Similar studies for GEO DataSets (Select 200078820) - GEO DataSets

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Items: 20

Select item 2000788201.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [H3K9me2]

(Submitter supplied) ChIP-chip analyses of lysine 9 dimethylated histone H3 in Shelterin mutants. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
6 Samples

Download data: TXT

Series

Accession:: GSE78820

ID:: 200078820

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000788232.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
22 Samples

Download data: TXT

Series

Accession:: GSE78823

ID:: 200078823

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000788223.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [Taz1]

(Submitter supplied) Occupancy profiling of Shelterin components in fission yeast. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
4 Samples

Download data: TXT

Series

Accession:: GSE78822

ID:: 200078822

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Select item 2000788214.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [Rec12]

(Submitter supplied) Occupancy profiling of Rec12 during fission yeast meiosis. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
1 Sample

Download data: TXT

Series

Accession:: GSE78821

ID:: 200078821

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Select item 2000788195.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [BrdU]

(Submitter supplied) BrdU profiling of replication activity in hydroxyurea treated synchronous culture of fission yeast. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
11 Samples

Download data: TXT

Series

Accession:: GSE78819

ID:: 200078819

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Select item 2000334046.

RNA elimination machinery targeting meiotic mRNAs promotes facultative heterochromatin formation

(Submitter supplied) Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
5 Samples

Download data: TXT

Series

Accession:: GSE33404

ID:: 200033404

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Select item 2000747417.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL16192 GPL6503
12 Samples

Download data: SGR, TXT

Series

Accession:: GSE74741

ID:: 200074741

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Select item 2000747408.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [ChIP-chip]

(Submitter supplied) Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast. Occupancy profiling of Red1, Mtl1, and Mmi1 proteins in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
10 Samples

Download data: TXT

Series

Accession:: GSE74740

ID:: 200074740

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Select item 2000747399.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [sRNA-seq]

(Submitter supplied) Co-transcriptional RNA processing and surveillance factors mediate heterochromatin formation in fission yeast. In addition to RNAi, RNA elimination machinery including MTREC (Mtl1-Red1 core) and the exosome are involved in facultative heterochromatin assembly, however, the exact mechanisms remain unclear. Here we show that RNA elimination factors cooperate with the conserved exoribonuclease Dhp1/Rat1/Xrn2, which couples pre-mRNA 3’-end processing to transcription termination, to promote premature termination and facultative heterochromatin formation at meiotic genes. more...

Organism:: Schizosaccharomyces pombe

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16192
2 Samples

Download data: SGR

Series

Accession:: GSE74739

ID:: 200074739

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20012314410.

CPF is required for heterochromatin assembly and gene silencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL16192
23 Samples

Download data: BEDGRAPH, BW, TXT

Series

Accession:: GSE123144

ID:: 200123144

PubMed Full text in PMC Similar studies

Select item 20012313811.

CPF is required for heterochromatin assembly and gene silencing [RNA-seq]

(Submitter supplied) RNA sequencing in Schizosaccharomyces pombe

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20584
4 Samples

Download data: TXT

Series

Accession:: GSE123138

ID:: 200123138

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20012313712.

CPF is required for heterochromatin assembly and gene silencing [ChIP-seq]

(Submitter supplied) Mapping of H3K9me2, 3' RNA processing and termination factors, and terminating RNA polymerase II in Schizosaccharomyces pombe

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL16192
19 Samples

Download data: BEDGRAPH, BW

Series

Accession:: GSE123137

ID:: 200123137

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20009327313.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [HU + BrdU IP]

(Submitter supplied) BrdU profiling of replication activity in synchronous culture of fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome variation profiling by genome tiling array

Platform:: GPL6503
2 Samples

Download data: TXT

Series

Accession:: GSE93273

ID:: 200093273

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Select item 20008890414.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL8908 GPL6503
20 Samples

Download data: TXT

Series

Accession:: GSE88904

ID:: 200088904

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890315.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [BrdU IP]

(Submitter supplied) BrdU profiling of replication activity in hydroxyurea treated synchronous culture of fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
4 Samples

Download data: TXT

Series

Accession:: GSE88903

ID:: 200088903

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890216.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [H3K9me2 ChIP]

(Submitter supplied) H3K9me2 profiles and Fft3 occupancy in fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
7 Samples

Download data: TXT

Series

Accession:: GSE88902

ID:: 200088902

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890117.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [H3-FLAG ChIP]

(Submitter supplied) H3-FLAG incorporation in Schizosaccharomyces pombe Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL8908
7 Samples

Download data: TXT

Series

Accession:: GSE88901

ID:: 200088901

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007611418.

Expression profiling and ChIP-chip of Schizosaccharomyces pombe strains wildtype, erh1∆, and ccr4∆

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL16192 GPL6503
21 Samples

Download data: FPKM_TRACKING, TXT

Series

Accession:: GSE76114

ID:: 200076114

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007611219.

Expression profiling of fission yeast strains: wild-type, erh1∆, and ccr4∆

(Submitter supplied) We report gene expression profiling in the fission yeast Schizosaccharomyces pombe. We performed high-throughput sequencing of RNA isolated from wild-type, erh1∆, and ccr4∆ strains. We find that many meiotic gene containing degradation sequence DSR are expressed in vegetative erh1∆, while these meiotic mRNAs do not increase in ccr4∆, indicating that Erh1 and Ccr4 target different set of genes during vegetative growth.