Similar studies for GEO DataSets (Select 200123122) - GEO DataSets

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Items: 20

Select item 2001231221.

Transcript levels of genes in both the wild type SN148 and the crz1/crz1 mutant with or without 0.2M CaCl2 treatment

(Submitter supplied) We report the expression levels of transcripts for two alleles of 6,211 genes in log-phase growing cells of the wild type SN148 and the crz1/crz1 with or without 0.2M CaCl2 treatment.We find that as compared to the wild type cells without 0.2M CaCl2 treatment, there are 828 genes upregulated in the wild type cells with 0.2M CaCl2 treatment.

Organism:: Candida albicans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23041
4 Samples

Download data: XLSX

Series

Accession:: GSE123122

ID:: 200123122

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001007372.

Transcript levels of genes in the wild type CAI4 as well as the gdt1/gdt1,the pmr1/pmr1 and the gdt1/gdt1 pmr1/pmr1 mutants

(Submitter supplied) We report the expression levels of transcripts of 5,901 genes in log-phase growing cells of the wild type CAI4 as well as the gdt1/gdt1, the pmr1/pmr1, and the gdt1/gdt1 pmr1/pmr1 mutants.We find that as compared to the wild type, there are 249, 446 and 440 differentially expressed genes (DEGs) in the gdt1/gdt1, the pmr1/pmr1 and the gdt1/gdt1 pmr1/pmr1 mutants, respectively. Deletion of CaGDT1 does not affect the transcript level of CaPMR1, and vice versa. more...

Organism:: Candida albicans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19036
4 Samples

Download data: XLS

Series

Accession:: GSE100737

ID:: 200100737

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000930053.

Extensive rewiring of the Calcineurin-Crz1 stress response network in the human fungal pathogen Cryptococcus neoformans

(Submitter supplied) Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus neoformans, calcineurin is activated by multiple stresses including high temperature, and is essential for stress adaptation and virulence. The transcription factor Crz1 is a major calcineurin effector in Saccharomyces cerevisiae and other fungi. more...

Organism:: Cryptococcus neoformans var. grubii H99

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21548
28 Samples

Download data: TAB

Series

Accession:: GSE93005

ID:: 200093005

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000719044.

Function and regulation of Cph2 in Candida albicans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Candida albicans

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL19036
10 Samples

Download data

Series

Accession:: GSE71904

ID:: 200071904

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Select item 2000719025.

Function and regulation of Cph2 in Candida albicans [RNA-Seq]

(Submitter supplied) Candida albicans is associated with humans as both a harmless commensal organism and a pathogen. Cph2 is a transcription factor whose DNA binding domain is similar to mammalian sterol response element binding proteins (SREBPs). SREBPs are master regulators of cellular cholesterol levels, and are highly conserved from fungi to mammals. However, ergosterol biosynthesis is regulated by the zinc finger transcription factor Upc2 in C. more...

Organism:: Candida albicans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19036
4 Samples

Download data: TXT

Series

Accession:: GSE71902

ID:: 200071902

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000717286.

Function and regulation of Cph2 in Candida albicans [ChIP-Seq]

Organism:: Candida albicans

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL19036
6 Samples

Download data: TXT

Series

Accession:: GSE71728

ID:: 200071728

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000793427.

Genome-wide recruitment profiling of transcription factor Crz1 in response to high pH stress

(Submitter supplied) Exposure of the budding Saccharomyces cerevisiae to an alkaline environment produces a robust transcriptional response involving hundreds of genes. Part of this response is triggered by an almost immediate burst of calcium that activates the Ser/Thr protein phosphatase calcineurin. Activated calcineurin dephosphorylates the transcription factor Crz1, which moves to the nucleus and binds to calcineurin/Crz1 responsive gene promoters. more...

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17143
10 Samples

Download data: TXT

Series

Accession:: GSE79342

ID:: 200079342

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000510648.

Transcriptional profiling of Candida albicans cells defective in glucan assembly and undergoing the Yeast to Hyphal transition

(Submitter supplied) Wild type (CAI10) and phr1 null mutant (CAS10) were analyzed at 0, 1, 3 and 5 hours after the shift of blastospores to Hyphae inducing conditions

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL9545
24 Samples

Download data: TXT

Series

Accession:: GSE51064

ID:: 200051064

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000777619.

Conserved and diverged functions of the calcineurin-activated Prz1 transcription factor in fission yeast

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL16235 GPL16187
18 Samples

Download data: GPR

Series

Accession:: GSE77761

ID:: 200077761

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007776010.

Genome-wide analysis of Prz1 in fission yeast reveals a novel inhibitory role in flocculation and a conserved activating role in cell wall organization [ChIP-chip]

(Submitter supplied) Gene regulation in response to intracellular calcium is mediated by the calcineurin-activated transcription factor Prz1 in the fission yeast Schizosaccharomyces pombe. Genome-wide studies of the Crz1 and CrzA fungal orthologs have uncovered numerous target genes involved in conserved and species-specific cellular processes. In contrast, very few target genes of Prz1 have been published. This paper identified an extensive list of genes using transcriptome and ChIP-chip analyses under inducing conditions of Prz1, including CaCl2, and tunicamycin treatment, as well as a ∆pmr1 genetic background. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL16235
4 Samples

Download data: GPR

Series

Accession:: GSE77760

ID:: 200077760

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007775911.

Genome-wide analysis of Prz1 in fission yeast reveals a novel inhibitory role in flocculation and a conserved activating role in cell wall organization [expression]

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by array

Platform:: GPL16187
14 Samples

Download data: GPR

Series

Accession:: GSE77759

ID:: 200077759

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000872712.

Genome-wide expression and location analyses of the Candida albicans Tac1p regulon

(Submitter supplied) A major mechanism of azole resistance in Candida albicans is the over-expression of the genes encoding the ABC transporters Cdr1p and Cdr2p. Constitutive over-expression of these efflux pumps is due to mutations in the gene encoding Tac1p, resulting in hyperactivity of this zinc cluster transcription factor. In order to identify the transcriptional targets of Tac1p, we examined four matched sets of clinical isolates representing the development of CDR1- and CDR2-mediated azole resistance, using gene expression profiling analysis. more...

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL5723
27 Samples

Download data: CEL, CHP

Series

Accession:: GSE8727

ID:: 200008727

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Select item 20004126613.

Comparative analysis between wild type and hap5-null mutant in response to rapamycin treatment

(Submitter supplied) To identify the potential Hap5-regulated genes, we treated wild type cells and hap5 mutant cells with rapamycin and their corespondent transcriptional profiles were compared. Total 608 significant genes were identified. Among them, 343 genes are upregulated in hap5 mutant in repsonse to rapamycin while 265 genes are downregulated in comparison with the wild type.

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL14575
8 Samples

Download data: TXT

Series

Accession:: GSE41266

ID:: 200041266

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002517414.

The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion

(Submitter supplied) Biofilm development by Candida albicans requires cell adhesion for the initial establishment of the biofilm and the continued stability after hyphal development occurs; however, the regulation of the process has not been fully established. Using chromatin immunoprecipitation coupled to microarray analysis (ChIP-chip) we have characterized a regulon containing the Mcm1p factor that is required for the initial surface adhesion during biofilm formation. more...

Organism:: Candida albicans

Type:: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL10637 GPL9818
7 Samples

Download data: TXT

Series

Accession:: GSE25174

ID:: 200025174

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Select item 20013365715.

Transcription profiling of the wild-type strain, mhy1Δ mutant and MHY1-overexpressing mutant strain.

(Submitter supplied) To explore the cellular functions of Mhy1, how Mhy1 promotes filamentation, we wanted to identify genes that are transcriptionally controlled by Mhy1. To this end, RNA-Seq analysis was conducted in cells of wild-type strain, mhy1Δ mutant and wild-type strain overexpressing MHY1 grown in filament-inducing YNDC7 medium.

Organism:: Yarrowia lipolytica

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21780
3 Samples

Download data: TXT

Series

Accession:: GSE133657

ID:: 200133657

PubMed Similar studies SRA Run Selector

Select item 20012344616.

AtrR is an essential determinant of azole resistance in Aspergillus fumigatus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Aspergillus fumigatus Af293

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL25869 GPL25907
14 Samples

Download data: TXT, WIG

Series

Accession:: GSE123446

ID:: 200123446

PubMed Full text in PMC Similar studies

Select item 20012344517.

RNA-seq analysis of alleles of the atrR transcription factor-encoding gene in Aspergillus fumigatus

(Submitter supplied) Determine the transcriptomic response of Aspergillus fumigatus strains to different alleles of atrR

Organism:: Aspergillus fumigatus Af293

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25907
8 Samples

Download data: TXT, WIG

Series

Accession:: GSE123445

ID:: 200123445

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20012315918.

ChIP-seq analysis of transcription factor AtrR binding across the Aspergillus fumigatus genome

(Submitter supplied) To determine the genomic binding sites for the Aspergillus fumigatus transcription factor AtrR, we utilized three different strains. One was the wild-type AfS35 which contains a wild-type copy of atrR but lacks any HA tag. The other two are both derived from AfS35 but contain a 3X HA tag replacing the stop codon of atrR. These strains are SPF89 and SPF112, respectively. SPF89 uses the wild-type atrR promoter to drive expression of the epitope-tagged allele while SPF112 uses the much strong hspA promoter to drive production of the same protein.

Organism:: Aspergillus fumigatus Af293

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25869
6 Samples

Download data: WIG

Series

Accession:: GSE123159

ID:: 200123159

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20005307319.

RNA Seq in wild type and zfs1 deficient C. albicans

(Submitter supplied) Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins bind to AU-rich regions in the 3'-untranslated regions (UTR) of target mRNAs, leading to their deadenylation and accelerated decay. Family members in S. cerevisiae influence iron metabolism, whereas the family member in S. pombe leads to defects in cell-cell interactions. In the important human fungal pathogen Candida albicans, deep sequencing of transcripts in mutants deficient in the analogous protein, Zfs1p, revealed 156 transcripts whose levels were significantly increased by at least 1.5-fold. more...

Organism:: Candida albicans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15149
11 Samples

Download data: TXT

Series

Accession:: GSE53073

ID:: 200053073

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20001510420.

Identification of the Candida albicans Cap1p regulon (Cap1-CSE-HA and Cap1-HA complete datasets)

(Submitter supplied) Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Cap1p in C. albicans, we used genome-wide location profiling (ChIP-on-chip) to identify its transcriptional targets in vivo. more...

Organism:: Candida albicans

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL4037
6 Samples

Download data: PAIR

Series

Accession:: GSE15104

ID:: 200015104

PubMed Full text in PMC Similar studies Analyze with GEO2R

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