GEO DataSets

Analysis of cells exposed to the radiomimetic enediyne antibiotics calicheamicin, esperamicin A1, and neocarzinostatin. These enediynes bind specifically to DNA and generate single- and double-strand DNA breaks. Results provide insight into the response to DNA damage.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 6 agent sets

Platform:

GPL90

Series:

GSE5301

18 Samples

Download data

Analysis of Saccharomyces cerevisiae cells subjected to anti-malaria drug quinine (QN) at concentration that exerted a very slight effect on cellular growth. Results provide insight into the molecular mechanisms underlying QN action and the host response to the drug.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL90

Series:

GSE18037

4 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae wild type cells grown under reduced oxygen tension. Heme synthesis requires oxygen, and yeast grown anaerobically exhibit an increased uptake of hemin. Results provide insight into the molecular mechanisms regulating heme uptake.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 growth protocol sets

Platform:

GPL90

Series:

GSE9514

4 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae mutant cells lacking aminolevulinic acid (ALA) synthase. ALA synthase catalyzes the first step of heme biosynthesis. Heme uptake is induced by heme starvation in S. cerevisiae. Results provide insight into the molecular mechanisms regulating heme uptake.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 growth protocol sets

Platform:

GPL90

Series:

GSE9514

4 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae, strain Vin13, subjected to ethanol levels up to 10% during a 15-day wine fermentation. Results provide insight into molecular mechanisms underlying the adaptive response of yeast to the long-term environmental stresses present during alcoholic fermentation.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, transformed count, 6 stress, 7 time sets

Platform:

GPL90

Series:

GSE8536

21 Samples

Download data: CEL

Analysis of strain S288C cells subjected to pterostilbene at the IC50 concentration (70uM) for one generation (3h). Pterostilbene, an analog of resveratrol, is a phytoalexin exhibiting potent antifungal activity. Results provide insight into the molecular pathways affected by pterostilbene.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL90

Series:

GSE10554

6 Samples

Download data: CEL

Analysis of temperature sensitive Abf1 mutant cells subjected to a temperature of 37 degrees C to dissociate the mutant protein from its DNA binding sites. Results provide insight into the contribution of this general regulatory factor to transcription genome-wide.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL90

Series:

GSE6073

6 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae cells treated with the antifungal compound sampangine. Sampangine exhibits strong inhibitory activity against opportunistic fungal pathogens such as Candida albicans. Using S. cerevisiae as a model, results provide insight into sampangine's mechanism of action.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL90

Series:

GSE10073

6 Samples

Download data: CEL

Analysis of not1-2 spt3 double mutant cells. NOT1 encodes the scaffold subunit of the Ccr4-Not transcription factor complex. SPT3 encodes a transcription factor. The temperature sensitive not1-2 mutant exhibits transcriptional defects that are suppressed by the deletion of SPT3.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 4 genotype/variation sets

Platform:

GPL90

Series:

GSE9432

8 Samples

Download data: CEL, CHP

Analysis of several Saccharomyces cerevisiae mutants each deficient in one of various ribosomal proteins. S. cerevisiae contains many duplicated genes encoding ribosomal proteins. Results provide insight into the unique role of each member of a pair of ribosomal protein paralogs.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 12 genotype/variation sets

Platform:

GPL90

Series:

GSE8761

24 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae cultures at various time points up to 120 minutes following treatment with the oxidant cumene hydroperoxide (CHP). Results provide insight into molecular mechanisms underlying the response of the yeast S. cerevisiae to oxidative stress.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, transformed count, 2 agent, 8 time sets

Platform:

GPL90

Series:

GSE7645

48 Samples

Download data: CEL

Analysis of Saccharomyces cerevisiae strain 4073 cultures treated with gentamicin. Gentamicin is an antibiotic used against gram-negative bacterial infections. Its usefulness is limited by nephrotoxicity. Results provide insight into the molecular mechanisms underlying gentamicin's renal toxicity.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL90

Series:

GSE7188

8 Samples

Download data: CEL, CHP

Analysis of chemostat cultures sparged with 79% or 100% carbon dioxide (CO2). During fermentation and ethanol production, CO2 is produced, saturating the fermentative broth. Results provide insight into the mechanisms underlying CO2 stress.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 4 dose, 2 growth protocol sets

Platform:

GPL90

Series:

GSE8900

18 Samples

Download data: CEL, EXP

Analysis of anaerobic chemostat cultures of Saccharomyces cerevisae exposed to one of several weak organic acids. Weak organic acids are used as preservatives in food and beverages. Yeasts are able to proliferate at the maximum legal dosage of such preservatives.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 5 stress sets

Platform:

GPL90

Series:

GSE5926

15 Samples

Download data: CEL

Analysis of the response of quiescent stb3 null cells to glucose. STB3 encodes a protein that binds to the Ribosomal RNA Processing Element, a DNA sequence motif that regulates genes needed for growth. Results provide insight into Stb3’s role during the transition from quiescence to rapid growth.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, transformed count, 2 genotype/variation, 2 growth protocol sets

Platform:

GPL90

Series:

GSE8379

8 Samples

Download data: CEL

Comparison of commercially prepared dry active yeast and desiccated preparations of the Saccharomyces cerevisiae laboratory strain BY4743. The yeast specimens were dried by different regimens. Results provide insight into the molecular response of yeast to water removal.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 specimen, 2 stress sets

Platform:

GPL90

Series:

GSE1314

9 Samples

Download data: CEL, DAT, EXP

Analysis of Saccharomyces cerevisiae BY4743 cells subjected to controlled air-drying and subsequent rehydration for up to 360 minutes. Results provide insight into the molecular response of yeast to water deficit.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 7 other, 3 protocol sets

Platform:

GPL90

Series:

GSE1313

21 Samples

Download data: CEL, DAT, EXP

Analysis of Saccharomyces cerevisiae BY4743 cells subjected to controlled air-drying and subsequent rehydration for up to 360 minutes. Results provide insight into the molecular response of yeast to water deficit.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 7 other, 3 protocol sets

Platform:

GPL90

Series:

GSE1312

21 Samples

Download data: CEL, DAT, EXP

Analysis of Saccharomyces cerevisiae BY4743 cells subjected to controlled air-drying and subsequent rehydration for up to 360 minutes. Results provide insight into the molecular response of yeast to water deficit.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 7 other, 3 protocol sets

Platform:

GPL90

Series:

GSE1311

21 Samples

Download data: CEL, DAT, EXP

Analysis of Mre11 deficient cells at meiotic prophase during sporulation. Mre11 is important in homologous recombination, repair of DNA double strand breaks, activation of damage-induced checkpoint, and telomere maintenance. Results provide insight into the role of Mre11 in spore development.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 development stage, 4 genotype/variation sets

Platform:

GPL90

Series:

GSE6620

8 Samples

Download data: CEL