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Heart block

MedGen UID:
42363
•Concept ID:
C0018794
•
Disease or Syndrome; Finding
Synonyms: Block, Heart; Blocks, Heart; Heart Block; Heart Blocks
SNOMED CT: Heart block (233916004); HB - Heart block (233916004)
 
HPO: HP:0012722

Definition

Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHeart block

Conditions with this feature

Meier-Gorlin syndrome 7
MedGen UID:
934705
•Concept ID:
C4310738
•
Disease or Syndrome
Any Meier-Gorlin syndrome in which the cause of the disease is a mutation in the CDC45 gene.
See: Condition Record
Meier-Gorlin syndrome 7

Professional guidelines

PubMed

Fetal Arrhythmia Diagnosis and Pharmacologic Management.
Strasburger JF, Eckstein G, Butler M, Noffke P, Wacker-Gussmann A
J Clin Pharmacol 2022 Sep;62 Suppl 1(Suppl 1):S53-S66. doi: 10.1002/jcph.2129. PMID: 36106782Free PMC Article
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772
HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis.
Birnie DH, Sauer WH, Bogun F, Cooper JM, Culver DA, Duvernoy CS, Judson MA, Kron J, Mehta D, Cosedis Nielsen J, Patel AR, Ohe T, Raatikainen P, Soejima K
Heart Rhythm 2014 Jul;11(7):1305-23. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.03.043. PMID: 24819193

Recent clinical studies

Etiology

Congenital Heart Block.
Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Congenital Heart Block.
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Third-degree heart block associated with lyme carditis: review of published cases.
Forrester JD, Mead P
Clin Infect Dis 2014 Oct;59(7):996-1000. Epub 2014 May 30 doi: 10.1093/cid/ciu411. PMID: 24879781
Cardiac manifestations of systemic lupus erythematosus.
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Neonatal lupus syndrome.
Olson NY, Lindsley CB
Am J Dis Child 1987 Aug;141(8):908-10. doi: 10.1001/archpedi.1987.04460080094037. PMID: 3307387

Diagnosis

Congenital Heart Block.
Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Congenital Heart Block.
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Heart block after herpes zoster reactivation.
Kalender E, Şensoy B, Çay S
Int J Cardiol 2016 Jan 15;203:549-50. Epub 2015 Oct 28 doi: 10.1016/j.ijcard.2015.10.163. PMID: 26569360
Atrioventricular block revisited.
Barold SS
Compr Ther 2002 Spring;28(1):74-8. doi: 10.1007/s12019-002-0044-6. PMID: 11894446
Atrioventricular block.
Cross JA
AACN Clin Issues Crit Care Nurs 1992 Feb;3(1):166-72. doi: 10.4037/15597768-1992-1021. PMID: 1554557

Therapy

Electrocautery-Induced Complete Heart Block.
Alghanem H, Patoli D, Greenberg SB, Szokol JW, Silk VL
J Cardiothorac Vasc Anesth 2021 Jul;35(7):2230-2232. Epub 2020 Nov 10 doi: 10.1053/j.jvca.2020.11.018. PMID: 33268040
Mitral Annulus Calcium Score.
Brodov Y, Konen E, Di Segni M, Samoocha D, Chernomordik F, Barbash I, Regev E, Raanani E, Guetta V, Segev A, Fefer P, Glikson M, Goitein O
Circ Cardiovasc Imaging 2019 Dec;12(1):e007508. doi: 10.1161/CIRCIMAGING.117.007508. PMID: 30636515
Should we treat congenital heart block with fluorinated corticosteroids?
Brucato A, Tincani A, Fredi M, Breda S, Ramoni V, Morel N, Costedoat-Chalumeau N
Autoimmun Rev 2017 Nov;16(11):1115-1118. Epub 2017 Sep 9 doi: 10.1016/j.autrev.2017.09.005. PMID: 28899797
UKPACE: to die, or not to die ... is that the question?
Lin JC, Goldstein M, Benditt DG
Europace 2006 Oct;8(10):852-4. doi: 10.1093/europace/eul085. PMID: 17000634
Treatment of depression in patients with heart disease.
Roose SP, Spatz E
J Clin Psychiatry 1999;60 Suppl 20:34-7. PMID: 10513857

Prognosis

Atrioventricular Dissociation during Ventricular Fibrillation.
Salik JR, Thomas SS
N Engl J Med 2020 Jun 4;382(23):e84. doi: 10.1056/NEJMicm1916823. PMID: 32492307
Transcatheter aortic valve replacement and cardiac conduction.
Shreenivas S, Schloss E, Choo J, Sarembock I, Lilly S, Kereiakes D
Expert Rev Cardiovasc Ther 2019 Apr;17(4):293-304. doi: 10.1080/14779072.2019.1598264. PMID: 30912984
Cough-induced heart block.
Lee D, Beldner S, Pollaro F, Jadonath R, Maccaro P, Goldner B
Pacing Clin Electrophysiol 1999 Aug;22(8):1270-1. doi: 10.1111/j.1540-8159.1999.tb00615.x. PMID: 10461310
Congenital complete atrioventricular block.
Ross BA
Pediatr Clin North Am 1990 Feb;37(1):69-78. doi: 10.1016/s0031-3955(16)36832-8. PMID: 2408004
Sinus node arrest and sino--atrial block.
Shaw DB, Southall DP
Eur Heart J 1984 Mar;5 Suppl A:83-7. doi: 10.1093/eurheartj/5.suppl_a.83. PMID: 6373289

Clinical prediction guides

Mitral Annulus Calcium Score.
Brodov Y, Konen E, Di Segni M, Samoocha D, Chernomordik F, Barbash I, Regev E, Raanani E, Guetta V, Segev A, Fefer P, Glikson M, Goitein O
Circ Cardiovasc Imaging 2019 Dec;12(1):e007508. doi: 10.1161/CIRCIMAGING.117.007508. PMID: 30636515
Tale of 2 Orifices.
Vainrib AF, Loulmet DF, Williams MR, Saric M
Circ Cardiovasc Imaging 2019 Dec;12(1):e008372. doi: 10.1161/CIRCIMAGING.118.008372. PMID: 30636514
Cardiac manifestations of systemic lupus erythematosus.
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Cardiac sarcoid: a clinician's review on how to approach the patient with cardiac sarcoid.
Mantini N, Williams B Jr, Stewart J, Rubinsztain L, Kacharava A
Clin Cardiol 2012;35(7):410-5. Epub 2012 Apr 12 doi: 10.1002/clc.21982. PMID: 22499155Free PMC Article
Atrioventricular block.
Cross JA
AACN Clin Issues Crit Care Nurs 1992 Feb;3(1):166-72. doi: 10.4037/15597768-1992-1021. PMID: 1554557

Recent systematic reviews

Influenza associated cardiac arrhythmia- a systematic review.
Alam MM, Paul T, Aggarwal A, Zarich S
Am J Med Sci 2024 Apr;367(4):235-242. Epub 2024 Jan 5 doi: 10.1016/j.amjms.2024.01.004. PMID: 38185405
Arrhythmias Beyond Atrial Fibrillation Detection Using Smartwatches: A Systematic Review.
Pay L, Yumurtaş AÇ, Satti DI, Hui JMH, Chan JSK, Mahalwar G, Lee YHA, Tezen O, Birdal O, Inan D, Özkan E, Tse G, Çinier G
Anatol J Cardiol 2023 Mar;27(3):126-131. doi: 10.14744/AnatolJCardiol.2023.2799. PMID: 36856589Free PMC Article
Beta-blockers for congestive heart failure in children.
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y
Cochrane Database Syst Rev 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. PMID: 32700759Free PMC Article
Systematic review of cardiac electrical disease in Kearns-Sayre syndrome and mitochondrial cytopathy.
Kabunga P, Lau AK, Phan K, Puranik R, Liang C, Davis RL, Sue CM, Sy RW
Int J Cardiol 2015 Feb 15;181:303-10. Epub 2014 Dec 13 doi: 10.1016/j.ijcard.2014.12.038. PMID: 25540845
Third-degree heart block associated with lyme carditis: review of published cases.
Forrester JD, Mead P
Clin Infect Dis 2014 Oct;59(7):996-1000. Epub 2014 May 30 doi: 10.1093/cid/ciu411. PMID: 24879781

Supplemental Content

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    Related information

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    • GTR(Clinical)
      Clinical tests in GTR
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