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Viral hemorrhagic fever

MedGen UID:
9213
Concept ID:
C0019104
Disease or Syndrome
Synonyms: Fever, Viral Hemorrhagic; Fevers, Viral Hemorrhagic; Hemorrhagic Fever, Viral; Hemorrhagic Fevers, Viral; Viral Hemorrhagic Fever; Viral Hemorrhagic Fevers
SNOMED CT: VHF - Viral hemorrhagic fever (240523007); Viral hemorrhagic fever (240523007)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018087
Orphanet: ORPHA341

Definition

Viral hemorrhagic fever is a group of recently discovered contagious viral infections characterized by severe, multiple, and often fatal hemorrhages. African fevers include Lassa fever discovered in 1969, Marburg's disease that first occurred in 1967, and Ebola fever that appeared in 1976. Other viruses may also cause hemorrhagic fevers (for example, arbovirus fever). [from ORDO]

Professional guidelines

PubMed

Lashgari NA, Roudsari NM, Khayatan D, Samani N, Eskandari Rad N, Mortazavi M, Abdolghaffari AH, Momtaz S
Mini Rev Med Chem 2023;23(15):1575-1589. doi: 10.2174/1389557523666230202111337. PMID: 36733245
Murin CD, Gunn BM, Parren PWHI, Kobinger GP
Front Immunol 2022;13:859919. Epub 2022 Feb 18 doi: 10.3389/fimmu.2022.859919. PMID: 35251051Free PMC Article
Clément C, Adhikari NKJ, Lamontagne F
Infect Dis Clin North Am 2019 Mar;33(1):247-264. doi: 10.1016/j.idc.2018.10.013. PMID: 30712765

Recent clinical studies

Etiology

Klitting R, Mehta SB, Oguzie JU, Oluniyi PE, Pauthner MG, Siddle KJ, Andersen KG, Happi CT, Sabeti PC
Curr Top Microbiol Immunol 2023;440:23-65. doi: 10.1007/82_2020_212. PMID: 32418034
Tuells J, Henao-Martínez AF, Franco-Paredes C
Arch Med Res 2022 Nov;53(7):649-657. Epub 2022 Oct 28 doi: 10.1016/j.arcmed.2022.10.005. PMID: 36404585
Paquet D, Jung L, Trawinski H, Wendt S, Lübbert C
Dtsch Arztebl Int 2022 Jun 7;119(22):400-407. doi: 10.3238/arztebl.m2022.0182. PMID: 35469592Free PMC Article
Iannetta M, Di Caro A, Nicastri E, Vairo F, Masanja H, Kobinger G, Mirazimi A, Ntoumi F, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):977-1002. doi: 10.1016/j.idc.2019.08.003. PMID: 31668201
Fillâtre P, Revest M, Tattevin P
Med Mal Infect 2019 Nov;49(8):574-585. Epub 2019 Oct 10 doi: 10.1016/j.medmal.2019.09.005. PMID: 31607406

Diagnosis

Paquet D, Jung L, Trawinski H, Wendt S, Lübbert C
Dtsch Arztebl Int 2022 Jun 7;119(22):400-407. doi: 10.3238/arztebl.m2022.0182. PMID: 35469592Free PMC Article
Iannetta M, Di Caro A, Nicastri E, Vairo F, Masanja H, Kobinger G, Mirazimi A, Ntoumi F, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):977-1002. doi: 10.1016/j.idc.2019.08.003. PMID: 31668201
Fillâtre P, Revest M, Tattevin P
Med Mal Infect 2019 Nov;49(8):574-585. Epub 2019 Oct 10 doi: 10.1016/j.medmal.2019.09.005. PMID: 31607406
Racsa LD, Kraft CS, Olinger GG, Hensley LE
Clin Infect Dis 2016 Jan 15;62(2):214-9. Epub 2015 Sep 9 doi: 10.1093/cid/civ792. PMID: 26354968Free PMC Article
Bente DA, Forrester NL, Watts DM, McAuley AJ, Whitehouse CA, Bray M
Antiviral Res 2013 Oct;100(1):159-89. Epub 2013 Jul 29 doi: 10.1016/j.antiviral.2013.07.006. PMID: 23906741

Therapy

Raabe V, Mehta AK, Evans JD; Science Working Group of the National Emerging Special Pathogens Training and Education Center (NETEC) Special Pathogens Research Network (SPRN)
Int J Infect Dis 2022 Jun;119:187-200. Epub 2022 Apr 6 doi: 10.1016/j.ijid.2022.04.004. PMID: 35395384
Arts RJW, Moorlag SJCFM, Novakovic B, Li Y, Wang SY, Oosting M, Kumar V, Xavier RJ, Wijmenga C, Joosten LAB, Reusken CBEM, Benn CS, Aaby P, Koopmans MP, Stunnenberg HG, van Crevel R, Netea MG
Cell Host Microbe 2018 Jan 10;23(1):89-100.e5. doi: 10.1016/j.chom.2017.12.010. PMID: 29324233
Reynolds P, Marzi A
Virus Genes 2017 Aug;53(4):501-515. Epub 2017 Apr 26 doi: 10.1007/s11262-017-1455-x. PMID: 28447193Free PMC Article
Smith DR, Holbrook MR, Gowen BB
Antiviral Res 2014 Dec;112:59-79. Epub 2014 Oct 18 doi: 10.1016/j.antiviral.2014.10.001. PMID: 25448088
Monath TP
Expert Rev Vaccines 2005 Aug;4(4):553-74. doi: 10.1586/14760584.4.4.553. PMID: 16117712

Prognosis

Paquet D, Jung L, Trawinski H, Wendt S, Lübbert C
Dtsch Arztebl Int 2022 Jun 7;119(22):400-407. doi: 10.3238/arztebl.m2022.0182. PMID: 35469592Free PMC Article
Al-Tawfiq JA, Memish ZA
Vector Borne Zoonotic Dis 2018 Feb;18(2):75-81. Epub 2018 Jan 10 doi: 10.1089/vbz.2017.2209. PMID: 29319426
Salvato MS, Lukashevich IS, Yang Y, Medina-Moreno S, Djavani M, Bryant J, Rodas JD, Zapata JC
Methods Mol Biol 2018;1604:279-290. doi: 10.1007/978-1-4939-6981-4_22. PMID: 28986843
Baseler L, Chertow DS, Johnson KM, Feldmann H, Morens DM
Annu Rev Pathol 2017 Jan 24;12:387-418. doi: 10.1146/annurev-pathol-052016-100506. PMID: 27959626
Salvaggio MR, Baddley JW
Dermatol Clin 2004 Jul;22(3):291-302, vi. doi: 10.1016/j.det.2004.03.003. PMID: 15207310

Clinical prediction guides

Lee YC, Jung SH, Kumar A, Shim I, Song M, Kim MS, Kim K, Myung W, Park WY, Won HH
J Biomed Inform 2023 May;141:104361. Epub 2023 Apr 11 doi: 10.1016/j.jbi.2023.104361. PMID: 37054960
Paquet D, Jung L, Trawinski H, Wendt S, Lübbert C
Dtsch Arztebl Int 2022 Jun 7;119(22):400-407. doi: 10.3238/arztebl.m2022.0182. PMID: 35469592Free PMC Article
Salvato MS, Lukashevich IS, Yang Y, Medina-Moreno S, Djavani M, Bryant J, Rodas JD, Zapata JC
Methods Mol Biol 2018;1604:279-290. doi: 10.1007/978-1-4939-6981-4_22. PMID: 28986843
Reynolds P, Marzi A
Virus Genes 2017 Aug;53(4):501-515. Epub 2017 Apr 26 doi: 10.1007/s11262-017-1455-x. PMID: 28447193Free PMC Article
Baseler L, Chertow DS, Johnson KM, Feldmann H, Morens DM
Annu Rev Pathol 2017 Jan 24;12:387-418. doi: 10.1146/annurev-pathol-052016-100506. PMID: 27959626

Recent systematic reviews

Esser HJ, Mögling R, Cleton NB, van der Jeugd H, Sprong H, Stroo A, Koopmans MPG, de Boer WF, Reusken CBEM
Parasit Vectors 2019 May 27;12(1):265. doi: 10.1186/s13071-019-3515-7. PMID: 31133059Free PMC Article
Ergönül Ö, Keske Ş, Çeldir MG, Kara İA, Pshenichnaya N, Abuova G, Blumberg L, Gönen M
Emerg Infect Dis 2018 Sep;24(9):1642-1648. doi: 10.3201/eid2409.171709. PMID: 30124196Free PMC Article
Pshenichnaya NY, Leblebicioglu H, Bozkurt I, Sannikova IV, Abuova GN, Zhuravlev AS, Barut S, Shermetova MB, Fletcher TE
Int J Infect Dis 2017 May;58:58-64. Epub 2017 Feb 27 doi: 10.1016/j.ijid.2017.02.019. PMID: 28249811Free PMC Article

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