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Recurrent Primary Central Nervous System Neoplasm

MedGen UID:: 1711499
•Concept ID:: C5239394
•: Neoplastic Process

Synonym:

Recurrent Primary Central Nervous System Tumor

Definition

The reemergence of a primary central nervous system neoplasm after a period of remission. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRecurrent Primary Central Nervous System Neoplasm

Disease
- Disorder by Site
  - Disorder of nervous system
    - Disorder of the central nervous system
      - Neoplasm of the central nervous system
        Primary Central Nervous System Neoplasm
        Recurrent Primary Central Nervous System Neoplasm
        Recurrent Childhood Central Nervous System Neoplasm
        Recurrent Childhood Anaplastic Oligoastrocytoma
        Recurrent Childhood Anaplastic Oligodendroglioma
        Recurrent Childhood Astrocytic Tumor
        Recurrent Childhood Anaplastic Astrocytoma
        Recurrent Childhood Brain Stem Astrocytoma
        Recurrent Childhood Cerebellar Astrocytoma
        Recurrent Childhood Cerebral Astrocytoma
        Recurrent Childhood Diffuse Astrocytoma
        Recurrent Childhood Glioblastoma
        Recurrent Childhood Pilocytic Astrocytoma
        Recurrent Childhood Pilomyxoid Astrocytoma
        Recurrent Childhood Pleomorphic Xanthoastrocytoma
        Recurrent Childhood Subependymal Giant Cell Astrocytoma
        Recurrent Childhood Visual Pathway Astrocytoma
        Recurrent Childhood Brain Neoplasm
        Recurrent Childhood Brain Stem Glioma
        Recurrent Childhood Gliomatosis Cerebri
        Recurrent Childhood Medulloblastoma
        Recurrent Childhood Pineoblastoma
        Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified
        Recurrent Childhood Visual Pathway Glioma
        Recurrent Childhood Central Nervous System Embryonal Neoplasm
        Recurrent Childhood Ependymoma
        Recurrent Childhood Oligoastrocytoma
        Recurrent Childhood Oligodendroglioma
        Recurrent Childhood Spinal Cord Neoplasm
        Recurrent Gangliocytoma
        Recurrent Glioma
        Recurrent Ependymal Tumor
        Recurrent Anaplastic Ependymoma
        Recurrent Ependymoma
        Recurrent Low Grade Glioma
        Recurrent Low Grade Astrocytoma
        Recurrent WHO Grade 1 Glioma
        Recurrent WHO Grade 2 Glioma
        Recurrent Malignant Glioma
        Recurrent Diffuse Intrinsic Pontine Glioma
        Recurrent Diffuse Midline Glioma, H3 K27M-Mutant
        Recurrent Glioblastoma
        Recurrent WHO Grade 3 Glioma
        Recurrent Tectal Glioma
        Recurrent Visual Pathway Glioma
        Recurrent Intracranial Neoplasm
        Recurrent Brain Neoplasm
        Recurrent Adult Brain Neoplasm
        Recurrent Craniopharyngioma
        Recurrent Malignant Brain Neoplasm
        Recurrent Multinodular and Vacuolated Neuronal Tumor
        Recurrent Pineal Parenchymal Cell Neoplasm
        Recurrent Meningioma
        Recurrent Anaplastic (Malignant) Meningioma
        Recurrent Atypical Meningioma
        Recurrent Myxoid Glioneuronal Tumor
        Recurrent Polymorphous Low Grade Neuroepithelial Tumor of the Young
        Recurrent Primary Malignant Central Nervous System Neoplasm
        Recurrent Anaplastic Ganglioglioma
        Recurrent Atypical Teratoid/Rhabdoid Tumor
        Recurrent Central Nervous System Lymphoma
        Recurrent Central Nervous System Non-Hodgkin Lymphoma
        Recurrent Retinoblastoma
        Recurrent Spinal Cord Neoplasm
        Recurrent Adult Spinal Cord Neoplasm

Professional guidelines

PubMed

Primary central nervous system lymphoma.

Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012 Free PMC Article

EANO guideline on the diagnosis and management of meningiomas.

Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

See all (2127)

Recent clinical studies

Etiology

How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia.

Kopmar NE, Cassaday RD
Blood 2023 Mar 23;141(12):1379-1388. doi: 10.1182/blood.2022017035. PMID: 36548957 Free PMC Article

Prevention and management of secondary central nervous system lymphoma.

Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246 Free PMC Article

Central Nervous System Involvement in Adults with Acute Leukemia: Diagnosis, Prevention, and Management.

Paul S, Short NJ
Curr Oncol Rep 2022 Apr;24(4):427-436. Epub 2022 Feb 10 doi: 10.1007/s11912-022-01220-4. PMID: 35141858

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

See all (10822)

Diagnosis

Primary central nervous system lymphoma.

How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia.

Kopmar NE, Cassaday RD
Blood 2023 Mar 23;141(12):1379-1388. doi: 10.1182/blood.2022017035. PMID: 36548957 Free PMC Article

Prevention and management of secondary central nervous system lymphoma.

Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246 Free PMC Article

Central Nervous System Involvement in Adults with Acute Leukemia: Diagnosis, Prevention, and Management.

Paul S, Short NJ
Curr Oncol Rep 2022 Apr;24(4):427-436. Epub 2022 Feb 10 doi: 10.1007/s11912-022-01220-4. PMID: 35141858

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

See all (10672)

Therapy

Prevention and management of secondary central nervous system lymphoma.

Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246 Free PMC Article

Treatment Options for Recurrent Primary CNS Lymphoma.

Kaulen LD, Baehring JM
Curr Treat Options Oncol 2022 Nov;23(11):1548-1565. Epub 2022 Oct 7 doi: 10.1007/s11864-022-01016-5. PMID: 36205806

CNS prophylaxis for diffuse large B-cell lymphoma.

Eyre TA, Savage KJ, Cheah CY, El-Galaly TC, Lewis KL, McKay P, Wilson MR, Evens AM, Bobillo S, Villa D, Maurer MJ, Cwynarski K, Ferreri AJM
Lancet Oncol 2022 Sep;23(9):e416-e426. doi: 10.1016/S1470-2045(22)00371-0. PMID: 36055310

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

Primary CNS Lymphoma.

Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701 Free PMC Article

See all (8110)

Prognosis

Primary central nervous system lymphoma.

Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions.

Thastrup M, Duguid A, Mirian C, Schmiegelow K, Halsey C
Leukemia 2022 Dec;36(12):2751-2768. Epub 2022 Oct 20 doi: 10.1038/s41375-022-01714-x. PMID: 36266325 Free PMC Article

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Primary CNS Lymphoma.

Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701 Free PMC Article

See all (11229)

Clinical prediction guides

How I treat secondary CNS involvement by aggressive lymphomas.

Alderuccio JP, Nayak L, Cwynarski K
Blood 2023 Nov 23;142(21):1771-1783. doi: 10.1182/blood.2023020168. PMID: 37702537 Free PMC Article

Central Nervous System Lymphoma: Novel Therapies.

Fortin Ensign SP, Gathers D, Wiedmeier JE, Mrugala MM
Curr Treat Options Oncol 2022 Jan;23(1):117-136. Epub 2022 Feb 19 doi: 10.1007/s11864-021-00921-5. PMID: 35182298

Central Nervous System Lymphomas.

Grommes C
Continuum (Minneap Minn) 2020 Dec;26(6):1476-1494. doi: 10.1212/CON.0000000000000936. PMID: 33273169

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

See all (6667)

Recent systematic reviews

Nivolumab for newly and recurrent glioblastoma multiforme treatment: A systematic review and meta-analysis.

Araujo Moura AW, da Silva Rodrigues S, de Oliveira TF, Lobato BM, Pereira Cerize NN, Léo P
J Oncol Pharm Pract 2023 Oct;29(7):1736-1747. Epub 2023 Jul 28 doi: 10.1177/10781552231190104. PMID: 37503551

Stereotactic Radiosurgery for Intracranial Primary Melanocytomas.

Dar N, Mantziaris G, Pikis S, Young L, Sheehan J
World Neurosurg 2022 Aug;164:160-166. Epub 2022 May 10 doi: 10.1016/j.wneu.2022.04.136. PMID: 35552031

Primary central nervous system sarcomas in adults: A systematic review.

Haider AS, Palmisciano P, Sagoo NS, Bin Alamer O, El Ahmadieh TY, Pan E, Garzon-Muvdi T
Clin Neurol Neurosurg 2022 Mar;214:107127. Epub 2022 Jan 12 doi: 10.1016/j.clineuro.2022.107127. PMID: 35151057

Adjuvant Therapy for Stage II Colon Cancer: ASCO Guideline Update.

Baxter NN, Kennedy EB, Bergsland E, Berlin J, George TJ, Gill S, Gold PJ, Hantel A, Jones L, Lieu C, Mahmoud N, Morris AM, Ruiz-Garcia E, You YN, Meyerhardt JA
J Clin Oncol 2022 Mar 10;40(8):892-910. Epub 2021 Dec 22 doi: 10.1200/JCO.21.02538. PMID: 34936379

Treatment options for progression or recurrence of glioblastoma: a network meta-analysis.

McBain C, Lawrie TA, Rogozińska E, Kernohan A, Robinson T, Jefferies S
Cochrane Database Syst Rev 2021 May 4;5(1):CD013579. doi: 10.1002/14651858.CD013579.pub2. PMID: 34559423 Free PMC Article

See all (370)

MedGen

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Recurrent Primary Central Nervous System Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity