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Spontaneous SCC induced by the somatic inactivation of Rb1 and Trp53 tumor suppressors in mouse stratified epithelia
PubMed Similar studies Analyze with GEO2R
p107 acts as a tumor suppressor in pRb-deficient epidermis.
pRb p107 double deficient skin
PubMed Similar studies GEO Profiles Analyze DataSet
E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis
p53 deletion induces liver carcinoma with bilineal differentiation
Mouse Tumor Dataset
CAFs are activated in incipient neoplasia to orchestrate tumor promoting inflammation in an NF-κB-dependent manner.
Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis
p53 family members in myogenic differentiation and rhabdomyosarcoma development
Myoblast differentiation and p53 family members
A Novel Tumor suppressor network in squamous malignancies
PubMed Full text in PMC Similar studies Analyze with GEO2R
Genomic profiles of mouse liver tissue harboring deletion of RB and/or p53, untreated or post-hepatocarcinogen treatment [CGH data]
Genomic profiles of mouse liver tissue harboring deletion of RB and/or p53, untreated or post-hepatocarcinogen treatment [expression data]
Gene expression profiles of mouse liver tissue harboring deletion of RB and/or p53, untreated or post-hepatocarcinogen treatment
miRNA expression profiling in squamous cell carcinoma (SCC)
Ablation of Cdh1 and Trp53 in the uterus reveals novel mechanisms controlling tumor microenvironment in endometrial cancer.
Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy (testing dataset)
Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy (training dataset)
Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells
PubMed Full text in PMC Similar studies SRA Run Selector
Stem cell quiescence acts as a tumor suppressor mechanism in hair follicle initiated squamous tumors
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