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Malignant renal pelvis neoplasm

MedGen UID:
57793
•Concept ID:
C0153618
•
Neoplastic Process
Synonyms: cancer of renal pelvis; Malignant Neoplasm of Renal Pelvis; malignant neoplasm of renal pelvis; Malignant Neoplasm of the Renal Pelvis; malignant neoplasm of the renal pelvis; Malignant Renal Pelvis Neoplasm; malignant renal pelvis neoplasm; Malignant Renal Pelvis Tumor; malignant renal pelvis tumor; malignant renal pelvis tumour; Malignant tumor of renal pelvis; Malignant Tumor of Renal Pelvis; malignant tumor of renal pelvis; Malignant Tumor of the Renal Pelvis; malignant tumor of the renal pelvis; malignant tumour of renal pelvis; malignant tumour of the renal pelvis; renal pelvis cancer
SNOMED CT: Malignant tumor of renal pelvis (363457009)
 
Monarch Initiative: MONDO:0044919

Definition

A primary or metastatic malignant neoplasm that affects the renal pelvis. [from NCI]

Professional guidelines

PubMed

Diagnosis and Management of Non-Metastatic Upper Tract Urothelial Carcinoma: AUA/SUO Guideline.
Coleman JA, Clark PE, Bixler BR, Buckley DI, Chang SS, Chou R, Hoffman-Censits J, Kulkarni GS, Matin SF, Pierorazio PM, Potretzke AM, Psutka SP, Raman JD, Smith AB, Smith L
J Urol 2023 Jun;209(6):1071-1081. Epub 2023 Apr 25 doi: 10.1097/JU.0000000000003480. PMID: 37096584
Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530

Recent clinical studies

Etiology

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Contrast-Enhanced Ultrasound Characteristics of Renal Pelvis Urothelial Carcinoma and Its Relationship with Microvessel Density.
Zhang B, Li J, Wu Z, Li C, Sun T, Zhuo N, Liang J, Duan Q, Hu H, Tian J
Ultrasound Med Biol 2021 Feb;47(2):236-243. Epub 2020 Nov 4 doi: 10.1016/j.ultrasmedbio.2020.09.006. PMID: 33158635
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611

Diagnosis

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Analysis of genetic profiling, pathomics signature, and prognostic features of primary lymphoepithelioma-like carcinoma of the renal pelvis.
Fan B, Huang Y, Zhang H, Chen T, Tao S, Wang X, Wen S, Wang H, Lin Z, Liu T, Zhang H, He T, Li X
Mol Oncol 2022 Oct;16(20):3666-3688. Epub 2022 Sep 2 doi: 10.1002/1878-0261.13307. PMID: 36052737Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Urothelial cancers: ureter, renal pelvis, and bladder.
Tyler A
Semin Oncol Nurs 2012 Aug;28(3):154-62. doi: 10.1016/j.soncn.2012.05.004. PMID: 22846483
Pyeloduodenocolic fistula.
Poon JT, Tam PC, Chu KM
Asian J Surg 2003 Jul;26(3):186-8. doi: 10.1016/S1015-9584(09)60382-1. PMID: 12925297

Therapy

Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Lymphangioleiomyomatosis.
Johnson SR, Taveira-DaSilva AM, Moss J
Clin Chest Med 2016 Sep;37(3):389-403. doi: 10.1016/j.ccm.2016.04.002. PMID: 27514586
Epidemiology and risk factors for kidney cancer.
Chow WH, Dong LM, Devesa SS
Nat Rev Urol 2010 May;7(5):245-57. doi: 10.1038/nrurol.2010.46. PMID: 20448658Free PMC Article
Tobacco smoking and cancer: a brief review of recent epidemiological evidence.
Sasco AJ, Secretan MB, Straif K
Lung Cancer 2004 Aug;45 Suppl 2:S3-9. doi: 10.1016/j.lungcan.2004.07.998. PMID: 15552776
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Analysis of genetic profiling, pathomics signature, and prognostic features of primary lymphoepithelioma-like carcinoma of the renal pelvis.
Fan B, Huang Y, Zhang H, Chen T, Tao S, Wang X, Wen S, Wang H, Lin Z, Liu T, Zhang H, He T, Li X
Mol Oncol 2022 Oct;16(20):3666-3688. Epub 2022 Sep 2 doi: 10.1002/1878-0261.13307. PMID: 36052737Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Occupation and risk of cancer of the renal pelvis in Nordic countries.
Michalek IM, Martinsen JI, Weiderpass E, Kjaerheim K, Lynge E, Sparen P, Tryggvadottir L, Pukkala E
BJU Int 2019 Feb;123(2):233-238. Epub 2018 Oct 3 doi: 10.1111/bju.14533. PMID: 30216629
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375

Clinical prediction guides

A Large Genetic Causal Analysis of the Gut Microbiota and Urological Cancers: A Bidirectional Mendelian Randomization Study.
Yin Z, Liu B, Feng S, He Y, Tang C, Chen P, Wang X, Wang K
Nutrients 2023 Sep 21;15(18) doi: 10.3390/nu15184086. PMID: 37764869Free PMC Article
Analysis of genetic profiling, pathomics signature, and prognostic features of primary lymphoepithelioma-like carcinoma of the renal pelvis.
Fan B, Huang Y, Zhang H, Chen T, Tao S, Wang X, Wen S, Wang H, Lin Z, Liu T, Zhang H, He T, Li X
Mol Oncol 2022 Oct;16(20):3666-3688. Epub 2022 Sep 2 doi: 10.1002/1878-0261.13307. PMID: 36052737Free PMC Article
Contrast-Enhanced Ultrasound Characteristics of Renal Pelvis Urothelial Carcinoma and Its Relationship with Microvessel Density.
Zhang B, Li J, Wu Z, Li C, Sun T, Zhuo N, Liang J, Duan Q, Hu H, Tian J
Ultrasound Med Biol 2021 Feb;47(2):236-243. Epub 2020 Nov 4 doi: 10.1016/j.ultrasmedbio.2020.09.006. PMID: 33158635
Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375

Recent systematic reviews

Ectopic insulinoma: a systematic review.
Guerrero-Pérez F, Vilarrasa N, Huánuco LV, Busquets J, Secanella L, Vercher-Conejero JL, Vidal N, Näf Cortés S, Villabona C
Rev Endocr Metab Disord 2023 Dec;24(6):1135-1146. Epub 2023 Jul 12 doi: 10.1007/s11154-023-09824-2. PMID: 37434098
Adverse Events of Immune Checkpoint Inhibitors Therapy for Urologic Cancer Patients in Clinical Trials: A Collaborative Systematic Review and Meta-analysis.
Wu Z, Chen Q, Qu L, Li M, Wang L, Mir MC, Carbonara U, Pandolfo SD, Black PC, Paul AK, Di Lorenzo G, Porpiglia F, Mari A, Necchi A, Rouprêt M, Psutka SP, Autorino R
Eur Urol 2022 Apr;81(4):414-425. Epub 2022 Jan 31 doi: 10.1016/j.eururo.2022.01.028. PMID: 35101302
The endovascular management of neurofibromatosis-associated aneurysms: A systematic review.
Bargiela D, Verkerk MM, Wee I, Welman K, Ng E, Choong AMTL
Eur J Radiol 2018 Mar;100:66-75. Epub 2017 Dec 23 doi: 10.1016/j.ejrad.2017.12.014. PMID: 29496081
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375

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