Similar studies for GEO DataSets (Select 200093171) - GEO DataSets

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Items: 20

Select item 2000931711.

microRNA profile in CD4+ T cell in healthy control and Primay biliary cholangitis (PBC) [miRNA]

(Submitter supplied) Primary biliary cholangitis (PBC), formally known as primary biliary cirrhosis, is an autoimmune liver disease of unknown pathogenesis. Consequently, therapeutic targets for PBC have yet to be identified. As CD4+ T cells play a pivotal role in immunological dysfunction observed in PBC, we analyzed microRNA(miRNA) and mRNA expression in CD4+ T cells to investigate PBC pathogenesis and identify novel therapeutic targets.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL16770
12 Samples

Download data: TXT

Series

Accession:: GSE93171

ID:: 200093171

Select item 2000931702.

mRNA profile in CD4+ T cell in healthy control and Primay biliary cholangitis (PBC) [mRNA]

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL14550
12 Samples

Download data: TXT

Series

Accession:: GSE93170

ID:: 200093170

Select item 2000489593.

Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6244
48 Samples

Download data: CEL

Series

Accession:: GSE48959

ID:: 200048959

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000489584.

Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

(Submitter supplied) In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
21 Samples

Download data: CEL

Series

Accession:: GSE48958

ID:: 200048958

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000489575.

Mucosal miRNA expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
27 Samples

Download data: CEL

Series

Accession:: GSE48957

ID:: 200048957

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000791906.

The transcriptional profile analysis of mice peritoneal cavity B1a cells from p40-/-CD25-/- mice

(Submitter supplied) We have found many differences between B1a cells from p40-/-CD25-/- mice and control mice. To better understand the whole change of transcriptions profile between B1a cells in PC of p40-/-CD25-/- mice and control mice. By using flow cytometry and high-resolution microarrays, we have studied qualitative and quantitative characteristics of B1a cells of p40-/-CD25-/- mice and control mice.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
6 Samples

Download data: TXT

Series

Accession:: GSE79190

ID:: 200079190

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000582207.

Expression data from primary term human decidual cells treated with interleukin-1-beta for 6 hours.

(Submitter supplied) Preterm birth is an important unsolved clinical problem. Despite advanced treatments, infants who survive prematurity remain at increased risk for permanent disabilities. In approximately one-third of cases, prematurity is related to infection and/or inflammation, which renders hostile the normally receptive intrauterine environment. Proinflammatory cytokines provoke up-regulation of genes that promote uterine contractions. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE58220

ID:: 200058220

Select item 2001043638.

microRNA-21 deletion impairs regulatory T cell function

(Submitter supplied) Background: It has been found that miR-21 is increased in colonic tissues and decreased in peripheral blood regulatory T cells (Tregs) of patients with ulcerative colitis (UC). We aimed to investigate the influence of miR-21 on Tregs function in intestinal inflammation. Methods: Various CD4+ T cell populations were flow-cytometry sorted from miR-21-/- mice and littermates (WT) utilization in T-cell transfer colitis model and suppression of T cell activation and proliferation by Tregs. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
8 Samples

Download data: TXT

Series

Accession:: GSE104363

ID:: 200104363

Select item 2000596519.

Divergent influence of microRNA-21 deletion on murine colitis phenotypes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus; Murid betaherpesvirus 1; JC polyomavirus; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus macacae

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL6885 GPL7723
26 Samples

Download data

Series

Accession:: GSE59651

ID:: 200059651

Select item 20005965010.

Divergent influence of microRNA-21 deletion on murine colitis phenotypes [TNBS]

(Submitter supplied) Background: MicroRNAs (miRNAs) acting as negative regulators of gene expression are differentially expressed in intestinal tissues of patients with inflammatory bowel disease (IBD). Assessing the functional role of miRNAs in murine models of colitis facilitates elucidating the role of specific miRNAs in human IBD. The aim of this study was to determine the miRNA signature of murine models of colitis and to assess the influence of miR-21 on intestinal inflammation. more...

Organism:: Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Rattus norvegicus; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae

Type:: Non-coding RNA profiling by array

Platform:: GPL7723
8 Samples

Download data: TXT

Series

Accession:: GSE59650

ID:: 200059650

Select item 20005964911.

Divergent influence of microRNA-21 deletion on murine colitis phenotypes [DSS]

Organism:: Rattus norvegicus; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae

Type:: Non-coding RNA profiling by array

Platform:: GPL7723
12 Samples

Download data: TXT

Series

Accession:: GSE59649

ID:: 200059649

Select item 20005964812.

Divergent influence of microRNA-21 deletion on murine colitis phenotypes [mRNA]

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
6 Samples

Download data: TXT

Series

Accession:: GSE59648

ID:: 200059648

Select item 20008421813.

Tthe transcriptional profile analysis of mice liver CD8+ T cells from dnTGFβRII (TG) mice VS.dnTGFβRII CXCR3-/- (TGC3) mice

(Submitter supplied) Based on the data we obtained we next focused on potential intrinsic changes of CD8+ T cells. Gene expression proﬁles of CD8+ T cells isolated from livers of both the TG and TGC3 mice were analyzed by gene microarray.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
6 Samples

Download data: TXT

Series

Accession:: GSE84218

ID:: 200084218

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005501314.

Profiling of in vitro differentiated activated T helper cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Mus musculus

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL16570 GPL16384
20 Samples

Download data: CEL, XLSX

Series

Accession:: GSE55013

ID:: 200055013

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005501215.

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation

(Submitter supplied) Combined analysis of mRNA and miRNA transcriptoms revealed a complex network regulating major immune regulatory signaling pathways

Organism:: synthetic construct; Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL16384
10 Samples

Download data: CEL

Series

Accession:: GSE55012

ID:: 200055012

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005501116.

Profiling of in vitro differentiated activated T helper cells [mRNA]

(Submitter supplied) Combined analysis of mRNA and miRNA transcriptoms revealed a complex network regulating major immune regulatory signaling pathways

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL16570
10 Samples

Download data: CEL

Series

Accession:: GSE55011

ID:: 200055011

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20009894017.

MiR-204-3p inhibits the production of TLR4-related cytokines in familial Mediterranean fever by targeting the PI3Kγ signaling pathway

(Submitter supplied) Our data suggest that serum miR-204-3p has a potential as a useful biomarker among patients with FMF and that miR-204-3p plays a critical role as a suppressor to regulate the production of TLR4-related cytokines by targeting PI3K signaling pathway.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL20844
4 Samples

Download data: TXT

Series

Accession:: GSE98940

ID:: 200098940

Select item 20003721318.

MiR-21 function in T-lymphocytes

(Submitter supplied) T-lymphocyte activation is efficiently mimicked in vitro by treatment with anti CD3 / anti CD28 antibodies. We report miR-21 induction upon CD3/CD28 stimulation of primary T-lymphocytes. In order to assess the function of miR-21 in T-lymphocytes we interfered with miR-21 function by lentiviral transduction of a miR-21 sponge construct. MRNA profile of miR-21 sponge and control transduced T-lymphocytes 48hrs after stimulation.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
6 Samples

Download data: CEL

Series

Accession:: GSE37213

ID:: 200037213

Select item 20003721219.

Identification of miR-21 targets in Jurkat cells by AGO2 immunoprecipitation

(Submitter supplied) In order to identify miR-21 targets by a biochemical high-throughput method, we immunopurified RISC Complex and associated mRNAs in both control and miR-21 overexpressing Jurkat cells.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
12 Samples

Download data: CEL

Series

Accession:: GSE37212

ID:: 200037212

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001645320.

Characterization of microRNA Expression Profiles in human primary differentiated T lymphocytes

(Submitter supplied) Activation of the T cell-mediated immune response has been associated with changes in the expression of specific miRNAs. However, the role of miRNAs in the development of an effective immune response is just beginning to be explored. Here we report a microRNA expression profile showing a list of microRNAs, which are highly up-regulated or down-regulated in human memory T cells compared to naive T cells, thus suggesting a possible role of these microRNAs in T lymphocyte differentiation. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8664
4 Samples

Download data: XLS

Series

Accession:: GSE16453

ID:: 200016453

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