GEO DataSets

(Submitter supplied) The aryl hydrocarbon receptor repressor (AHRR) is a bHLH-PAS protein closely related to the aryl hydrocarbon receptor (AHR). AHRR is a transcriptional repressor of AHR and hypoxia-inducible factor (HIF) and is regulated by an AHR-dependent mechanism. Zebrafish possess two AHRR paralogs; AHRRa regulates constitutive AHR signaling during development, while AHRRb regulates polyaromatic hydrocarbon-induced gene expression. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

6 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Danio rerio

Type:

Expression profiling by array

Platforms:

GPL7302 GPL14664

83 Samples

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(Submitter supplied) Overexpression experiments with or without protein synthesis inhibition were performed to investigate transcriptional targets of Klf4, FoxD3, and Nanog-like in the blastula stage embryos (4.7 hours postfertilization) of wild type or MZspg background.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

30 Samples

Download data: TXT

(Submitter supplied) Pou5f1 and Sox2 overexpression experiments with protein synthesis inhibitor were performed to investigate direct transcriptional targets of Pou5f1 and Sox2

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

16 Samples

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(Submitter supplied) Background: Development and application of transcriptomics-based gene classifiers for ecotoxicological applications lag far behind those of human biomedical science. Many such classifiers discovered thus far lack vigorous statistical and experimental validations, with their stability and reliability unknown. A combination of genetic algorithm/support vector machines and genetic algorithm/K nearest neighbors were used in this study to search for classifiers of endocrine disrupting chemicals (EDCs) in zebrafish. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platforms:

GPL7301 GPL7244 GPL7302

318 Samples

Download data: TXT

(Submitter supplied) The study was aimed at comparing the transcriptome of MG cells of the retina with the progenitors derived from them after an injury. This information will help in the identification of factors that are responsible for the retinal regeneration.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

4 Samples

Download data: TXT

(Submitter supplied) Transcripts for GH, MHC Class I and II genes, and heavy- and light-chain myosins, as well as many others genes, were differentially regulated in the zebrafish inner ear following overexposure to sound.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

9 Samples

Download data: TXT

(Submitter supplied) In mature human sperm, genes of importance for embryo development (i.e. transcription factors) lack DNA methylation and bear nucleosomes with distinctive histone modifications, suggesting the specialized packaging of these developmental genes in the germline. Here, we explored the tractable zebrafish model and found conceptual conservation as well as several new features. Biochemical and mass spectrometric approaches reveal the zebrafish sperm genome packaged in nucleosomes and histone variants (and not protamine), and we find linker histones high and H4K16ac absent - key factors which may contribute to genome condensation. more...

Organism:

Danio rerio

Type:

Genome binding/occupancy profiling by genome tiling array; Methylation profiling by genome tiling array; Expression profiling by array

Platforms:

GPL6600 GPL7302 GPL6601

38 Samples

Download data: TXT

(Submitter supplied) Adult zebrafish have the ability to recover from spinal cord injury and exhibit re-growth of descending axons from the brainstem to the spinal cord. We performed gene expression analysis using microarray to find damage-induced genes after spinal cord injury, which shows that Sox11b mRNA is up-regulated at 11 days after injury. However, the functional relevance of Sox11b for regeneration is not known. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

18 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Danio rerio

Type:

Expression profiling by array

Platforms:

GPL1319 GPL7302

96 Samples

Download data: CEL, TXT

(Submitter supplied) Pou5f1 and Sox2 overexpression experiments with and without protein synthesis inhibitor were performed to investigate direct transcriptional targets of Pou5f1 and Sox2

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

18 Samples

Download data: TXT

(Submitter supplied) Comparison of Mspg and MZspg mutants at two stages, zebrafish

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

12 Samples

Download data: TXT

(Submitter supplied) Developmental curve of zebrafish MZ spg mutants compared to WT, 10 timepoints from 0 to 8 hours post fertilization transcriptome changes by microarray analysis at ten distinct time-points during development, from ovaries to late gastrulation, in MZ spg and WT zebrafish

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

58 Samples

Download data: TXT

(Submitter supplied) To comprehensively understand the genes affected by beta-arrestin1 depletion in zebrafish fish embryos at 12 hpf, microarray analysis was performed. As controls, zebrafish embryos depleted of beta-arrestin2 and double depletion of beta-arrestin1 and beta-arrestin2 were also analyzed.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

4 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of 24 hours post-fertilization zebrafish embryos comparing control untreated embryos with embryos raised in 75uM 5-azadC. 5-azadC blocks methylation. The goal was to determine genes regulated by methylation during development.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7302

3 Samples

Download data: TXT

(Submitter supplied) Design ID: 015064 Agilent has developed a genome-wide zebrafish microarray to enable scientists to study gene expression profiling at the global level and enhance our understanding of zebrafish biology and gene functions related to mammalian models. *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL6563. more...

Organism:

Danio rerio

15 Series

1 Related Platform

411 Samples

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(Submitter supplied) Design ID: 015064 Agilent has developed a genome-wide zebrafish microarray to enable scientists to study gene expression profiling at the global level and enhance our understanding of zebrafish biology and gene functions related to mammalian models. Arrays of this design have barcodes that begin with 16015064 or 2515064. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...

Organism:

Danio rerio

8 Series

1 Related Platform

136 Samples

Download data: TXT