Similar studies for GEO DataSets (Select 200015070) - GEO DataSets

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Items: 19

Select item 2000150701.

Expression Profiles of 15(S)-HETE treated RAW 264.7 cells

(Submitter supplied) Hemozoin phagocytosis results in immunomodulation. This study was designed to explore gene expression responses to 15(S)-HETE in LPS-stimulated RAW 264.7 cells.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2995
6 Samples

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Series

Accession:: GSE15070

ID:: 200015070

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000132812.

Expression profiles of beta-hematin (BH)- or 4-hydroxy-2-nonenal (HNE)-treated RAW 264.7 cells

(Submitter supplied) Hemozoin phagocytosis results in immunomodulation. In the present study, gene expression profiles were analyzed to identify transcriptional changes associated with two of the individual components of Hz in a model macrophage cell line. LPS-stimulated RAW 264.7 cells were exposed to the synthetic form of Hz, β-hematin (BH, 0.1 mg/mL) and HNE (35 μM) for 6 or 24 h. Keywords: variable treatment

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL6246 GPL2995
24 Samples

Download data: CEL

Series

Accession:: GSE13281

ID:: 200013281

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Select item 2000096323.

Gene expression profiles of RAW264.7 macrophage cells treated with Paeony root-derived compounds

(Submitter supplied) Paeony root has long been used for its anti-inflammatory effects. In this study, the effects of albiflorin, paeoniflorin, and paeonol, compounds from paeony root, on gene expression profiles were examined in macrophages. The RAW264.7 macrophages were treated with LPS in the presence or absence of albiflorin, paeoniflorin, or paeonol. Global mRNA expression levels were detected by using an oligonucleotide microarray platform covering the mouse whole genome. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2995
33 Samples

Download data: TXT

Series

Accession:: GSE9632

ID:: 200009632

Select item 2000215484.

Gene Expression Profiles of RAW264.7 Macrophages Stimulated with Two Commonly Used Preparations of LPS

(Submitter supplied) Background: Toll-like family of receptors recognizes pathogen-associated molecular patterns (PAMPs) from different organisms. TLR4 is the receptor for bacterial lipopolysaccharide (LPS), dsRNA viral mimic poly(I:C) binds to TLR3, and bacterial CpG DNA signals through TLR9. TLR4 signaling is mediated by adaptor molecules Myd88 and TRIF while TLR3 pathway involves only the TRIF adaptor and TLR9 signals solely through Myd88. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL891
46 Samples

Download data: TXT

Series

Accession:: GSE21548

ID:: 200021548

Select item 2000943175.

Gene expression analysis of macrophage response to infection with Streptococcus oralis or to treatment with hydrogen peroxide

(Submitter supplied) We compared the gene expression patterns of macrophages infected with S. oralis wild type and SpxB KO, a strain that does not produce H2O2.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL21810
8 Samples

Download data: TXT

Series

Accession:: GSE94317

ID:: 200094317

Select item 2001039586.

Transcript dynamics in classically and alternatively activated macrophages

(Submitter supplied) Using RNA-seq, we have reported that signaling crosstalk among IFN-γ and LPS is integrated at the level of transcriptome and have associated with TFs and TcoFs changes. In addition, we also argue that the transcriptional differences between BMDMs and RAW264.7 macrophage cell line as well as IL-4 and IL-13 on M2 macrophages activation.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
25 Samples

Download data: TAB

Series

Accession:: GSE103958

ID:: 200103958

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000020027.

CstF-64 Influenced Gene Expression

(Submitter supplied) Triplicate samples of RAW 264.7 murine macrophages either untreated, stimulated with 100 ng/ml LPS for 18 hours, or constituitively over-expressing CstF-64 were analyzed by microarray using Affymetrix murine gene chip 430A. Keywords = RAW 264.7 macrophages Keywords = LPS Keywords = CstF-64 Keywords: repeat sample

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1285
Platform:: GPL339
9 Samples

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Series

Accession:: GSE2002

ID:: 200002002

Select item 12858.

Macrophage response to lipopolysaccharide and CstF-64 overexpression

Analysis of RAW 264.7 macrophages treated with 100 ng/ml lipopolysaccharide (LPS) for 18 hours, or overexpressing polyadenylation factor CstF-64. LPS treatment increases CstF-64 expression. Results provide insight into post-transcriptional mechanisms affected by LPS in macrophages.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL339
Series:: GSE2002
9 Samples

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DataSet

Accession:: GDS1285

ID:: 1285

Select item 2000014059.

LPS-induced and E. coli-induced gene expression in wildtype and MyD88-/- mouse macrophages

(Submitter supplied) Comparison of gene expression in wildtype and MyD88-/- C57BL/6J mouse macrophages treated with 10 ng/mL LPS for 2 hours versus media treated control macrophages, and, wildtype and MyD88-/- C57BL/6J mouse macrophages treated with live E. coli bacteria (log phase; 1 bact per 1 macrophage) for 2 hours versus media treated control macrophages. Cells from 4 mice of each geneotype were used and each individual provided its own control. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS1705 GDS1706
Platform:: GPL1226
31 Samples

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Series

Accession:: GSE1405

ID:: 200001405

Select item 170610.

MyD88-deficient macrophage response to lipopolysaccharide and E. coli (dye swap)

Analysis of MyD88 null mutant macrophages treated with LPS or live E. coli. MyD88 transduces cell signaling events downstream of Toll-like receptors, a key component of host defense. Results suggest most of the host response to endotoxin or live bacteria is actually regulated independently of MyD88.

Organism:: Mus musculus

Type:: Expression profiling by array, log2 ratio, 2 agent, 2 genotype/variation sets

Platform:: GPL1226
Series:: GSE1405
15 Samples

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DataSet

Accession:: GDS1706

ID:: 1706

Select item 170511.

MyD88-deficient macrophage response to lipopolysaccharide and E. coli

Organism:: Mus musculus

Type:: Expression profiling by array, log2 ratio, 2 agent, 2 genotype/variation sets

Platform:: GPL1226
Series:: GSE1405
16 Samples

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DataSet

Accession:: GDS1705

ID:: 1705

Select item 20001874012.

Luteolin has anti-inflammatory and neurotrophic effects on microglia

(Submitter supplied) Our aim was to identify genes that were differentially expressed in microglia stimulated with Lipopolysaccharide, Luteolin, or both. Affymetrix microarrays were used to analyze RNA samples

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3613
Platform:: GPL1261
12 Samples

Download data: CEL

Series

Accession:: GSE18740

ID:: 200018740

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 361313.

Luteolin effect on pro-inflammatory challenged microglial cell line

Analysis of lipopolysaccharide-activated microglial BV-2 cells treated with luteolin, a plant derived flavonoid. Luteolin possesses the ability to scavenge oxygen and nitrogen species, and exhibits anti-inflammatory activities. Results provide insight into the immuno-modulatory effects of luteolin.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 agent sets

Platform:: GPL1261
Series:: GSE18740
12 Samples

Download data: CEL

DataSet

Accession:: GDS3613

ID:: 3613

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20000862114.

LPS tolerance in macrophages

(Submitter supplied) Among the multiple mechanisms that control the intensity and duration of macrophage activation, the development of a state of refractoriness to a second stimulation in cells treated with LPS has long been recognized. Release of inhibitory cytokines and alterations in intracellular signaling pathways may be involved in the development of LPS tolerance. Although a number of molecules have been implicated, a detailed picture of the molecular changes in LPS tolerance is still missing. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
12 Samples

Download data: CEL

Series

Accession:: GSE8621

ID:: 200008621

Select item 20002008715.

Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines

(Submitter supplied) To provide a global perspective on the relationships between macrophage activation programs and to understand how certain pathogens circumvent them, we used transcriptional profiling by genome wide microarray analysis to compare the responses of mouse macrophages following exposure to the intracellular parasites Trypanosoma cruzi and Leishmania mexicana, the bacterial product lipopolysaccharide (LPS), and the cytokines IFNG, TNF, IFNB, IL-4, IL-10, and IL-17. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7275
111 Samples

Download data: GPR

Series

Accession:: GSE20087

ID:: 200020087

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000496416.

Gene expression of RAW 264.7 cells treated with LPS, ISO, PGE2, LPS PLUS ISO, and LPS PLUS PGE2

(Submitter supplied) LPS plus ISO and LPS plus PGE2 had non-additive effects on gene expression in RAW 264.7 cells Keywords: time course

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL254
88 Samples

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Series

Accession:: GSE4964

ID:: 200004964

Select item 20000496217.

Gene expression of RAW 264.7 cells treated with LPS, IFG, 2MA, LPS PLUS IFG, and LPS PLUS 2MA

(Submitter supplied) LPS plus IFG and LPS plus 2MA had non-additive effects on gene expression in RAW 264.7 cells Keywords: time course

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL254
90 Samples

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Series

Accession:: GSE4962

ID:: 200004962

Select item 20000109818.

Effect of LPS and LPS-binding protein treatment on RAW 264.4 cells

(Submitter supplied) All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RAW 264.4 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL254
36 Samples

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Series

Accession:: GSE1098

ID:: 200001098

Select item 20001216119.

Transcriptome profiling of control and TNFalpha treated HepG2 cells

(Submitter supplied) The proinflammatory cytokine, TNFalpha is critical in maintaining liver homeostasis since it is a major determiner of hepatocyte life and death. Considering this, gene transcription profiling was examined in control and TNFalpha treated HepG2 cells. Results indicated that TNFalpha could significantly alter the expression of a significant number of genes; most of them were functionally distributed among molecular functions like catalytic activity, binding, molecular transducer activity, transporter activity, translation and transcription regulator activities or enzyme regulator activity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE12161

ID:: 200012161

PubMed Full text in PMC Similar studies Analyze with GEO2R

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