U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Locally Advanced Pharyngeal Carcinoma

MedGen UID:
1716286
Concept ID:
C5237270
Neoplastic Process

Definition

Pharyngeal carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Rothschild S, Studer G, Seifert B, Huguenin P, Glanzmann C, Davis JB, Lütolf UM, Hany TF, Ciernik IF
Radiat Oncol 2007 Jun 9;2:22. doi: 10.1186/1748-717X-2-22. PMID: 17559684Free PMC Article

Recent clinical studies

Etiology

Machiels JP, Tao Y, Licitra L, Burtness B, Tahara M, Rischin D, Alves G, Lima IPF, Hughes BGM, Pointreau Y, Aksoy S, Laban S, Greil R, Burian M, Hetnał M, Delord JP, Mesía R, Taberna M, Waldron JN, Simon C, Grégoire V, Harrington KJ, Swaby RF, Zhang Y, Gumuscu B, Bidadi B, Siu LL; KEYNOTE-412 Investigators
Lancet Oncol 2024 May;25(5):572-587. Epub 2024 Mar 29 doi: 10.1016/S1470-2045(24)00100-1. PMID: 38561010
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Echanique KA, Evans LK, Han AY, Chhetri DK, St John MA
Hematol Oncol Clin North Am 2021 Oct;35(5):933-947. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.005. PMID: 34272102
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347

Diagnosis

Machiels JP, Tao Y, Licitra L, Burtness B, Tahara M, Rischin D, Alves G, Lima IPF, Hughes BGM, Pointreau Y, Aksoy S, Laban S, Greil R, Burian M, Hetnał M, Delord JP, Mesía R, Taberna M, Waldron JN, Simon C, Grégoire V, Harrington KJ, Swaby RF, Zhang Y, Gumuscu B, Bidadi B, Siu LL; KEYNOTE-412 Investigators
Lancet Oncol 2024 May;25(5):572-587. Epub 2024 Mar 29 doi: 10.1016/S1470-2045(24)00100-1. PMID: 38561010
Costantino A, Meliante PG, Sampieri C, Lee K, Ralli M, De Vincentiis M, De Virgilio A, Kim SH
Eur Arch Otorhinolaryngol 2023 Oct;280(10):4649-4655. Epub 2023 Jul 3 doi: 10.1007/s00405-023-08070-1. PMID: 37395758
Eckel HE, Bradley PJ
Adv Otorhinolaryngol 2019;83:47-53. Epub 2019 Feb 12 doi: 10.1159/000492308. PMID: 30943512
Kontny U, Franzen S, Behrends U, Bührlen M, Christiansen H, Delecluse H, Eble M, Feuchtinger T, Gademann G, Granzen B, Kratz CP, Lassay L, Leuschner I, Mottaghy FM, Schmitt C, Staatz G, Timmermann B, Vorwerk P, Wilop S, Wolff HA, Mertens R
Klin Padiatr 2016 Apr;228(3):105-12. Epub 2016 May 2 doi: 10.1055/s-0041-111180. PMID: 27135270
Wycliffe ND, Grover RS, Kim PD, Simental A Jr
Top Magn Reson Imaging 2007 Aug;18(4):243-58. doi: 10.1097/RMR.0b013e3181570c3f. PMID: 17893590

Therapy

Machiels JP, Tao Y, Licitra L, Burtness B, Tahara M, Rischin D, Alves G, Lima IPF, Hughes BGM, Pointreau Y, Aksoy S, Laban S, Greil R, Burian M, Hetnał M, Delord JP, Mesía R, Taberna M, Waldron JN, Simon C, Grégoire V, Harrington KJ, Swaby RF, Zhang Y, Gumuscu B, Bidadi B, Siu LL; KEYNOTE-412 Investigators
Lancet Oncol 2024 May;25(5):572-587. Epub 2024 Mar 29 doi: 10.1016/S1470-2045(24)00100-1. PMID: 38561010
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Echanique KA, Evans LK, Han AY, Chhetri DK, St John MA
Hematol Oncol Clin North Am 2021 Oct;35(5):933-947. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.005. PMID: 34272102
Eckel HE, Bradley PJ
Adv Otorhinolaryngol 2019;83:47-53. Epub 2019 Feb 12 doi: 10.1159/000492308. PMID: 30943512
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347

Prognosis

Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Saba NF, Salama JK, Beitler JJ, Busse PM, Cooper JS, Jones CU, Koyfman S, Quon H, Ridge JA, Siddiqui F, Worden F, Yao M, Yom SS; Expert Panel on Radiation Oncology-Head and Neck Cancer
Head Neck 2016 Jul;38(7):979-86. Epub 2016 Apr 30 doi: 10.1002/hed.24423. PMID: 27131050
Dillon MT, Harrington KJ
J Clin Oncol 2015 Oct 10;33(29):3251-61. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7804. PMID: 26351347
Wycliffe ND, Grover RS, Kim PD, Simental A Jr
Top Magn Reson Imaging 2007 Aug;18(4):243-58. doi: 10.1097/RMR.0b013e3181570c3f. PMID: 17893590
Archibald S, Young JE, Thoma A
Clin Plast Surg 2005 Jul;32(3):339-46, vi. doi: 10.1016/j.cps.2005.01.002. PMID: 15979473

Clinical prediction guides

Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Yang Z, Zuo Q, Liu R, Wu H, Xiong L, Jia J, Xiang Z
BMC Cancer 2023 Nov 24;23(1):1140. doi: 10.1186/s12885-023-11608-5. PMID: 37996813Free PMC Article
Costantino A, Meliante PG, Sampieri C, Lee K, Ralli M, De Vincentiis M, De Virgilio A, Kim SH
Eur Arch Otorhinolaryngol 2023 Oct;280(10):4649-4655. Epub 2023 Jul 3 doi: 10.1007/s00405-023-08070-1. PMID: 37395758
Liouta G, Adamaki M, Tsintarakis A, Zoumpourlis P, Liouta A, Agelaki S, Zoumpourlis V
Int J Mol Sci 2023 Feb 3;24(3) doi: 10.3390/ijms24032996. PMID: 36769317Free PMC Article
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Dutta S, Midyett FA, Barloon J, Sallah S
Ann Oncol 2004 Mar;15(3):383-8. doi: 10.1093/annonc/mdh101. PMID: 14998839

Recent systematic reviews

Kamal F, Khan MA, Lee-Smith W, Sharma S, Imam Z, Jowhar D, Petryna E, Esswein J, Acharya A, Aziz M, Farooq U, Zafar U, Mcdonough S, Adler DG
Dig Dis Sci 2022 Aug;67(8):3518-3528. Epub 2021 Sep 9 doi: 10.1007/s10620-021-07225-6. PMID: 34505257
De Virgilio A, Russo E, Costantino A, Malvezzi L, Colombo G, Cugini G, Miceli S, Rossi V, Spriano G, Mercante G
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2663-2672. Epub 2020 May 2 doi: 10.1007/s00405-020-05990-0. PMID: 32361771

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...