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Recurrent Childhood Malignant Neoplasm

MedGen UID:
1703882
•Concept ID:
C5206756
•
Neoplastic Process

Definition

The reemergence of a childhood malignant neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Malignant Neoplasm

Professional guidelines

PubMed

Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management.
Kothari R, Szepietowski JC, Bagot M, Sandhu S, Patil A, Grabbe S, Goldust M
Int J Dermatol 2022 Dec;61(12):1458-1466. Epub 2022 Feb 22 doi: 10.1111/ijd.16098. PMID: 35193164
Diagnostic and Management Considerations in Pediatric Dermatofibrosarcoma Protuberans.
Reilly DJ, Loo YL, Alexander WM, Wilks DJ, MacGregor D, Coombs CJ
Ann Plast Surg 2022 Mar 1;88(3):319-322. doi: 10.1097/SAP.0000000000002970. PMID: 34387577
Safety of GH after treatment for childhood cancer.
van Santen HM
Eur J Endocrinol 2020 Dec;183(6):C15-C18. doi: 10.1530/EJE-20-0965. PMID: 33136064

Recent clinical studies

Etiology

Anti-GD2 Directed Immunotherapy for High-Risk and Metastatic Neuroblastoma.
Chan GC, Chan CM
Biomolecules 2022 Feb 24;12(3) doi: 10.3390/biom12030358. PMID: 35327550Free PMC Article
Next-Generation Sequencing of Minimal Residual Disease for Predicting Relapse after Tisagenlecleucel in Children and Young Adults with Acute Lymphoblastic Leukemia.
Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Childhood Medulloblastoma: An Overview.
Suk Y, Gwynne WD, Burns I, Venugopal C, Singh SK
Methods Mol Biol 2022;2423:1-12. doi: 10.1007/978-1-0716-1952-0_1. PMID: 34978683
Optimizing medication adherence in children with cancer.
Gupta S, Bhatia S
Curr Opin Pediatr 2017 Feb;29(1):41-45. doi: 10.1097/MOP.0000000000000434. PMID: 27798425Free PMC Article
Wilms tumor.
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Diagnosis

Next-Generation Sequencing of Minimal Residual Disease for Predicting Relapse after Tisagenlecleucel in Children and Young Adults with Acute Lymphoblastic Leukemia.
Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Childhood Medulloblastoma: An Overview.
Suk Y, Gwynne WD, Burns I, Venugopal C, Singh SK
Methods Mol Biol 2022;2423:1-12. doi: 10.1007/978-1-0716-1952-0_1. PMID: 34978683
How I treat relapsed acute lymphoblastic leukemia in the pediatric population.
Hunger SP, Raetz EA
Blood 2020 Oct 15;136(16):1803-1812. doi: 10.1182/blood.2019004043. PMID: 32589723
Wilms tumor.
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525
Acute lymphoblastic leukemia.
Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074

Therapy

Anti-GD2 Directed Immunotherapy for High-Risk and Metastatic Neuroblastoma.
Chan GC, Chan CM
Biomolecules 2022 Feb 24;12(3) doi: 10.3390/biom12030358. PMID: 35327550Free PMC Article
How I treat relapsed acute lymphoblastic leukemia in the pediatric population.
Hunger SP, Raetz EA
Blood 2020 Oct 15;136(16):1803-1812. doi: 10.1182/blood.2019004043. PMID: 32589723
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma.
Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC
Clin Cancer Res 2015 Sep 15;21(18):4062-72. Epub 2015 Jun 9 doi: 10.1158/1078-0432.CCR-15-0428. PMID: 26059190Free PMC Article
Craniopharyngioma.
Müller HL
Handb Clin Neurol 2014;124:235-53. doi: 10.1016/B978-0-444-59602-4.00016-2. PMID: 25248591
Acute lymphoblastic leukemia.
Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074

Prognosis

How I treat relapsed acute lymphoblastic leukemia in the pediatric population.
Hunger SP, Raetz EA
Blood 2020 Oct 15;136(16):1803-1812. doi: 10.1182/blood.2019004043. PMID: 32589723
Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16.
Jeha S, Pei D, Choi J, Cheng C, Sandlund JT, Coustan-Smith E, Campana D, Inaba H, Rubnitz JE, Ribeiro RC, Gruber TA, Raimondi SC, Khan RB, Yang JJ, Mullighan CG, Downing JR, Evans WE, Relling MV, Pui CH
J Clin Oncol 2019 Dec 10;37(35):3377-3391. Epub 2019 Oct 28 doi: 10.1200/JCO.19.01692. PMID: 31657981Free PMC Article
Childhood cutaneous leiomyosarcoma.
Blaise G, Nikkels AF, Quatresooz P, Hermanns-Lê T, Piérard GE
Pediatr Dermatol 2009 Jul-Aug;26(4):477-9. doi: 10.1111/j.1525-1470.2009.00961.x. PMID: 19689533
Acute lymphoblastic leukemia.
Chan KW
Curr Probl Pediatr Adolesc Health Care 2002 Feb;32(2):40-9. doi: 10.1067/mps.2002.121790. PMID: 11951089
Wilms tumor.
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Clinical prediction guides

Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia.
Lorentzian AC, Rever J, Ergin EK, Guo M, Akella NM, Rolf N, James Lim C, Reid GSD, Maxwell CA, Lange PF
Nat Commun 2023 Nov 21;14(1):7161. doi: 10.1038/s41467-023-42701-9. PMID: 37989729Free PMC Article
Next-Generation Sequencing of Minimal Residual Disease for Predicting Relapse after Tisagenlecleucel in Children and Young Adults with Acute Lymphoblastic Leukemia.
Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Bortezomib reinduction chemotherapy in high-risk ALL in first relapse: a report from the Children's Oncology Group.
Horton TM, Whitlock JA, Lu X, O'Brien MM, Borowitz MJ, Devidas M, Raetz EA, Brown PA, Carroll WL, Hunger SP
Br J Haematol 2019 Jul;186(2):274-285. Epub 2019 Apr 7 doi: 10.1111/bjh.15919. PMID: 30957229Free PMC Article
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma.
Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC
Clin Cancer Res 2015 Sep 15;21(18):4062-72. Epub 2015 Jun 9 doi: 10.1158/1078-0432.CCR-15-0428. PMID: 26059190Free PMC Article
Acute lymphoblastic leukemia.
Chan KW
Curr Probl Pediatr Adolesc Health Care 2002 Feb;32(2):40-9. doi: 10.1067/mps.2002.121790. PMID: 11951089

Recent systematic reviews

Safety of intravitreal chemotherapy in the management of retinoblastoma: A systematic review of the literature.
Lavasidis G, Strongylis M, Tzamalis A, Tsinopoulos I, Ntzani EE
Crit Rev Oncol Hematol 2024 Aug;200:104423. Epub 2024 Jun 17 doi: 10.1016/j.critrevonc.2024.104423. PMID: 38897313
Systematic Review and Meta-analysis of CD19-Specific CAR-T Cell Therapy in Relapsed/Refractory Acute Lymphoblastic Leukemia in the Pediatric and Young Adult Population: Safety and Efficacy Outcomes.
Aamir S, Anwar MY, Khalid F, Khan SI, Ali MA, Khattak ZE
Clin Lymphoma Myeloma Leuk 2021 Apr;21(4):e334-e347. Epub 2020 Dec 17 doi: 10.1016/j.clml.2020.12.010. PMID: 33573914
Focal laser treatment in addition to chemotherapy for retinoblastoma.
Fabian ID, Johnson KP, Stacey AW, Sagoo MS, Reddy MA
Cochrane Database Syst Rev 2017 Jun 7;6(6):CD012366. doi: 10.1002/14651858.CD012366.pub2. PMID: 28589646Free PMC Article
Clinical presentation of childhood leukaemia: a systematic review and meta-analysis.
Clarke RT, Van den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ
Arch Dis Child 2016 Oct;101(10):894-901. doi: 10.1136/archdischild-2016-311251. PMID: 27647842
Neuro-ophthalmologic manifestations of systemic lupus erythematosus: a systematic review.
Man BL, Mok CC, Fu YP
Int J Rheum Dis 2014 Jun;17(5):494-501. Epub 2014 Mar 28 doi: 10.1111/1756-185X.12337. PMID: 24673755

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