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Links from GEO DataSets

Items: 20

1.

Expression data from Canton-S and D18 adult flies

(Submitter supplied) Even after decades of living in the same laboratory environment two Drosophila melanogaster strains originating from North America (Canton-S) and Central Russia (D18) demonstrate a few differentially expressed genes some of which may be important for local adaptation (e.g. genes responsible for insecticide resistance). Genes with different level of expression between Canton-S and D18 strains belong to important metabolic pathways, for instance energy metabolism, carbohydrate metabolic process, locomotion, body temperature rhythm regulation and tracheal network architecture. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL1322
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE146725
ID:
200146725
2.

Gene expression variation in African and European populations of Drosophila melanogaster

(Submitter supplied) Background: Differences in levels of gene expression among individuals are an important source of phenotypic variation within populations. Recent microarray studies have revealed that expression variation is abundant in many species, including Drosophila melanogaster. However, previous expression surveys in this species generally focused on a small number of laboratory strains established from derived populations. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL3830
80 Samples
Download data: GPR
Series
Accession:
GSE8843
ID:
200008843
3.

Population and sex differences in Drosophila melanogaster brain gene expression

(Submitter supplied) Background: Changes in gene regulation are thought to be crucial for the adaptation of organisms to their environment. Transcriptome analyses can be used to identify candidate genes for ecological adaptation, but can be complicated by variation in gene expression between tissues, sexes, or individuals. Here we use high-throughput RNA sequencing of a single Drosophila melanogaster tissue to detect brain-specific differences in gene expression between the sexes and between two populations, one from the ancestral species range in sub-Saharan Africa and one from the recently colonized species range in Europe. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
8 Samples
Download data: TXT
Series
Accession:
GSE40907
ID:
200040907
4.

Expression data from middle-aged and old Drosophila females

(Submitter supplied) The mechanisms underlying natural variation in lifespan and ageing rate remain largely unknown. We performed microarray experiment to characterise genome-wide expression patterns of a long-lived, natural variant of Drosophila melanogaster resulting from selection for starvation resistance (SR) and compare it with normal-lived control flies (C).
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL1322
46 Samples
Download data: CEL
Series
Accession:
GSE36582
ID:
200036582
5.

Differential expression in selected adult female Drosophila melanogaster

(Submitter supplied) A study evaluating the effect of stress resistance selection of Drosophila melanogaster. Abstract Here, we report a detailed analysis of changes in gene expression in Drosophila melanogaster selected for multiple eological relevant environmental stress resistance traits. We analyzed females from three biological replicates from seven selection regimes and one control regime using whole genome gene expression arrays. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Dataset:
GDS2830
Platform:
GPL72
24 Samples
Download data: CEL
Series
Accession:
GSE6558
ID:
200006558
6.
Full record GDS2830

Strains resistant to environmental stresses

Analysis of several lines each selected for resistance to a different environmental stress factor. Results provide insight into the molecular and genetic mechanisms that promote adaptation to environmental stresses.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 8 strain sets
Platform:
GPL72
Series:
GSE6558
24 Samples
Download data: CEL
DataSet
Accession:
GDS2830
ID:
2830
7.

Population transcriptomics of Drosophila melanogaster females

(Submitter supplied) To investigate the effect of sex on within- and between-population variation in gene expression, we performed a microarray analysis of adult females from 16 strains of Drosophila melanogaster, including eight strains from the putative ancestral range in sub-Saharan Africa and eight strains from a European population. The results were compared to those of a previous study of adult male gene expression variation among the same strains (GSE8843).
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL3603
56 Samples
Download data: GPR
Series
Accession:
GSE23662
ID:
200023662
8.

Preadult life history variation determines adult transcriptome expression

(Submitter supplied) Investigation of whole genome transcription expression level changes in Drosophila mojavensis wild-type populations (Las Bocas:LB and Punta Prieta:PP). The experiment was designed to investigate preadult life history affects over adult transcriptome expression.
Organism:
Drosophila mojavensis
Type:
Expression profiling by array
Platform:
GPL16433
137 Samples
Download data: PAIR
Series
Accession:
GSE72231
ID:
200072231
9.

Age-related changes of gene expression profiles in Drosophila

(Submitter supplied) An individual’s gene expression profile changes throughout life. This change in gene expression is shaped by differences in physiological needs and functions between the younger and older organism. Here we report a transcriptomic analysis of Drosophila melanogaster using microarrays. We compared the expression profiles of two-day-old female adult flies with those of 45-day-old flies. We identified 1184 genes with pronounced expression level differences between young and old age groups. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL1322
6 Samples
Download data: CEL, TXT
Series
Accession:
GSE187896
ID:
200187896
10.

Regulatory divergence in Drosophila melanogaster and D. simulans: a genome-wide analysis of allele-specific expression

(Submitter supplied) Species-specific regulation of gene expression contributes to the development and maintenance of reproductive isolation and to species differences in ecologically important traits. A better understanding of the evolutionary forces which shape regulatory variation and divergence can be developed by comparing expression differences among species and interspecific hybrids. Once expression differences are identified, the underlying genetics of regulatory variation or divergence can be explored. more...
Organism:
Drosophila melanogaster; Drosophila sp. (in: flies); Drosophila simulans
Type:
Expression profiling by genome tiling array
Platform:
GPL5919
24 Samples
Download data: BAR, CEL
Series
Accession:
GSE17453
ID:
200017453
11.

Bactrocera dorsalis Gene expression

(Submitter supplied) Comprehensive RNA sequencing was performed on a laboratory colony of B. dorsalis with a focus on attempting to capture as many genes in the sequencing from throughout the entire developmental life history. De novo assembly and analysis of the resulting sequence
Organism:
Bactrocera dorsalis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17054
6 Samples
Download data: TXT
Series
Accession:
GSE46310
ID:
200046310
12.

Variation of gene expression associated with colonisation of an anthropized environment: comparison between African and European populations of Drosophila simulans

(Submitter supplied) The comparison of transcriptome profiles among populations is a powerful tool for investigating the role of gene expression change in adaptation to new environments. In this study, we use massively parallel sequencing of 39 cDNAs obtained from large samples of adult males, to compare a population of Drosophila simulans from a natural reserve within its ancestral range (eastern Africa) with a derived population collected in the strongly anthropized Rhone valley (France). more...
Organism:
Drosophila simulans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17484
4 Samples
Download data: TXT
Series
Accession:
GSE49127
ID:
200049127
13.

The sexually antagonistic genes of Drosophila melanogaster

(Submitter supplied) Differences in the selective pressures experienced by males and females are believed to be ubiquitous in dioecious organisms and are expected to result in the evolution of sexually antagonistic alleles, thereby driving the evolution of sexual dimorphism. Negative genetic correlation for fitness between the sexes has been documented, however, the identity, number and location of loci causing this relationship are unknown. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL1322
120 Samples
Download data: CEL
Series
Accession:
GSE17013
ID:
200017013
14.

The Wright Stuff: Reimagining Path Analysis Reveals Novel Components of the Sex Determination Hierarchy in Drosophila Melanogaster

(Submitter supplied) The Drosophila sex determination hierarchy consists of a splicing cascade with sex-specific transcription directing somatic sexual dimorphism. Our understanding of this pathway, and many others, is incomplete. Here we pioneer an approach to expand our knowledge of gene regulatory networks (GRNs) by leveraging natural genetic variation. This approach is generalizable to any natural population, including humans. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11203
9 Samples
Download data: CSV
Series
Accession:
GSE67400
ID:
200067400
15.

Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains

(Submitter supplied) Drosophila melanogaster adult males perform an elaborate courtship ritual to entice females to mate. fruitless (fru), a gene that is one of the key regulators of male courtship behavior, encodes multiple male-specific isoforms (FruM). These isoforms vary in their carboxy-terminal zinc finger domains, which are predicted to facilitate DNA binding. By over-expressing individual FruM isoforms in fru-expressing neurons in either males or females and assaying the global transcriptional response by RNA-sequencing, we show that three FruM isoforms have different regulatory activities that depend on the sex of the fly. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11203
39 Samples
Download data: CSV
Series
Accession:
GSE50515
ID:
200050515
16.

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations

(Submitter supplied) Organisms use endogenous clocks to adapt to the rhythmicity of the environment and to synchronize social activities. Although circadian rhythms have been implicated in multiple aspects of aging, it remains uncertain whether evolutionary selection of circadian cycle gene variants contributes to changes in longevity and aging traits within animal populations. We have sequenced the genomes of Drosophila melanogaster strains with exceptional longevity that were obtained via multiple rounds of selection for reduced senescence from a parental strain. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
72 Samples
Download data: TXT
Series
Accession:
GSE129922
ID:
200129922
17.

Transcriptional profiling of adult Drosophila antennae by high-throughput sequencing

(Submitter supplied) Background Antennae of fruit flies are the major organs responsible for detecting environmental volatiles, e.g., egg-laying substrates. An adult antenna contains many sensilla full of olfactory sensory neurons, where olfactory receptor (Or) genes are expressed. Each sensory neuron only expresses up to three receptors, making it difficult to estimate expression levels by conventional methods. In this study, we applied Illumina RNA sequencing (RNA-seq) to study the expression levels of Or and other genes in fly antennae. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
2 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE99545
ID:
200099545
18.

Expression divergence of chemosensory genes between Drosophila sechellia and its sibling species and its implications for host shift [Dsim JP]

(Submitter supplied) Drosophila simulans relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. simulans host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...
Organism:
Drosophila simulans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13306
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE67862
ID:
200067862
19.

Expression divergence of chemosensory genes between Drosophila sechellia and its sibling species and its implications for host shift [Dsec JP]

(Submitter supplied) Drosophila sechellia relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. sechellia host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...
Organism:
Drosophila sechellia
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20000
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE67861
ID:
200067861
20.

Expression divergence of chemosensory genes between Drosophila sechellia and its sibling species and its implications for host shift [Dsec TW]

(Submitter supplied) Drosophila sechellia relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. sechellia host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...
Organism:
Drosophila sechellia
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20000
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE67587
ID:
200067587
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