GSE56143[Accession] - GEO DataSets - NCBI

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Items: 15

Select item 2000561431.

Identification of mechano- and/or 5Aza-sensitive genes in mouse carotid artery endothelium in vivo exposed to disturbed blood flow for 7 days

(Submitter supplied) Atherosclerosis preferentially occurs in arterial regions of disturbed blood flow (d-flow), which alters gene expression, endothelial function, and atherosclerosis. Here, we show that d-flow regulates genome-wide DNA methylation patterns in a DNA methyltransferase (DNMT)-dependent manner. D-flow induced expression of DNMT1 in mouse arterial endothelium in vivo and in cultured endothelial cells by oscillatory shear (OS) in vitro. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5651
Platform:: GPL6887
12 Samples

Download data: TXT

Series

Accession:: GSE56143

ID:: 200056143

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 56512.

Full record GDS5651

DNA methyltransferase inhibitor 5-Aza-2’deoxycytidine effect on partially-ligated left carotid artery

Analysis of arteries from C57BL/6 males pretreated with DNMT inhibitor 5Aza for 2 wk, then subjected to partial carotid ligation (PCL) and continued 5Aza treatment for 1 wk after ligation. PCL induces disturbed blood flow. Results provide insight into molecular basis of atherosclerosis development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 protocol, 2 tissue sets

Platform:: GPL6887
Series:: GSE56143
12 Samples

DataSet

Accession:: GDS5651

ID:: 5651

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000068873.

Illumina MouseWG-6 v2.0 expression beadchip

(Submitter supplied) The MouseWG-6 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...

Organism:: Mus musculus

31 DataSets
1220 Series
8 Related Platforms
17144 Samples

Download data: BGX, TXT

Platform

Accession:: GPL6887

ID:: 100006887

Select item 3013566514.

Organism:: Mus musculus

Source name:: right carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356651

ID:: 301356651

Select item 3013566505.

Organism:: Mus musculus

Source name:: right carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356650

ID:: 301356650

Select item 3013566496.

Organism:: Mus musculus

Source name:: right carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356649

ID:: 301356649

Select item 3013566487.

Organism:: Mus musculus

Source name:: left carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356648

ID:: 301356648

Select item 3013566478.

Organism:: Mus musculus

Source name:: left carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356647

ID:: 301356647

Select item 3013566469.

Organism:: Mus musculus

Source name:: left carotid artery, 21 days of 5-Aza-2'deoxycytidine treatment (0.2mg/kg/day by I.P. injection), 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356646

ID:: 301356646

Select item 30135664510.

Organism:: Mus musculus

Source name:: right carotid artery, saline-treated control, unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356645

ID:: 301356645

Select item 30135664411.

Organism:: Mus musculus

Source name:: right carotid artery, saline-treated control, unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356644

ID:: 301356644

Select item 30135664312.

Organism:: Mus musculus

Source name:: right carotid artery, saline-treated control, unligated contralateral control

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356643

ID:: 301356643

Select item 30135664213.

Organism:: Mus musculus

Source name:: left carotid artery, saline-treated control, 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356642

ID:: 301356642

Select item 30135664114.

Organism:: Mus musculus

Source name:: left carotid artery, saline-treated control, 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356641

ID:: 301356641

Select item 30135664015.

Organism:: Mus musculus

Source name:: left carotid artery, saline-treated control, 7 days ligated

Platform:: GPL6887
Series:: GSE56143
Dataset:: GDS5651

Sample

Accession:: GSM1356640

ID:: 301356640

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