Similar studies for GEO DataSets (Select 200041213) - GEO DataSets

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Items: 20

Select item 2000412131.

Identification of a set of miRNAs differentially expressed in transiently TIA-depleted HeLa cells by genome-wide profiling

(Submitter supplied) Background: T-cell intracellular antigen (TIA) proteins function as regulators of cell homeostasis. These proteins control gene expression globally at multiple levels in response to dynamic regulatory changes and environmental stresses. Herein we identified a micro(mi)RNA signature associated to transiently TIA-depleted HeLa cells and analyzed the potential role of miRNAs combining genome-wide analysis data on mRNA and miRNA profiles. more...

Organism:: Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae; Homo sapiens; Murid betaherpesvirus 1; Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Human immunodeficiency virus 1; Human gammaherpesvirus 8

Type:: Non-coding RNA profiling by array

Platform:: GPL13273
3 Samples

Download data: TXT

Series

Accession:: GSE41213

ID:: 200041213

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Select item 2000519792.

Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles

(Submitter supplied) Purpose: The goal of this study is to explore the role of miRNAs in dairy cow response to E. coli and S. aureus, mastitis causing pathogens, is not well understood. Results: The global expression of miRNAs in bovine mammary epithelial cells (MAC-T cells) challenged with heat-inactivated Staphylococcus aureus (S. aureus) or Escherichia coli (E. coli) bacteria (treatments: 6, 12, 24 and 48 hr) and without challenge (control: 0, 6, 12, 24 and 48 hr) was profiled using next-generation-sequencing. more...

Organism:: Bos taurus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL17875
13 Samples

Download data: TXT

Series

Accession:: GSE51979

ID:: 200051979

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Select item 2001730803.

Screening and identification of differentially expressed microRNAs in diffuse large B-cell lymphoma based on microRNA microarray

(Submitter supplied) to screen and identify differentially expressed microRNAs (miRNAs) between diffuse large B-cell lymphoma (DLBCL) and control (lymph node reactive hyperplasia, LRH) groups, investigate whether miRNAs associated with DLBCL and could serve as potential therapeutic targets.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL25134
10 Samples

Download data: TXT

Series

Accession:: GSE173080

ID:: 200173080

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Select item 2000329064.

Differential expressed miRNAs in Multi-stages and Lymphoid node metastasis of Nasopharyngeal Carcinoma

(Submitter supplied) According to the evolution of the NPC, with normal time series, we identified microRNAs (miRNAs) showing robust differential expression between nasopharyngeal carcinomas (NPCs) and normal healthy nasopharyngeal epithelial samples. This research use miRNA chip testing at different stages in 12 cases of NPC (TNM Ⅰ - II, III, IV each stage 4 cases), 4 patients matched sample and transfer lymphoma 6 samples. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL11350
22 Samples

Download data: TXT

Series

Accession:: GSE32906

ID:: 200032906

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Select item 2001515615.

MicroRNA Sequencing of CD34+ Sorted Adipose Stem Cells (ASCs) Undergoing Endotheliogenesis

(Submitter supplied) In this study, CD34+ ASCs sorted using magnetic bead separation were induced to differentiate along the endothelial pathway. miRNA sequencing of ASCs at day 3, 9 and 14 of endothelial differentiation was performed on Ion Proton sequencing system. The data obtained by this high-throughput method was aligned to the human genome HG38 and the differentially expressed miRNAs during endothelial differentiation at various timepoints (day 3, 9 and 14) were identified.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL17303
12 Samples

Download data: CSV, TXT

Series

Accession:: GSE151561

ID:: 200151561

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Select item 2001107846.

miRNA expression profiles of HeLa-Cas9 and NCI-N87 cells

(Submitter supplied) MicroRNAs (miRNAs) play an important role in the regulation of gene expression and are often dysregulated in disease. The recent development of the CRISPR-Cas9 gene-editing system, composed of the Cas9 nuclease in complex with a single guide RNA (sgRNA), allows researchers to direct DNA cleavage at a predetermined site and to conduct genome-scale knockout screens. To determine the functional role of miRNAs in cancer, we designed and constructed a library of 7,382 sgRNAs to target 85% of the 1,881 annotated human miRNA stem-loops. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16791
5 Samples

Download data: CSV

Series

Accession:: GSE110784

ID:: 200110784

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Select item 2002353737.

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice

(Submitter supplied) Individual miRNA analyzed were successfully constructed through nanostring technology of a total of 577 mouse miRNAs in 20 number of SHAM mice and 20 number of T. denticola infected mice, which have been euthanized on the end of 16 weeks infection study.

Organism:: Treponema denticola; Mus musculus

Type:: Expression profiling by array

Platform:: GPL33511
40 Samples

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Series

Accession:: GSE235373

ID:: 200235373

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Select item 2002353728.

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_Td_data]

Organism:: Treponema denticola; Mus musculus

Type:: Expression profiling by array

Platform:: GPL33511
10 Samples

Download data: CSV

Series

Accession:: GSE235372

ID:: 200235372

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Select item 2002353719.

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_sham_data]

Organism:: Treponema denticola; Mus musculus

Type:: Expression profiling by array

Platform:: GPL33511
10 Samples

Download data: CSV

Series

Accession:: GSE235371

ID:: 200235371

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Select item 20023537010.

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_Td_data]

Organism:: Treponema denticola; Mus musculus

Type:: Expression profiling by array

Platform:: GPL33511
10 Samples

Download data: CSV

Series

Accession:: GSE235370

ID:: 200235370

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Select item 20023536911.

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_sham_data]

Organism:: Treponema denticola; Mus musculus

Type:: Expression profiling by array

Platform:: GPL33511
10 Samples

Download data: CSV

Series

Accession:: GSE235369

ID:: 200235369

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Select item 20016935412.

Integrative analysis of miRNA-mRNA expression profiles in esophageal fibrosis after ESD

(Submitter supplied) The present results provided an improved understanding of the changes in the microenvironment during the process of esophageal fibrosis, as well as novel potential targets for the treatment of esophageal fibrosis and BES.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL25134
10 Samples

Download data: TXT

Series

Accession:: GSE169354

ID:: 200169354

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Select item 20005974813.

MicroRNA expression in chicken cecum following Salmonella Enteritidis infection

(Submitter supplied) White leghorn layers were infected with Salmonella Enteritidis. The cecum were collected at 7 days post infection for total RNA isolation. The significantly expressed microRNAs between infected and non-infected chickens were identified through Solexa sequencing technology.

Organism:: Gallus gallus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16133
6 Samples

Download data: TXT

Series

Accession:: GSE59748

ID:: 200059748

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Select item 20008618614.

miRNA expression data before and after TGF-β treatment and Ago2-associated transcripts in lung fibroblasts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Other; Non-coding RNA profiling by array

Platforms:: GPL21185 GPL8786
34 Samples

Download data: CEL

Series

Accession:: GSE86186

ID:: 200086186

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Select item 20008618515.

miRNA expression data in unstimulated and TGF-β1-stimulated lung fibroblasts

(Submitter supplied) Lung fibroblasts play an important role in extracellular matrix homeostasis and this process is mainly regulated by transforming growth factor-beta (TGF-β). Hence, lung fibroblasts are postulated to play a crucial role in aberrant lung tissue repair and remodeling, which is a main factor in lung diseases like COPD. In this study, the effect of TGF-β1 on the miRNA expression in parenchymal lung fibroblasts is investigated.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL8786
18 Samples

Download data: CEL

Series

Accession:: GSE86185

ID:: 200086185

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Select item 20008618316.

mRNA expression profiling after Ago2-immunoprecipitation (IP) in unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts of two control subjects

(Submitter supplied) To identify the target gene repertoire of miRNAs (i.e. the miRNA-targetome) of unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts, Ago2-IP was performed followed by mRNA expression profiling.

Organism:: Homo sapiens

Type:: Other

Platform:: GPL21185
16 Samples

Download data: TXT

Series

Accession:: GSE86183

ID:: 200086183

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Select item 20013170317.

MiRNA-seq in blood of myasthenia gravis (MG) patients responder and non-responder to immunosuppressive treatment

(Submitter supplied) Purpose: to identify specific miRNAs as biomarkers associated with immunosuppressive treatment response in MG patients. Methods: Blood miRNome profiles of 15 responder and 15 non-responder MG patients by miRNA-seq using Illumina NextSeq 500 sequencing. Raw data were de-multiplexed and FASTQ files for each sample were generated using the bcl2fastq software. FASTQ data were checked using the FastQC tool. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL18573
30 Samples

Download data: XLSX

Series

Accession:: GSE131703

ID:: 200131703

PubMed Similar studies SRA Run Selector

Select item 20006826718.

Identification of conserved and species-specific microRNAs in tea plant (Camellia sinensis) by deep sequencing

(Submitter supplied) In this study, it is noticeable that 32 tea-specific miRNAs were confirmed on the base of genome survey, using deep sequencing and microarray hybridization, and many miRNAs might associate with secondary metabolites synthesis.

Organism:: Camellia sinensis

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL20107
1 Sample

Download data: TXT

Series

Accession:: GSE68267

ID:: 200068267

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Select item 20005940119.

Gene expression profiles of rat enamel organs (secretory--stage and maturation stage)

(Submitter supplied) We conducted the genome-wide mRNA expression profiling in parallel with miRNA expression profiling using RNA samples extracted from rat incisor enamel organs, so as to refine the number of predicted gene targets for miRNA regulators.

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6101
8 Samples

Download data: TXT

Series

Accession:: GSE59401

ID:: 200059401

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Select item 20005463020.

Identification of latent tuberculosis infection-related microRNAs in human U937 macrophages expressing Mycobacterium tuberculosis Hsp16.3

(Submitter supplied) Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an important role in Mtb persistence within macrophages. However, the mechanism of LTBI remains elusive. The aim of this study was to delineate LTBI-related miRNA expression in U937 macrophages expressing Mtb Hsp16.3 protein. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18244
2 Samples

Download data: TXT

Series

Accession:: GSE54630

ID:: 200054630

PubMed Full text in PMC Similar studies Analyze with GEO2R

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