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Chondroma

MedGen UID:
181701
•Concept ID:
C0936248
•
Neoplastic Process
Synonym: Chondromas
SNOMED CT: Chondroma (31186001)
 
Monarch Initiative: MONDO:0002360

Definition

A benign well circumscribed neoplasm of hyaline cartilage arising from bone or soft tissue. It is characterized by the presence of chondrocytes. [from NCI]

Professional guidelines

PubMed

The Application of Arthroscopic Techniques in the Diagnosis and Treatment of Hip-Related Conditions in China.
Zhao FY, Dong HM, Huang HJ, Gao GY, Wu RQ, Shi YY, Ju XD, Li CB, Xu Y, Wang JQ
Orthop Surg 2021 Aug;13(6):1697-1706. Epub 2021 Aug 5 doi: 10.1111/os.13043. PMID: 34351067Free PMC Article
Strategies of treatment of chest wall tumors and our experience.
Chudacek J, Bohanes T, Szkorupa M, Klein J, Stasek M, Zalesak B, Stehlik D, Ctvrtlík F, Neoral C
Rozhl Chir 2015 Jan;94(1):17-23. PMID: 25604980
Thoracic surgical operations performed under local anesthesia and sedation for diagnosis and treatment.
Solak O, Cuhadaroglu S, Sayar A, Turna A, Metin M, Esme H, Gurses A
Thorac Cardiovasc Surg 2007 Jun;55(4):245-8. doi: 10.1055/s-2006-955959. PMID: 17546555

Recent clinical studies

Etiology

The distribution of chondromas: Why the hand?
Nazarova NZ, Umarova GS, Vaiman M, Abba M, Foonberg M, Mametov K, Shterenshis M
Med Hypotheses 2020 Oct;143:110132. Epub 2020 Jul 23 doi: 10.1016/j.mehy.2020.110132. PMID: 32759011
Cartilage-forming tumors.
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178
Gastrointestinal stromal tumour.
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959
Extraskeletal chondromas.
Marcial-Seoane RA, Marcial-Seoane MA, Ramos E, Marcial-Rojas RA
Bol Asoc Med P R 1990 Sep;82(9):394-402. PMID: 2076144

Diagnosis

Benign Cartilage-forming Tumors.
Kerr DA, Cipriani NA
Surg Pathol Clin 2021 Dec;14(4):585-603. Epub 2021 Oct 7 doi: 10.1016/j.path.2021.06.004. PMID: 34742482
Solitary enchondromas-diagnosis and surveillance : Danish guidelines.
Jurik AG, Hansen BH, Weber K
Radiologe 2020 Nov;60(Suppl 1):26-32. doi: 10.1007/s00117-020-00681-7. PMID: 32322923
Endobronchial chondromas.
Fernandez-Bussy S, Labarca G, Descalzi F, Pires Y, Santos M, Folch E, Majid A
Respir Care 2014 Dec;59(12):e193-6. Epub 2014 Jul 15 doi: 10.4187/respcare.02673. PMID: 25233382
Cartilage-forming tumors.
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178
Chondroma and chondrosarcoma.
Somers J, Faber LP
Semin Thorac Cardiovasc Surg 1999 Jul;11(3):270-7. doi: 10.1016/s1043-0679(99)70068-7. PMID: 10451259

Therapy

Impact of Patient and Tumor Characteristics on Range of Motion and Recurrence Following Treatment of Enchondromas of the Hand.
Wessel LE, Christ AB, Athanasian EA
J Hand Surg Am 2023 May;48(5):512.e1-512.e7. Epub 2022 Jan 31 doi: 10.1016/j.jhsa.2021.11.027. PMID: 35115192
Limitations of Transoral Robotic Total Laryngectomy.
Chebib E, Lechien JR, Chekkoury-Idrissi Y, Circiu MP, Distinguin L, Pouliquen C, Hans S
J Voice 2021 Sep;35(5):681-682. Epub 2020 Dec 15 doi: 10.1016/j.jvoice.2020.12.004. PMID: 33339704
Gastrointestinal stromal tumour.
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group.
Tallini G, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Sciot R, Van den Berghe H, Vanni R, Willén H
J Pathol 2002 Feb;196(2):194-203. doi: 10.1002/path.1023. PMID: 11793371
Complications of radiation therapy.
Dalinka MK, Mazzeo VP Jr
Crit Rev Diagn Imaging 1985;23(3):235-67. PMID: 3891233

Prognosis

Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors.
Ibrahim A, Chopra S
Arch Pathol Lab Med 2020 May;144(5):655-660. Epub 2019 Jun 6 doi: 10.5858/arpa.2018-0370-RS. PMID: 31169996
Common Tumors and Tumor-like Lesions of the Shoulder.
Lee DH, Hills JM, Jordanov MI, Jaffe KA
J Am Acad Orthop Surg 2019 Apr 1;27(7):236-245. doi: 10.5435/JAAOS-D-17-00449. PMID: 30320728
Imaging pediatric gastrointestinal stromal tumor (GIST).
Herzberg M, Beer M, Anupindi S, Vollert K, Kröncke T
J Pediatr Surg 2018 Sep;53(9):1862-1870. Epub 2018 Mar 29 doi: 10.1016/j.jpedsurg.2018.03.022. PMID: 29685489
Succinate dehydrogenase (SDH)-deficient neoplasia.
Gill AJ
Histopathology 2018 Jan;72(1):106-116. doi: 10.1111/his.13277. PMID: 29239034
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

Clinical prediction guides

Benign Cartilage-forming Tumors.
Kerr DA, Cipriani NA
Surg Pathol Clin 2021 Dec;14(4):585-603. Epub 2021 Oct 7 doi: 10.1016/j.path.2021.06.004. PMID: 34742482
Solitary enchondromas-diagnosis and surveillance : Danish guidelines.
Jurik AG, Hansen BH, Weber K
Radiologe 2020 Nov;60(Suppl 1):26-32. doi: 10.1007/s00117-020-00681-7. PMID: 32322923
Chondroma of the Tongue.
Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089
Succinate dehydrogenase (SDH)-deficient neoplasia.
Gill AJ
Histopathology 2018 Jan;72(1):106-116. doi: 10.1111/his.13277. PMID: 29239034
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

Recent systematic reviews

A Systematic Review of Cavernous Sinus Chondromas and an Illustrative Case Treated With Subtotal Resection Followed by Gamma Knife Radiosurgery.
Demir MK, Yapıcıer O, Ertem O, Paker B, Zorlu E, Kılıc T
World Neurosurg 2023 Aug;176:66-73. Epub 2023 Apr 26 doi: 10.1016/j.wneu.2023.04.079. PMID: 37116785
Can MRI differentiate between atypical cartilaginous tumors and high-grade chondrosarcoma? A systematic review.
Deckers C, Steyvers MJ, Hannink G, Schreuder HWB, de Rooy JWJ, Van Der Geest ICM
Acta Orthop 2020 Aug;91(4):471-478. Epub 2020 May 20 doi: 10.1080/17453674.2020.1763717. PMID: 32429792Free PMC Article
Intracranial Dural Parafalcine Chondroma: Case Report and Systematic Review of the Literature.
Sullivan JC, Goldsmith J, Rojas R, Varma H, Kasper EM
World Neurosurg 2019 Feb;122:1-7. Epub 2018 Sep 29 doi: 10.1016/j.wneu.2018.09.169. PMID: 30273721
Imaging pediatric gastrointestinal stromal tumor (GIST).
Herzberg M, Beer M, Anupindi S, Vollert K, Kröncke T
J Pediatr Surg 2018 Sep;53(9):1862-1870. Epub 2018 Mar 29 doi: 10.1016/j.jpedsurg.2018.03.022. PMID: 29685489
F-18 FDG PET differentiation of benign from malignant chondroid neoplasms: a systematic review of the literature.
Subhawong TK, Winn A, Shemesh SS, Pretell-Mazzini J
Skeletal Radiol 2017 Sep;46(9):1233-1239. Epub 2017 Jun 12 doi: 10.1007/s00256-017-2685-7. PMID: 28608242

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