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Links from GEO DataSets

Items: 20

1.

Homo sapiens whole blood infected with Candida spp. (here: Candida glabrata)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida glabrata. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida glabrata gene expression.
Organism:
Nakaseomyces glabratus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24975
18 Samples
Download data: CSV
Series
Accession:
GSE114175
ID:
200114175
2.

Homo sapiens whole blood infected with Candida spp.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida albicans; Candida parapsilosis; Candida tropicalis; Nakaseomyces glabratus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
5 related Platforms
75 Samples
Download data
Series
Accession:
GSE114180
ID:
200114180
3.

Homo sapiens whole blood.

(Submitter supplied) RNA extracted at 240min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
3 Samples
Download data: CSV
4.

Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida tropicalis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida tropicalis gene expression.
Organism:
Homo sapiens; Candida tropicalis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24977
18 Samples
Download data: CSV
Series
Accession:
GSE114178
ID:
200114178
5.

Homo sapiens whole blood infected with Candida spp. (here: Candida parapsilosis)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida parapsilosis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Homo sapiens gene expression.
Organism:
Candida parapsilosis; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24976
18 Samples
Download data: CSV
Series
Accession:
GSE114177
ID:
200114177
6.

Homo sapiens whole blood infected with Candida spp. (here: Candida albicans)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida albicans SC5314. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.
Organism:
Homo sapiens; Candida albicans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24974
18 Samples
Download data: CSV
Series
Accession:
GSE114174
ID:
200114174
7.

Transcriptional responses of primary murine macrophages to four Candida species

(Submitter supplied) Candidiasis is an infection caused by yeasts of the genus Candida that ranges in severity from debilitating mucosal infections to disseminated disease with high mortality rates. C. albicans is the most common cause of infection, but non-albicans species collectively represent a significant disease burden. Disseminated disease rarely affects immunocompetent individuals, largely due to the action of innate immune cells, including macrophages, in controlling infection. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
21 Samples
Download data: TXT
Series
Accession:
GSE152700
ID:
200152700
8.

Comparative transcriptomic analysis of the response of CUG-clade Candida species to phagocytosis

(Submitter supplied) Pathogenic Candida fungi are a leading cause of opportunistic, hospital-associated bloodstream infections with high mortality rates, typically in immunocompromised patients. Several species, including C. albicans, the most prevalent cause of infection, belong to the monophyletic CUG clade of yeasts. Much is known about the interaction of C. albicans with innate immune cells, which are crucial for controlling infection. more...
Organism:
Mus musculus; Candida dubliniensis; Candida albicans; Lodderomyces elongisporus; Candida parapsilosis; Clavispora lusitaniae; Candida tropicalis
Type:
Expression profiling by high throughput sequencing
12 related Platforms
24 Samples
Download data: TXT
Series
Accession:
GSE151288
ID:
200151288
9.

Filamentation is Associated with Reduced Pathogenicity of Multiple Non-albicans Candida Species

(Submitter supplied) Candidiasis affects a wide variety of immunocompromised individuals, including HIV/AIDS patients and cancer patients on chemotherapy. Candida albicans, a major human fungal pathogen, accounts for about 50% of all cases, while the remainder are caused by the less pathogenic non-albicans Candida species (NACS). These species are believed to be less pathogenic, in part, because they do not filament as readily or robustly as C. more...
Organism:
Candida tropicalis; Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21876 GPL18663
16 Samples
Download data: TXT
Series
Accession:
GSE134321
ID:
200134321
10.

Candida auris infection of human whole blood

(Submitter supplied) To mimic the initial phases of systemic Candida infections with dissemination via the bloodstream, we used an ex vivo whole blood infection model. Dual TP of C. auris in blood gave insights into fungal adaptations and survival mechanisms as well as the host response to the infection.
Organism:
Candidozyma auris; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30319
18 Samples
Download data: CSV
Series
Accession:
GSE179000
ID:
200179000
11.

Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans

(Submitter supplied) Abstract: Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CUG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence properties of C. parapsilosis, a pathogen particularly associated with infections of premature neonates. We describe here the construction of >200 C. parapsilosis strains carrying double allele deletions of transcription factors, protein kinases and species-specific genes. more...
Organism:
Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18663
24 Samples
Download data: TXT
Series
Accession:
GSE57451
ID:
200057451
12.

A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: the transcription factor CgTog1

(Submitter supplied) The goals of this study are to compare C. glabrata transcriptome profiling (RNA-seq) upon exposure to hydrogen peroxide in order to assess the correspondent response. The role of the transcription factor Tog1 is clarified through comparison of the transcrptome profiles of WT and Tog1 mutant cells. mRNA profiles of WT and ∆tog1 were generated by deep sequencing, in duplicate, using Illumina HiSeq. The sequence reads that passed quality filters were analyzed with TopHat followed by HTSeq. more...
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26394
8 Samples
Download data: TXT
Series
Accession:
GSE148288
ID:
200148288
13.

Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida parapsilosis; Candida albicans
Type:
Expression profiling by array
Platforms:
GPL13192 GPL10903
18 Samples
Download data: GPR
Series
Accession:
GSE33490
ID:
200033490
14.

Transcriptional profile of Candida parapsilosis CLIB214 culture in low iron conditions

(Submitter supplied) Whole genome microarrays were used to generate the transcriptional profile of Candida parapsilosis in low iron conditions
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
7 Samples
Download data: GPR
Series
Accession:
GSE33462
ID:
200033462
15.

Transcriptional profile of Candida parapsilosis bcr1 knockout.

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida parapsilosis bcr1 knockout to wild type cells.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
7 Samples
Download data: GPR
Series
Accession:
GSE33461
ID:
200033461
16.

Transcriptional profile of Candida albicans bcr1 knockout.

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida albicans bcr1 knockout to wild type cells.
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL10903
4 Samples
Download data: GPR
Series
Accession:
GSE33460
ID:
200033460
17.

Physiological and transcriptional response of Candida parapsilosis to exogenous tyrosol

(Submitter supplied) Tyrosol plays a key role in fungal morphogenesis and biofilm development. Also, it has a remarkable antifungal effect at supraphysiological concentrations. However, the background of the antifungal effect remains unknown, especially in the case of non-albicans Candida species such as Candida parapsilosis We examined the effect of tyrosol on the growth, adhesion, redox homeostasis, virulence, as well as on fluconazole susceptibility. more...
Organism:
Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24494
6 Samples
Download data: XLSX
Series
Accession:
GSE129372
ID:
200129372
18.

Combined transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida albicans; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL6885 GPL22078 GPL6887
80 Samples
Download data: GPR
Series
Accession:
GSE83682
ID:
200083682
19.

Combined transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions [mouse tissues 8 h]

(Submitter supplied) The opportunistic fungal pathogen Candida albicans is a common cause of life-threatening nosocomial bloodstream infections. In the murine model of systemic candidiasis the kidney is the primary target organ while the fungal load declines over time in liver and spleen. To get a better understanding of the organ-specific differences in host-pathogen interaction during systemic murine candidiasis, we performed a time-course gene expression profiling to investigate the differential responses of murine kidney, liver and spleen and determined the fungal transcriptome in liver and kidney. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
9 Samples
Download data: TXT
Series
Accession:
GSE83681
ID:
200083681
20.

Combined transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions [mouse tissues 12,24,72 h]

(Submitter supplied) The opportunistic fungal pathogen Candida albicans is a common cause of life-threatening nosocomial bloodstream infections. In the murine model of systemic candidiasis the kidney is the primary target organ while the fungal load declines over time in liver and spleen. To get a better understanding of the organ-specific differences in host-pathogen interaction during systemic murine candidiasis, we performed a time-course gene expression profiling to investigate the differential responses of murine kidney, liver and spleen and determined the fungal transcriptome in liver and kidney. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
54 Samples
Download data: TXT
Series
Accession:
GSE83680
ID:
200083680
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