U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.

microRNA profiles of activated and resting T cells and their exosomes

(Submitter supplied) Microarray analysis of exosomal and cellular miRNAs in activated and resting primary human T lymphoblasts
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14767
8 Samples
Download data: TXT
Series
Accession:
GSE50953
ID:
200050953
2.

mRNA and miRNA profiles of activated and resting T cells and their exosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL14767 GPL6480
16 Samples
Download data: TXT
Series
Accession:
GSE50972
ID:
200050972
3.

mRNA profiles of activated and resting T cells and their exosomes

(Submitter supplied) Microarray analysis of exosomal and cellular mRNAs in activated and resting primary human T lymphoblasts
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5639
Platform:
GPL6480
8 Samples
Download data: TXT
Series
Accession:
GSE50971
ID:
200050971
4.
Full record GDS5639

Phorbol myristate acetate plus ionomycin activation effect on primary T lymphoblasts and their exosomes

Analysis of primary T lymphoblasts and derived exosomes after activation with PMA plus ionomycin. Exosomes contain specific RNA species and can be functionally transferred to recipient cells. Results provide insight into molecular mechanisms underlying the selective sorting of RNA into exosomes.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell type, 2 protocol sets
Platform:
GPL6480
Series:
GSE50971
8 Samples
Download data: TXT
5.

The DNA-repair protein APE1 contributes with hnRNPA2B1 to motif-enriched miRNA secretion

(Submitter supplied) The base excision repair (BER) Apurinic/apyrimidinic endonuclease 1 (APE1) enzyme is endowed with several non-repair activities, such as the cell response to genotoxic stress, the regulation of gene expression and miRNAs processing. We recently demonstrated that APE1 can be actively secreted by mammalian cells through exosomes. The role of APE1 in exosomes is still unknown, especially regarding the molecular mechanism involving small non-coding RNAs vesicular secretion. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL24676
16 Samples
Download data: TXT
Series
Accession:
GSE230874
ID:
200230874
6.

Gene expression profiling of mouse bone marrow-derived macrophages (RNA-Seq)

(Submitter supplied) Bone marrow (BM) cells were obtained by flushing the long bones of 8-week old C57BL/6 mice. BM cells were then were plated in macrophage SFM medium (Life Technologies) supplemented with penicillin-streptomycin and CSF-1 (Peprotech, 100 ng/ml) and cultured for one week to allow macrophage differentiation. BMDMs were polarized by adding IL-4 to the medium (40 ng/ml, Peprotech) for 72h or left untreated.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL17021
8 Samples
Download data: GTF, TXT
Series
Accession:
GSE58283
ID:
200058283
7.

Temporal Dynamics of Human Cerebrospinal Fluid Vesicle microRNAs

(Submitter supplied) To determine whether the microRNA content of CSF vesicles changes throughout life we performed experiments including miRNA microarrays. Hierarchical clustering analysis indicated that the miRNA content of CSF vesicles changes when patients less than 2 years are compared to those older than 70 years of age.
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL16384
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE57713
ID:
200057713
8.

Analysis of miRNAs in MCF7 cells regulated by LSD1

(Submitter supplied) Lysine specific demethylase 1 (LSD1) is an important histone demethylase that mediates metastasis in luminal breast cancer. Thus, the characterization of miRNAs in MCF7 cells regulated by LSD1 is imperative in clarifying intercellular signaling.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL24676
9 Samples
Download data: XLSX
Series
Accession:
GSE218200
ID:
200218200
9.

Analysis of exosomal miRNAs in MCF7 cells regulated by LSD1

(Submitter supplied) Lysine specific demethylase 1 (LSD1) is an important histone demethylase that mediates metastasis in luminal breast cancer. Exosomes play a major role in cell-to-cell communication. Thus, the characterization of miRNAs of exosome in MCF7 cells regulated by LSD1 is imperative in clarifying intercellular signaling.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL24676
9 Samples
Download data: XLSX
Series
Accession:
GSE212291
ID:
200212291
10.

miRNA signatures of intracellular and extracellular fractions from cancer cell lines

(Submitter supplied) For the purpose of finding a novel tumor marker, we conducted microRNA profiling analysis in fractions of cells, exosomes, and culture medium from seven cancer cell lines. Ranking data of the intracellular and extracellular microRNAs obtained by microarray analysis, we found that let-7 microRNA family are rich in all fractions from AZ-P7a cells, a metastatic gastric cancer cell line.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL14767
41 Samples
Download data: TXT
Series
Accession:
GSE21350
ID:
200021350
11.

Expression data from normal melanocyte, melanoma cells and their exosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
synthetic construct; Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL570 GPL8786
15 Samples
Download data: CEL
Series
Accession:
GSE35389
ID:
200035389
12.

Expression data from normal melanocyte, melanoma cells and their exosomes (mRNA)

(Submitter supplied) Exosomes are small membraneous vesicles secreted into body fluids by tumors. Tumor exosomes contain intact and functional mRNAs, small RNAs (including miRNAs), and proteins that can alter the cellular environment to favor tumor growth. Further exploration into the molecular profiling of exosomes may increase our understanding of their roles in melanoma progression in vivo, and may have potential application in biomarker studies. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
8 Samples
Download data: CEL
Series
Accession:
GSE35388
ID:
200035388
13.

Expression data from normal melanocyte, melanoma cells and their exosomes (microRNA)

(Submitter supplied) Exosomes are small membraneous vesicles secreted into body fluids by tumors. Tumor exosomes contain intact and functional mRNAs, small RNAs (including miRNAs), and proteins that can alter the cellular environment to favor tumor growth. Further exploration into the molecular profiling of exosomes may increase our understanding of their roles in melanoma progression in vivo, and may have potential application in biomarker studies. more...
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8786
7 Samples
Download data: CEL
Series
Accession:
GSE35387
ID:
200035387
14.

Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq

(Submitter supplied) To identify HNRNPA2B1 binding sites on endogenous nuclear RNAs, we performed HITS-CLIP for endogenous HNRNPA2B1 and RNA-seq to analyze the nuclear RNA under either METTL3 or HNRNPA2B1 depletion.
Organism:
Homo sapiens
Type:
Other; Expression profiling by high throughput sequencing
Platform:
GPL11154
14 Samples
Download data: BEDGRAPH, TXT
15.

Human exosomal placenta-specific miRNAs modulate expression of target genes in maternal immune cells during pregnancy

(Submitter supplied) We investigated placenta-specific miRNA miR-517a (miR-517a-3p) functions in Jurkat cells. For this purpose, we identified candidate target mRNAs of the placenta-specific miRNAs using DNA microarray analysis. Transfection of Jurkat cells with miR-517a significantly downregulated 123 genes. Among the 123 genes identified, we searched for potential direct targets of miR-517a using the online software MicroCosm Targets. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
2 Samples
Download data: TXT
Series
Accession:
GSE50814
ID:
200050814
16.

Profiling of exosomal miRNAs during maturation of 3T3-L1 adipocytes

(Submitter supplied) We profiled miRNAs in 3T3-L1 adipocyte-secreted exosomes and our microarray analysis revealed that more than 300 exosomal miRNAs were detected during adipocyte differentiation.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL21265
4 Samples
Download data: TXT, XLSX
Series
Accession:
GSE154875
ID:
200154875
17.

Comparative miRNome analysis of bovine sera and exosomes revealing their distinct advantages in studying cattle health

(Submitter supplied) Recently, extra-cellular components, such as serum and exosome, attract more and more attention as biomarker candidates for mammalian health. However, the contribution of different blood components to the signature of respective microRNAs (miRNAs) remains unknown, especially in cattle. In this study we aimed to investigate the miRNAs from bovine sera and exosomes, and to provide insights into their future applications. more...
Organism:
Bos taurus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL15749
8 Samples
Download data: TXT
Series
Accession:
GSE72643
ID:
200072643
18.

The impact of hnRNP-A2B1 on mRNA transport after DNA virus infection

(Submitter supplied) To obtain a wholistic view of hnRNP-A2B1’s role in mRNA transport in response to DNA virus infection, we profiled RNAs from nuclear and cytoplasmic fractions in both wild-type and Hnrnpa2b1–/– macrophages after Herpes simplex virus 1 (HSV-1) infection.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
4 Samples
Download data: CEL
Series
Accession:
GSE129926
ID:
200129926
19.

Expression analysis for detection of mycobacterial transcripts present in exosomes derived from M.tb infected macrophages

(Submitter supplied) Mycobacterial transcripts were identified in exosomes released from M.tb infected RAW264.7 macrophages that were not present in uninfected exosomes suggesting export of mycobacterial RNA via exosomes Mycobacterial RNA was used as positive control and RNA from exosomes released from uninfected macrophages was used as negative control
Organism:
Mycobacterium tuberculosis H37Rv; Mycobacterium tuberculosis
Type:
Expression profiling by array
Platform:
GPL18228
4 Samples
Download data: PAIR
Series
Accession:
GSE54444
ID:
200054444
20.

Host transcripts detected in exosomes derived from M.tb infected murine RAW264.7 macrophages

(Submitter supplied) Investigation to study mRNA transcripts present in exosomes from M.tb infected cells and how they compare to those derived from uninfected cells. Transcripts were also studied in donor macrophages as controls The gene expression study identified unique transcripts as well as differentially expressed transcripts present in exosomes released from infected macrophages
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10572
12 Samples
Download data: PAIR, TXT
Series
Accession:
GSE54419
ID:
200054419
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=9|qty=7|blobid=MCID_6732ea909cf5ff227c0a8250|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center