GEO DataSets

(Submitter supplied) The aim of the study is to identify the global messenger RNA (mRNA) and long noncoding RNA (lncRNA) expression profiling in peripheral blood from thirty patients with Obsessive Compulsive Disorders (OCD) and thirty paired normal controls.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL19612

60 Samples

Download data: TXT

(Submitter supplied) RNA-seq technology was used to detect the differentially expressed LncRNAs and mRNAs between five paired pSS patients and healthy control PBMCs. In this study, 44 out of 1772 LncRNAs and 1034 out of 15424 mRNAs were expressed differentially in the PBMCs of pSS patients.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL16791

10 Samples

Download data: TXT

(Submitter supplied) We performed a genome-wide analysis of lncRNA expression to identify novel targets for the further study of liver metastasis in CRC. Samples obtained from CRC patients were analyzed using Arraystar human 8×60K lncRNA/mRNA v3.0 microarrays chips to find differentially expressed lncRNAs and mRNAs; The results were confirmed by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). The differentially expressed lncRNAs and mRNAs were identified through fold-change filtering. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL16956

12 Samples

Download data: TXT

(Submitter supplied) Transcripional profiling of lymphocytes from patients with amyotrophic lateral sclerosis (ALS) (n=11) and healthy control subjects (n=11). The goal was to determine disease response expression signatures relevant of ALS pathogenesis that affect brain and spinal cord. The reference design was used: each Cy5-labeled cRNA sample from ALS patient or healthy control subject was cohybridized on Agilent-014850 Whole Human Genome Microarray 4x44K G4112F with the reference pool formed with equal amounts of Cy3-labeled cRNAs from each sample from the healthy control group.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

22 Samples

Download data: TXT

(Submitter supplied) Objective: We explored the patterns of long non-coding RNA (lncRNA) expression in peripheral blood mononuclear cells (PBMCs) from patients with non-segmental vitiligo. Methods: We used high-throughput RNA sequencing technology to generate sequence data from five patients with non-segmental vitiligo alongside five normal healthy individuals, and then performed bioinformatics analyses to detect the differential expression of lncRNA in PBMCs. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL24676

10 Samples

Download data: TXT

(Submitter supplied) To determine the expression profile and clinical significance of long non-coding RNAs (lncRNAs) in peripheral blood mononuclear cells (PBMCs) of patients with primary gout and healthy control subjects. Human lncRNA microarrays were used to identify the differentially expressed lncRNAs and mRNAs in primary gout (n=6) and healthy subjects (n=6). Bioinformatics analyses were performed to predict the roles of differently expressed lncRNAs and mRNAs. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL21827

12 Samples

Download data: TXT

(Submitter supplied) This study aimed to identify the crucial molecules and explore the function of noncoding RNAs and related pathways in IDD. We randomly selected 3 samples each from an IDD and a spinal cord injury group (control) for RNA-sequencing. We identified 463 differentially-expressed long noncoding RNAs (lncRNAs), 47 differentially-expressed microRNAs (miRNAs), and 1,334 differentially-expressed mRNAs in IDD. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL24676

12 Samples

Download data: CSV, TXT

(Submitter supplied) We conducted the genome-wide mRNA expression profiling in parallel with miRNA expression profiling using RNA samples extracted from rat incisor enamel organs, so as to refine the number of predicted gene targets for miRNA regulators.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL6101

8 Samples

Download data: TXT

(Submitter supplied) Up to date the studies examining the gene expression profiles in response to exposure to nickel compounds have only been conducted using in vitro tissue culture systems. Here, we have compared the gene expression profiles in peripheral blood mononuclear cells (PMCs) of eight nickel refinery workers in Jinchang, China to the expression profiles of referent subjects with only environmental exposure.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4974

Platform:

GPL6244

18 Samples

Download data: CEL

Analysis of peripheral blood mononuclear cells from 8 nickel refinery workers. Occupational exposure to nickel is associated with an increased risk of lung and nasal cancers. Results provide insight into molecular mechanisms underlying nickel carcinogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 stress sets

Platform:

GPL6244

Series:

GSE40392

18 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Human alphaherpesvirus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Human betaherpesvirus 5; Rhadinovirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Cytomegalovirus; Betapolyomavirus macacae; Mus musculus; Rattus norvegicus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL15314 GPL16016

60 Samples

Download data: TXT

(Submitter supplied) The study profiles genome-wide mRNA expression in blood from 18 early-onset SZ (EOS) cases and 12 healthy controls. A total of 1070 mRNAs were detected by the microarrays in our samples.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL15314

30 Samples

Download data: TXT

(Submitter supplied) Large-scale gene expression profiling of peripheral blood mononuclear cells from Rheumatoid Arthritis (RA) patients could provide a molecular description that reflects the contribution of diverse cellular responses associated with this disease. The aim of our study is to identify peripheral blood gene expression profiles for RA patients, using Illumina technology, to gain insights into RA molecular mechanisms. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3794

Platform:

GPL6102

33 Samples

Download data: TXT

Analysis of peripheral blood mononuclear cells of rheumatoid arthritis (RA) patients. Results provide insight into the molecular pathogenesis and pathophysiology of RA.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL6102

Series:

GSE15573

33 Samples

Download data

(Submitter supplied) Long noncoding RNAs (lncRNAs) are pervasively transcribed and have a direct role in the regulation of genes involved in neural plasticity and cognitive function. Moreover, alterations in the expression of several lncRNAs have been observed in some psychiatric disorders. However, changes in the expression of regulatory lncRNAs in MDD have not yet been reported. Using microarrays, we profiled the expression of 51513 lncRNAs and 35123 mRNAs in peripheral blood sampled from MDD patients as well as demographically-matched controls.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL17976

22 Samples

Download data: CEL, CHP

(Submitter supplied) Anorexia nervosa (AN), bulimia nervosa (BN), and obsessive-compulsive disorder (OCD) are complex psychiatric disorders with shared obsessive features, thought to arise from the interaction of multiple genes of small effect with environmental factors. Potential candidate genes for AN, BN, and OCD have been identified through clinical association and neuroimaging studies; however, recent genome-wide association studies of eating disorders (ED) so far have failed to report significant findings. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6947

133 Samples

Download data: TXT

(Submitter supplied) Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be involved in the pathogenesis of coronary artery disease (CAD). However, it remains to be extensively explored.Using microarray, we performed the transcriptome-wide lncRNA and mRNAs expression profile in peripheral blood mononuclear cells (PBMCs) of 93 CAD patients and 48 healthy controls. Gene Ontology (GO) and pathway analysis for differentially expressed mRNAs was used to investigate underlying biological associations of differentially expressed lncRNAs and create path-net to depict interactions of significant pathways. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL20115

141 Samples

Download data: JPG, TXT

(Submitter supplied) Type 2 diabetes mellitus is mainly affected by genetic and environmental factors, and long noncoding RNAs (lncRNAs) have been shown to be correlated with diabetes.LncRNA is expected to be a target for the treatment and prediction of type 2 diabetes. We used microarrays to detail the lncRNAs and mRNAs expression in type 2 diabetes patients and healthy controls and obtained differentially expressed genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL22517

4 Samples

Download data: CEL, CHP

(Submitter supplied) Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separately, of CD4+ T lymphocytes isolated from CAMR patients compared to kidney transplant recipients with normal graft function and histology. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6480

10 Samples

Download data: TXT

(Submitter supplied) Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separately, of CD4+ T lymphocytes isolated from CAMR patients compared to kidney transplant recipients with normal graft function and histology. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL16770

9 Samples

Download data: TXT