GEO DataSets

(Submitter supplied) Candida parapsilosis has emerged as a frequent cause of invasive candidiasis with increasing evidence of unique biological features relative to C. albicans. As it adapts to conditions within a mammalian host, rapid changes in gene expression are necessary to facilitate colonization and persistence in this environment. Adhesion of the organism to biological surfaces is a key first step in this process and is the focus of this study. more...

Organism:

Candida parapsilosis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18663

27 Samples

Download data: TXT

(Submitter supplied) Tyrosol plays a key role in fungal morphogenesis and biofilm development. Also, it has a remarkable antifungal effect at supraphysiological concentrations. However, the background of the antifungal effect remains unknown, especially in the case of non-albicans Candida species such as Candida parapsilosis We examined the effect of tyrosol on the growth, adhesion, redox homeostasis, virulence, as well as on fluconazole susceptibility. more...

Organism:

Candida parapsilosis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24494

6 Samples

Download data: XLSX

(Submitter supplied) Candidiasis affects a wide variety of immunocompromised individuals, including HIV/AIDS patients and cancer patients on chemotherapy. Candida albicans, a major human fungal pathogen, accounts for about 50% of all cases, while the remainder are caused by the less pathogenic non-albicans Candida species (NACS). These species are believed to be less pathogenic, in part, because they do not filament as readily or robustly as C. more...

Organism:

Candida tropicalis; Candida parapsilosis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL21876 GPL18663

16 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Candida parapsilosis; Candida albicans

Type:

Expression profiling by array

Platforms:

GPL13192 GPL10903

18 Samples

Download data: GPR

(Submitter supplied) Whole genome microarrays were used to generate the transcriptional profile of Candida parapsilosis in low iron conditions

Organism:

Candida parapsilosis

Type:

Expression profiling by array

Platform:

GPL13192

7 Samples

Download data: GPR

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida parapsilosis bcr1 knockout to wild type cells.

Organism:

Candida parapsilosis

Type:

Expression profiling by array

Platform:

GPL13192

7 Samples

Download data: GPR

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida albicans bcr1 knockout to wild type cells.

Organism:

Candida albicans

Type:

Expression profiling by array

Platform:

GPL10903

4 Samples

Download data: GPR

(Submitter supplied) Investigation of the role of HAC1 using transcriptional profiling of Candida parapsilosis treated with 5 mM dithiothreitol Gene expression of wild type and hac1 deletion strains were compared during growth in YPD only and growth in YPD with 5 mM DTT

Organism:

Candida parapsilosis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25585

12 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Candida albicans; Candida parapsilosis; Candida tropicalis; Nakaseomyces glabratus; Homo sapiens

Type:

Expression profiling by high throughput sequencing

5 related Platforms

75 Samples

Download data

(Submitter supplied) RNA extracted at 240min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16791

3 Samples

Download data: CSV

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida tropicalis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida tropicalis gene expression.

Organism:

Homo sapiens; Candida tropicalis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24977

18 Samples

Download data: CSV

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida parapsilosis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Homo sapiens gene expression.

Organism:

Candida parapsilosis; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24976

18 Samples

Download data: CSV

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida glabrata. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida glabrata gene expression.

Organism:

Nakaseomyces glabratus; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24975

18 Samples

Download data: CSV

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida albicans SC5314. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.

Organism:

Homo sapiens; Candida albicans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24974

18 Samples

Download data: CSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Candida parapsilosis

Type:

Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:

GPL13192 GPL14718

34 Samples

Download data: GPR, SAM

(Submitter supplied) We used next generation sequencing (RNA-seq) to determine the transcriptional profile of C. parapsilosis growing in several conditions including different media, temperatures and oxygen concentrations.

Organism:

Candida parapsilosis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14718

26 Samples

Download data: SAM

(Submitter supplied) Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis UPC2 delete in hypoxia.

Organism:

Candida parapsilosis

Type:

Expression profiling by array

Platform:

GPL13192

4 Samples

Download data: GPR

(Submitter supplied) Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis in hypoxic condition.

Organism:

Candida parapsilosis

Type:

Expression profiling by array

Platform:

GPL13192

4 Samples

Download data: GPR

(Submitter supplied) Invasion of host tissue by the human fungal pathogen, Candida albicans is an important step during many forms of candidosis. However, not all C. albicans strains possess the same invasive and virulence properties. It is known for example that the two clinical isolates SC5314 and ATCC10231 differ in their ability to invade into host tissue and to cause infections. Strain SC5314 is invasive whereas strain ATCC10231 is non-invasive and strongly attenuated in virulence as compared to SC5314. more...

Organism:

Candida albicans

Type:

Genome variation profiling by array

Platform:

GPL6453

2 Samples

Download data: GPR

(Submitter supplied) The opportunistic pathogenic fungus Candida albicans can cause devastating infections in severely compromised patients. Its ability to undergo a morphogenetic transition from yeast to filamentous forms allows it to penetrate tissues and cause damage, and the expression of a number of pathogenetic mechanisms are also coordinately regulated with this yeast-to-hyphae conversion. Therefore, it is widely considered that filamentation represents one of the main virulence factors of C. more...

Organism:

Candida albicans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15645

6 Samples

Download data: CSV, TXT