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Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Affymetrix]
PubMed Full text in PMC Similar studies
Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome
Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Illumina]
PubMed Full text in PMC Similar studies Analyze with GEO2R
Synergistic targeting of estrogen-receptor positive breast cancers by MDM2 inhibition in combination with endocrine therapy or CDK4/6 inhibition
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
High CDK6 protects cells from fulvestrant-mediated apoptosis and is a predictor of resistance to fulvestrant in estrogen receptor-positive metastatic breast cancer
Expression data from LncRNA TROJAN knockdown breast cancer cells
Gene expression analyses of palbociclib treated ER+ breast cancer cell lines as assessed by RNA-seq
Loss of the FAT1 tumor suppressor promotes resistance to CDK4/6 inhibitors via the Hippo pathway
Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to ER-directed therapies
PubMed Similar studies Analyze with GEO2RSRA Run Selector
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq]
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq]
CDK4/6 inhibitors in ER positive breast cancers
CDK4/6 inhibitor resistance in prostate cancer
SMAD2 binding regions in breast cancer cell line and RNA-seq transcriptome analyses in T47D
RNA-seq transcriptome analyses in T47D cells treated with ActA and Palbociclib.
SMAD2 binding regions in triple negative breast cancer cell line, Hs578T
PubMed Full text in PMC Similar studies SRA Run Selector
SMAD2 binding regions in estrogen receptor-positive breast cancer cell line, T47D
Breast Cell Lines: Experimental vs. Mixed Reference
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer
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