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Recurrent Malignant Germ Cell Tumor

MedGen UID:
1389581
•Concept ID:
C4331228
•
Neoplastic Process
Synonyms: Recurrent Germ Cell Neoplasm; Recurrent Germ Cell Tumor

Definition

The reemergence of a malignant germ cell tumor after a period of remission. [from NCI]

Professional guidelines

PubMed

Levels of beta-human chorionic gonadotropin in cerebrospinal fluid of patients with malignant germ cell tumor can be used to detect early recurrence and monitor the response to treatment.
Fujimaki T, Mishima K, Asai A, Tabuchi K, Kobayashi M, Suzuki I, Kirino T
Jpn J Clin Oncol 2000 Jul;30(7):291-4. doi: 10.1093/jjco/hyd076. PMID: 11007160

Recent clinical studies

Etiology

Successful treatment of metastatic βHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma.
Cardellicchio S, Farina S, Buccoliero AM, Agresti B, Genitori L, de Martino M, Fangusaro J, Sardi I
Eur J Pediatr 2014 Aug;173(8):1011-5. Epub 2014 Feb 21 doi: 10.1007/s00431-014-2282-x. PMID: 24556730

Diagnosis

Successful treatment of metastatic βHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma.
Cardellicchio S, Farina S, Buccoliero AM, Agresti B, Genitori L, de Martino M, Fangusaro J, Sardi I
Eur J Pediatr 2014 Aug;173(8):1011-5. Epub 2014 Feb 21 doi: 10.1007/s00431-014-2282-x. PMID: 24556730
Levels of beta-human chorionic gonadotropin in cerebrospinal fluid of patients with malignant germ cell tumor can be used to detect early recurrence and monitor the response to treatment.
Fujimaki T, Mishima K, Asai A, Tabuchi K, Kobayashi M, Suzuki I, Kirino T
Jpn J Clin Oncol 2000 Jul;30(7):291-4. doi: 10.1093/jjco/hyd076. PMID: 11007160

Therapy

Successful treatment of metastatic βHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma.
Cardellicchio S, Farina S, Buccoliero AM, Agresti B, Genitori L, de Martino M, Fangusaro J, Sardi I
Eur J Pediatr 2014 Aug;173(8):1011-5. Epub 2014 Feb 21 doi: 10.1007/s00431-014-2282-x. PMID: 24556730

Prognosis

Levels of beta-human chorionic gonadotropin in cerebrospinal fluid of patients with malignant germ cell tumor can be used to detect early recurrence and monitor the response to treatment.
Fujimaki T, Mishima K, Asai A, Tabuchi K, Kobayashi M, Suzuki I, Kirino T
Jpn J Clin Oncol 2000 Jul;30(7):291-4. doi: 10.1093/jjco/hyd076. PMID: 11007160

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