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Cancer Progression

MedGen UID:
364930
Concept ID:
C1947901
Pathologic Function
Synonym: Cancer Disease Progression

Definition

A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a malignant neoplasm. [from NCI]

Professional guidelines

PubMed

Quail DF, Amulic B, Aziz M, Barnes BJ, Eruslanov E, Fridlender ZG, Goodridge HS, Granot Z, Hidalgo A, Huttenlocher A, Kaplan MJ, Malanchi I, Merghoub T, Meylan E, Mittal V, Pittet MJ, Rubio-Ponce A, Udalova IA, van den Berg TK, Wagner DD, Wang P, Zychlinsky A, de Visser KE, Egeblad M, Kubes P
J Exp Med 2022 Jun 6;219(6) Epub 2022 May 6 doi: 10.1084/jem.20220011. PMID: 35522219Free PMC Article
Bansal A, Simon MC
J Cell Biol 2018 Jul 2;217(7):2291-2298. Epub 2018 Jun 18 doi: 10.1083/jcb.201804161. PMID: 29915025Free PMC Article
Hojman P, Gehl J, Christensen JF, Pedersen BK
Cell Metab 2018 Jan 9;27(1):10-21. Epub 2017 Oct 19 doi: 10.1016/j.cmet.2017.09.015. PMID: 29056514

Recent clinical studies

Etiology

Wilson RL, Taaffe DR, Newton RU, Hart NH, Lyons-Wall P, Galvão DA
Crit Rev Oncol Hematol 2022 Jan;169:103543. Epub 2021 Nov 20 doi: 10.1016/j.critrevonc.2021.103543. PMID: 34808374
Wu Q, Li B, Li Z, Li J, Sun S, Sun S
J Hematol Oncol 2019 Sep 10;12(1):95. doi: 10.1186/s13045-019-0778-6. PMID: 31500658Free PMC Article
Mijanović O, Branković A, Panin AN, Savchuk S, Timashev P, Ulasov I, Lesniak MS
Cancer Lett 2019 May 1;449:207-214. Epub 2019 Feb 20 doi: 10.1016/j.canlet.2019.02.035. PMID: 30796968Free PMC Article
Graham SV
Clin Sci (Lond) 2017 Sep 1;131(17):2201-2221. Epub 2017 Aug 10 doi: 10.1042/CS20160786. PMID: 28798073
Haga RB, Ridley AJ
Small GTPases 2016 Oct;7(4):207-221. Epub 2016 Sep 14 doi: 10.1080/21541248.2016.1232583. PMID: 27628050Free PMC Article

Diagnosis

Paskeh MDA, Entezari M, Mirzaei S, Zabolian A, Saleki H, Naghdi MJ, Sabet S, Khoshbakht MA, Hashemi M, Hushmandi K, Sethi G, Zarrabi A, Kumar AP, Tan SC, Papadakis M, Alexiou A, Islam MA, Mostafavi E, Ashrafizadeh M
J Hematol Oncol 2022 Jun 28;15(1):83. doi: 10.1186/s13045-022-01305-4. PMID: 35765040Free PMC Article
Jia SN, Han YB, Yang R, Yang ZC
Semin Cancer Biol 2022 Nov;86(Pt 3):400-407. Epub 2022 Feb 7 doi: 10.1016/j.semcancer.2022.02.007. PMID: 35183412
Chen Y, McAndrews KM, Kalluri R
Nat Rev Clin Oncol 2021 Dec;18(12):792-804. Epub 2021 Sep 6 doi: 10.1038/s41571-021-00546-5. PMID: 34489603Free PMC Article
Dratwa M, Wysoczańska B, Łacina P, Kubik T, Bogunia-Kubik K
Front Immunol 2020;11:589929. Epub 2020 Nov 19 doi: 10.3389/fimmu.2020.589929. PMID: 33329574Free PMC Article
Xu X, Zhang M, Xu F, Jiang S
Mol Cancer 2020 Nov 24;19(1):165. doi: 10.1186/s12943-020-01276-5. PMID: 33234169Free PMC Article

Therapy

Wang Y, Du J, Wu X, Abdelrehem A, Ren Y, Liu C, Zhou X, Wang S
Mol Cancer 2021 Dec 11;20(1):163. doi: 10.1186/s12943-021-01461-0. PMID: 34895252Free PMC Article
Olejarz W, Kubiak-Tomaszewska G, Chrzanowska A, Lorenc T
Int J Mol Sci 2020 Aug 14;21(16) doi: 10.3390/ijms21165840. PMID: 32823989Free PMC Article
Jiang Y, Wang C, Zhou S
Biochim Biophys Acta Rev Cancer 2020 Apr;1873(2):188361. Epub 2020 Mar 29 doi: 10.1016/j.bbcan.2020.188361. PMID: 32234508
Myers KV, Amend SR, Pienta KJ
Mol Cancer 2019 May 14;18(1):94. doi: 10.1186/s12943-019-1022-2. PMID: 31088471Free PMC Article
Santoiemma PP, Powell DJ Jr
Cancer Biol Ther 2015;16(6):807-20. Epub 2015 Apr 20 doi: 10.1080/15384047.2015.1040960. PMID: 25894333Free PMC Article

Prognosis

Chen P, Wang Y, Li J, Bo X, Wang J, Nan L, Wang C, Ba Q, Liu H, Wang H
Clin Transl Med 2021 Jun;11(6):e462. doi: 10.1002/ctm2.462. PMID: 34185421Free PMC Article
Matulonis UA, Shapira-Frommer R, Santin AD, Lisyanskaya AS, Pignata S, Vergote I, Raspagliesi F, Sonke GS, Birrer M, Provencher DM, Sehouli J, Colombo N, González-Martín A, Oaknin A, Ottevanger PB, Rudaitis V, Katchar K, Wu H, Keefe S, Ruman J, Ledermann JA
Ann Oncol 2019 Jul 1;30(7):1080-1087. doi: 10.1093/annonc/mdz135. PMID: 31046082
Zhang X, Sai B, Wang F, Wang L, Wang Y, Zheng L, Li G, Tang J, Xiang J
Mol Cancer 2019 Mar 13;18(1):40. doi: 10.1186/s12943-019-0959-5. PMID: 30866952Free PMC Article
Peisch SF, Van Blarigan EL, Chan JM, Stampfer MJ, Kenfield SA
World J Urol 2017 Jun;35(6):867-874. Epub 2016 Aug 12 doi: 10.1007/s00345-016-1914-3. PMID: 27518576Free PMC Article
Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E
J Natl Cancer Inst 2014 Jun;106(6):dju124. Epub 2014 May 29 doi: 10.1093/jnci/dju124. PMID: 24875653

Clinical prediction guides

Tang B, Yan R, Zhu J, Cheng S, Kong C, Chen W, Fang S, Wang Y, Yang Y, Qiu R, Lu C, Ji J
Int J Biol Sci 2022;18(1):180-198. Epub 2022 Jan 1 doi: 10.7150/ijbs.64654. PMID: 34975326Free PMC Article
Ortiz A
Semin Cancer Biol 2021 Nov;76:139-142. Epub 2021 Jun 4 doi: 10.1016/j.semcancer.2021.05.032. PMID: 34090999Free PMC Article
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
Läubli H, Borsig L
Front Immunol 2019;10:2120. Epub 2019 Sep 6 doi: 10.3389/fimmu.2019.02120. PMID: 31552050Free PMC Article
Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E
J Natl Cancer Inst 2014 Jun;106(6):dju124. Epub 2014 May 29 doi: 10.1093/jnci/dju124. PMID: 24875653

Recent systematic reviews

Cheng E, Kirley J, Cespedes Feliciano EM, Caan BJ
Cancer Causes Control 2022 Oct;33(10):1219-1246. Epub 2022 Aug 15 doi: 10.1007/s10552-022-01613-7. PMID: 35971021Free PMC Article
Bouleftour W, Guillot A, Magne N
Mol Cancer Ther 2022 Apr 1;21(4):493-501. doi: 10.1158/1535-7163.MCT-21-0846. PMID: 35131876
Ray I, Meira LB, Michael A, Ellis PE
Cancer Metastasis Rev 2022 Mar;41(1):211-242. Epub 2021 Dec 24 doi: 10.1007/s10555-021-10002-6. PMID: 34951691Free PMC Article
Wang X, Wang N, Zhong L, Wang S, Zheng Y, Yang B, Zhang J, Lin Y, Wang Z
Mol Psychiatry 2020 Dec;25(12):3186-3197. Epub 2020 Aug 20 doi: 10.1038/s41380-020-00865-6. PMID: 32820237Free PMC Article
Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E
J Natl Cancer Inst 2014 Jun;106(6):dju124. Epub 2014 May 29 doi: 10.1093/jnci/dju124. PMID: 24875653

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