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Select item 35911.

Quinine effect on yeast eukaryotic model

Analysis of Saccharomyces cerevisiae cells subjected to anti-malaria drug quinine (QN) at concentration that exerted a very slight effect on cellular growth. Results provide insight into the molecular mechanisms underlying QN action and the host response to the drug.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL90
Series:: GSE18037
4 Samples

Download data: CEL

DataSet

Accession:: GDS3591

ID:: 3591

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 33322.

Wine fermentation effect on yeast: time course

Analysis of Saccharomyces cerevisiae, strain Vin13, subjected to ethanol levels up to 10% during a 15-day wine fermentation. Results provide insight into molecular mechanisms underlying the adaptive response of yeast to the long-term environmental stresses present during alcoholic fermentation.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 6 stress, 7 time sets

Platform:: GPL90
Series:: GSE8536
21 Samples

Download data: CEL

DataSet

Accession:: GDS3332

ID:: 3332

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 32453.

S288C cell response to pterostilbene

Analysis of strain S288C cells subjected to pterostilbene at the IC50 concentration (70uM) for one generation (3h). Pterostilbene, an analog of resveratrol, is a phytoalexin exhibiting potent antifungal activity. Results provide insight into the molecular pathways affected by pterostilbene.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL90
Series:: GSE10554
6 Samples

Download data: CEL

DataSet

Accession:: GDS3245

ID:: 3245

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 31374.

Antifungal compound sampangine effect on Saccharomyces cerevisiea

Analysis of Saccharomyces cerevisiae cells treated with the antifungal compound sampangine. Sampangine exhibits strong inhibitory activity against opportunistic fungal pathogens such as Candida albicans. Using S. cerevisiae as a model, results provide insight into sampangine's mechanism of action.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL90
Series:: GSE10073
6 Samples

Download data: CEL

DataSet

Accession:: GDS3137

ID:: 3137

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 34385.

Budding yeast response to hypoxia

Analysis of Saccharomyces cerevisiae wild type cells grown under reduced oxygen tension. Heme synthesis requires oxygen, and yeast grown anaerobically exhibit an increased uptake of hemin. Results provide insight into the molecular mechanisms regulating heme uptake.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL90
Series:: GSE9514
4 Samples

Download data: CEL

DataSet

Accession:: GDS3438

ID:: 3438

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 34376.

Budding yeast response to heme deficiency

Analysis of Saccharomyces cerevisiae mutant cells lacking aminolevulinic acid (ALA) synthase. ALA synthase catalyzes the first step of heme biosynthesis. Heme uptake is induced by heme starvation in S. cerevisiae. Results provide insight into the molecular mechanisms regulating heme uptake.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL90
Series:: GSE9514
4 Samples

Download data: CEL

DataSet

Accession:: GDS3437

ID:: 3437

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 30617.

Ribosomal protein null mutants

Analysis of several Saccharomyces cerevisiae mutants each deficient in one of various ribosomal proteins. S. cerevisiae contains many duplicated genes encoding ribosomal proteins. Results provide insight into the unique role of each member of a pair of ribosomal protein paralogs.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 12 genotype/variation sets

Platform:: GPL90
Series:: GSE8761
24 Samples

Download data: CEL

DataSet

Accession:: GDS3061

ID:: 3061

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 30818.

not1-2 spt3 double mutant

Analysis of not1-2 spt3 double mutant cells. NOT1 encodes the scaffold subunit of the Ccr4-Not transcription factor complex. SPT3 encodes a transcription factor. The temperature sensitive not1-2 mutant exhibits transcriptional defects that are suppressed by the deletion of SPT3.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 4 genotype/variation sets

Platform:: GPL90
Series:: GSE9432
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3081

ID:: 3081

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 30359.

Saccharomyces cerevisiae response to oxidative stress: time course

Analysis of Saccharomyces cerevisiae cultures at various time points up to 120 minutes following treatment with the oxidant cumene hydroperoxide (CHP). Results provide insight into molecular mechanisms underlying the response of the yeast S. cerevisiae to oxidative stress.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 2 agent, 8 time sets

Platform:: GPL90
Series:: GSE7645
48 Samples

Download data: CEL

DataSet

Accession:: GDS3035

ID:: 3035

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 299910.

Gentamicin effect on Saccharomyces cerevisiae

Analysis of Saccharomyces cerevisiae strain 4073 cultures treated with gentamicin. Gentamicin is an antibiotic used against gram-negative bacterial infections. Its usefulness is limited by nephrotoxicity. Results provide insight into the molecular mechanisms underlying gentamicin's renal toxicity.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL90
Series:: GSE7188
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2999

ID:: 2999

GEO Profiles Analyze DataSet

Select item 296911.

Carbon dioxide effect on fermenting yeast: dose response

Analysis of chemostat cultures sparged with 79% or 100% carbon dioxide (CO2). During fermentation and ethanol production, CO2 is produced, saturating the fermentative broth. Results provide insight into the mechanisms underlying CO2 stress.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 4 dose, 2 growth protocol sets

Platform:: GPL90
Series:: GSE8900
18 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2969

ID:: 2969

Select item 280412.

Quiescent stb3 null mutant response to glucose

Analysis of the response of quiescent stb3 null cells to glucose. STB3 encodes a protein that binds to the Ribosomal RNA Processing Element, a DNA sequence motif that regulates genes needed for growth. Results provide insight into Stb3’s role during the transition from quiescence to rapid growth.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 growth protocol sets

Platform:: GPL90
Series:: GSE8379
8 Samples

Download data: CEL

DataSet

Accession:: GDS2804

ID:: 2804

Select item 266313.

Mre11 deficient sporulating cells

Analysis of Mre11 deficient cells at meiotic prophase during sporulation. Mre11 is important in homologous recombination, repair of DNA double strand breaks, activation of damage-induced checkpoint, and telomere maintenance. Results provide insight into the role of Mre11 in spore development.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 development stage, 4 genotype/variation sets

Platform:: GPL90
Series:: GSE6620
8 Samples

Download data: CEL

DataSet

Accession:: GDS2663

ID:: 2663

Select item 292514.

Various weak organic acids effect on anaerobic yeast chemostat cultures

Analysis of anaerobic chemostat cultures of Saccharomyces cerevisae exposed to one of several weak organic acids. Weak organic acids are used as preservatives in food and beverages. Yeasts are able to proliferate at the maximum legal dosage of such preservatives.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 5 stress sets

Platform:: GPL90
Series:: GSE5926
15 Samples

Download data: CEL

DataSet

Accession:: GDS2925

ID:: 2925

Select item 252215.

Pyocyanin treatment: dose response

Analysis of cells treated with 25 or 250 ug/ml of the blue metabolite pyocyanin for 6 hours. Pyocyanin, produced by Pseudomonas aeruginosa, kills cells by generating reactive oxygen species. Results provide insight into the molecular mechanisms underlying the stress response to pyocyanin.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 agent, 3 dose sets

Platform:: GPL90
Series:: GSE6185
6 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2522

ID:: 2522

Select item 262516.

mRNA decapping activator edc3 null mutant

Analysis of edc3 null mutant cells. EDC3 encodes an mRNA decapping activator. Results provide insight into the role of Edc3p in mRNA decay.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL90
Series:: GSE6647
10 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2625

ID:: 2625

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 319817.

Abf1 DNA-binding mutant

Analysis of temperature sensitive Abf1 mutant cells subjected to a temperature of 37 degrees C to dissociate the mutant protein from its DNA binding sites. Results provide insight into the contribution of this general regulatory factor to transcription genome-wide.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL90
Series:: GSE6073
6 Samples

Download data: CEL

DataSet

Accession:: GDS3198

ID:: 3198

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 253318.

Rap1 DNA-binding mutant

Analysis of temperature sensitive Rap1 mutant cells subjected to a temperature of 37 degrees C to dissociate the mutant protein from its DNA binding sites. Results provide insight into the contribution of this general regulatory factor to transcription genome-wide.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL90
Series:: GSE6073
6 Samples

Download data: CEL

DataSet

Accession:: GDS2533

ID:: 2533

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 250819.

DNA damage effect

Analysis of cells exposed to the radiomimetic enediyne antibiotics calicheamicin, esperamicin A1, and neocarzinostatin. These enediynes bind specifically to DNA and generate single- and double-strand DNA breaks. Results provide insight into the response to DNA damage.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, count, 6 agent sets

Platform:: GPL90
Series:: GSE5301
18 Samples

Download data

DataSet

Accession:: GDS2508

ID:: 2508

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 161120.

Nonsense-mediated mRNA decay factor upf1 null mutant response to global transcription inhibition: time course

Analysis of wild type and mutant upf1 strains up to 60 minutes after treatment with 10 ug/ml thiolutin, a global transcription inhibitor. Upf1 is an RNA helicase required for nonsense-mediated mRNA decay (NMD). Results identify genes with differential expression over time between the two strains.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 16 time sets

Platform:: GPL90
Series:: GSE3076
96 Samples

Download data: CEL, CHP, EXP

DataSet

Accession:: GDS1611

ID:: 1611

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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