated. Herein, we performed high-throughput laboratory evolution of Escherichia coli under various stress conditions using an automated culture system, and quantified how the acquisition of resistance to one stressor alters the resistance to other stressors. more...
Organism:
Escherichia coli; Escherichia coli str. K-12 substr. MDS42
Type:
Expression profiling by array
Platform:
GPL18948
124 Samples
Download data: TXT
Series
Accession:
GSE89746
ID:
200089746
17.

Gene expression analysis of E. coli strains provides insights into the role of gene regulation in diversification

(Submitter supplied) Escherichia coli spans a genetic continuum from enteric strains to several phylogenetically distinct, atypical lineages that are rare in humans, but more common in extra-intestinal environments. To investigate the link between gene regulation, phylogeny and diversification in this species, we analyzed global gene expression profiles of four strains representing distinct evolutionary lineages, including a well-studied laboratory strain, a typical commensal (enteric) strain and two environmental strains. more...
Organism:
Escherichia coli
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14548
24 Samples
Download data: TXT
Series
Accession:
GSE77325
ID:
200077325
18.

Evolution of gene expression during an adaptive diversification event

(Submitter supplied) During a 1,000 generations evolution experiment, two types of bacteria (S and L) repeatedly diverged from a common ancestor (A) in a fully sympatric seasonal environment containing glucose and acetate. We compare the transcription profile of the two derived types and the common ancestor in order to investigate the metabolic modifications associated with this adaptive diversification event. Keywords: time point, experimental evolution
Organism:
Escherichia coli
Type:
Expression profiling by array
Platform:
GPL5767
40 Samples
Download data
Series
Accession:
GSE8965
ID:
200008965
19.

Evolved polymorphism in E. coli

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Escherichia coli K-12; Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by array; Genome variation profiling by array
Platform:
GPL8872
45 Samples
Download data: GPR
Series
Accession:
GSE17314
ID:
200017314
20.

Array comparative genome hybridization of an evolved polymorphism in E. coli

(Submitter supplied) Microbial populations founded by a single clone and propagated under resource limitation can become polymorphic. We sought to understand how stable polymorphism arose in an Escherichia coli population that evolved for 765 generations under continuous glucose limitation. Apart from a 29 kb deletion in the dominant clone, no large-scale genomic changes distinguish evolved clones from their common ancestor. more...
Organism:
Escherichia coli K-12; Escherichia coli str. K-12 substr. MG1655
Type:
Genome variation profiling by array
Platform:
GPL8872
4 Samples
Download data: GPR
Series
Accession:
GSE17277
ID:
200017277
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=7|qty=11|blobid=MCID_670b3b4c475a635e85d5ee78|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center