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Abnormal circulating fatty-acid concentration

MedGen UID:
892372
•Concept ID:
C4021656
•
Finding
Synonym: Abnormality of fatty-acid metabolism
 
HPO: HP:0004359

Definition

A deviation from the normal concentration of a fatty acid in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating fatty-acid concentration

Professional guidelines

PubMed

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation.
Van de Wijer L, van der Heijden WA, Ter Horst R, Jaeger M, Trypsteen W, Rutsaert S, van Cranenbroek B, van Rijssen E, Joosten I, Joosten L, Vandekerckhove L, Schoofs T, van Lunzen J, Netea MG, Koenen HJPM, van der Ven AJAM, de Mast Q
Front Immunol 2021;12:661990. Epub 2021 Apr 19 doi: 10.3389/fimmu.2021.661990. PMID: 33953724Free PMC Article
Treprostinil treatment decreases circulating platelet microvesicles and their procoagulant activity in pediatric pulmonary hypertension.
Bacha NC, Levy M, Guerin CL, Le Bonniec B, Harroche A, Szezepanski I, Renard JM, Gaussem P, Israel-Biet D, Boulanger CM, Smadja DM
Pediatr Pulmonol 2019 Jan;54(1):66-72. Epub 2018 Nov 28 doi: 10.1002/ppul.24190. PMID: 30485728
Diagnostic and therapeutic uses of inhaled nitric oxide in neonatal Ebstein's anomaly.
Atz AM, Munoz RA, Adatia I, Wessel DL
Am J Cardiol 2003 Apr 1;91(7):906-8. doi: 10.1016/s0002-9149(03)00036-5. PMID: 12667588

Recent clinical studies

Etiology

Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.
Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Importance of platelet aggregation in patients with end-stage renal disease.
Martinović Z, Basić-Jukić N, Pavlović DB, Kes P
Acta Clin Croat 2013 Dec;52(4):472-7. PMID: 24696998
Low-flow antegrade cerebral perfusion attenuates early renal and intestinal injury during neonatal aortic arch reconstruction.
Algra SO, Schouten AN, van Oeveren W, van der Tweel I, Schoof PH, Jansen NJ, Haas F
J Thorac Cardiovasc Surg 2012 Dec;144(6):1323-8, 1328.e1-2. Epub 2012 Apr 13 doi: 10.1016/j.jtcvs.2012.03.008. PMID: 22503201
Diagnostic and therapeutic uses of inhaled nitric oxide in neonatal Ebstein's anomaly.
Atz AM, Munoz RA, Adatia I, Wessel DL
Am J Cardiol 2003 Apr 1;91(7):906-8. doi: 10.1016/s0002-9149(03)00036-5. PMID: 12667588
Congenital diaphragmatic hernia: impact of prostanoids in the perioperative period.
Bos AP, Tibboel D, Hazebroek FW, Stijnen T, Molenaar JC
Arch Dis Child 1990 Sep;65(9):994-5. doi: 10.1136/adc.65.9.994. PMID: 2221977Free PMC Article

Diagnosis

Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders.
Karpen SJ, Kelly D, Mack C, Stein P
Hepatol Int 2020 Sep;14(5):677-689. Epub 2020 Jul 11 doi: 10.1007/s12072-020-10070-w. PMID: 32653991
Diagnostic and therapeutic uses of inhaled nitric oxide in neonatal Ebstein's anomaly.
Atz AM, Munoz RA, Adatia I, Wessel DL
Am J Cardiol 2003 Apr 1;91(7):906-8. doi: 10.1016/s0002-9149(03)00036-5. PMID: 12667588
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
Scott AC, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J, Coats AJ, Piepoli MF
Circulation 2002 Jul 9;106(2):214-20. doi: 10.1161/01.cir.0000021603.36744.5e. PMID: 12105161
Deep hypothermia without extracorporeal circulation in surgery of congenital cardiac defects.
Litasova EE, Lomivirotov VN, Gorbatich JN, Shunkin AV, Vlassov JA
J Cardiovasc Surg (Torino) 1994 Feb;35(1):45-52. PMID: 8120077
Control of glycaemia.
Gerich JE
Baillieres Clin Endocrinol Metab 1993 Jul;7(3):551-86. doi: 10.1016/s0950-351x(05)80207-1. PMID: 8379904

Therapy

Importance of platelet aggregation in patients with end-stage renal disease.
Martinović Z, Basić-Jukić N, Pavlović DB, Kes P
Acta Clin Croat 2013 Dec;52(4):472-7. PMID: 24696998
Low-flow antegrade cerebral perfusion attenuates early renal and intestinal injury during neonatal aortic arch reconstruction.
Algra SO, Schouten AN, van Oeveren W, van der Tweel I, Schoof PH, Jansen NJ, Haas F
J Thorac Cardiovasc Surg 2012 Dec;144(6):1323-8, 1328.e1-2. Epub 2012 Apr 13 doi: 10.1016/j.jtcvs.2012.03.008. PMID: 22503201
Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers.
Wolfe BE, Jimerson DC, Orlova C, Mantzoros CS
Clin Endocrinol (Oxf) 2004 Sep;61(3):332-8. doi: 10.1111/j.1365-2265.2004.02101.x. PMID: 15355449
Oral prostaglandin E2 in ductus-dependent pulmonary circulation.
Silove ED, Coe JY, Shiu MF, Brunt JD, Page AJ, Singh SP, Mitchell MD
Circulation 1981 Mar;63(3):682-8. doi: 10.1161/01.cir.63.3.682. PMID: 7460252
Acute anaphylaxis associated with serum complement depletion.
Tannenbaum H, Ruddy S, Schur PH
J Allergy Clin Immunol 1975 Sep;56(3):226-34. doi: 10.1016/0091-6749(75)90094-9. PMID: 50336

Prognosis

Circulating Bile Acid Profiles: A Need for Further Examination.
Qi L, Tian Y, Chen Y
J Clin Endocrinol Metab 2021 Oct 21;106(11):3093-3112. doi: 10.1210/clinem/dgab531. PMID: 34279029
Diagnostic and therapeutic uses of inhaled nitric oxide in neonatal Ebstein's anomaly.
Atz AM, Munoz RA, Adatia I, Wessel DL
Am J Cardiol 2003 Apr 1;91(7):906-8. doi: 10.1016/s0002-9149(03)00036-5. PMID: 12667588
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
Scott AC, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J, Coats AJ, Piepoli MF
Circulation 2002 Jul 9;106(2):214-20. doi: 10.1161/01.cir.0000021603.36744.5e. PMID: 12105161
Favorable response of Eisenmenger syndrome to inhaled nitric oxide during pregnancy.
Goodwin TM, Gherman RB, Hameed A, Elkayam U
Am J Obstet Gynecol 1999 Jan;180(1 Pt 1):64-7. doi: 10.1016/s0002-9378(99)70151-1. PMID: 9914580
Alpha-fetoprotein in abortion.
Seppälä M, Ruoslahti E
Br Med J 1972 Dec 30;4(5843):769-71. doi: 10.1136/bmj.4.5843.769. PMID: 4646508Free PMC Article

Clinical prediction guides

Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.
Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
Scott AC, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J, Coats AJ, Piepoli MF
Circulation 2002 Jul 9;106(2):214-20. doi: 10.1161/01.cir.0000021603.36744.5e. PMID: 12105161
Pregnancy induced hypertension: a role for peroxidation in microvillus plasma membranes.
Cester N, Staffolani R, Rabini RA, Magnanelli R, Salvolini E, Galassi R, Mazzanti L, Romanini C
Mol Cell Biochem 1994 Feb 23;131(2):151-5. doi: 10.1007/BF00925951. PMID: 8035780
Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes.
Press M, Tamborlane WV, Sherwin RS
N Engl J Med 1984 Mar 29;310(13):810-5. doi: 10.1056/NEJM198403293101302. PMID: 6700669
Alpha-fetoprotein in abortion.
Seppälä M, Ruoslahti E
Br Med J 1972 Dec 30;4(5843):769-71. doi: 10.1136/bmj.4.5843.769. PMID: 4646508Free PMC Article

Recent systematic reviews

Influence of Statins on Circulating Inflammatory Cytokines in Patients With Abnormal Glucose Homeostasis: A Meta-analysis of Data From Randomized Controlled Trials.
Milajerdi A, Sadeghi A, Mousavi SM, Larijani B, Esmaillzadeh A
Clin Ther 2020 Feb;42(2):e13-e31. Epub 2020 Jan 17 doi: 10.1016/j.clinthera.2019.12.009. PMID: 31955966

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