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Unusual CNS infection

MedGen UID:
1684837
•Concept ID:
C4759823
•
Disease or Syndrome
Synonyms: Central nervous system infection; central nervous system infection; central nervous system infectious disease; central nervous system infectious disorder; infections, central nervous system; infectious disease of central nervous system
 
HPO: HP:0011450
Monarch Initiative: MONDO:0024619

Definition

A type of infection of the central nervous system that can be regarded as a sign of a pathological susceptibility to infection. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnusual CNS infection

Professional guidelines

PubMed

CLIPPERS and its mimics: evaluation of new criteria for the diagnosis of CLIPPERS.
Taieb G, Mulero P, Psimaras D, van Oosten BW, Seebach JD, Marignier R, Pico F, Rigau V, Ueno Y, Duflos C, Fominykh V, Guiraud V, Lebrun-Frénay C, Camdessanché JP, Kerschen P, Ahle G, Téllez N, Rovira A, Hoang-Xuan K, Pelletier J, Labauge P; in cooperation with the French CLIPPERS group
J Neurol Neurosurg Psychiatry 2019 Sep;90(9):1027-1038. Epub 2019 May 9 doi: 10.1136/jnnp-2018-318957. PMID: 31072955
Treatment for paraneoplastic neuropathies.
Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647
Evaluation and treatment of vasculitis in the critically ill patient.
Merkel PA, Choi HK, Niles JL
Crit Care Clin 2002 Apr;18(2):321-44. doi: 10.1016/s0749-0704(01)00006-9. PMID: 12053837

Recent clinical studies

Etiology

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis.
Gövert F, Abrante L, Becktepe J, Balint B, Ganos C, Hofstadt-van Oy U, Krogias C, Varley J, Irani SR, Paneva S, Titulaer MJ, de Vries JM, Boon AJW, Schreurs MWJ, Joubert B, Honnorat J, Vogrig A, Ariño H, Sabater L, Dalmau J, Scotton S, Jacob S, Melzer N, Bien CG, Geis C, Lewerenz J, Prüss H, Wandinger KP, Deuschl G, Leypoldt F
Brain 2023 Feb 13;146(2):657-667. doi: 10.1093/brain/awac276. PMID: 35875984
Human transmissible spongiform encephalopathies: historic view.
Asher DM, Gregori L
Handb Clin Neurol 2018;153:1-17. doi: 10.1016/B978-0-444-63945-5.00001-5. PMID: 29887130
Infections.
Hunter JV, Goerner L
Handb Clin Neurol 2016;136:1173-98. doi: 10.1016/B978-0-444-53486-6.00061-2. PMID: 27430464
Treatment for paraneoplastic neuropathies.
Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647
Pathogenic flaviviruses.
Gould EA, Solomon T
Lancet 2008 Feb 9;371(9611):500-9. doi: 10.1016/S0140-6736(08)60238-X. PMID: 18262042

Diagnosis

Bacterial Infections of the Central Nervous System.
LaPenna PA, Roos KL
Semin Neurol 2019 Jun;39(3):334-342. Epub 2019 Aug 2 doi: 10.1055/s-0039-1693159. PMID: 31378869
Infectious encephalitis: mimics and chameleons.
Toledano M, Davies NWS
Pract Neurol 2019 Jun;19(3):225-237. Epub 2019 Mar 16 doi: 10.1136/practneurol-2018-002114. PMID: 30878971
Human transmissible spongiform encephalopathies: historic view.
Asher DM, Gregori L
Handb Clin Neurol 2018;153:1-17. doi: 10.1016/B978-0-444-63945-5.00001-5. PMID: 29887130
Sporadic and Infectious Human Prion Diseases.
Will RG, Ironside JW
Cold Spring Harb Perspect Med 2017 Jan 3;7(1) doi: 10.1101/cshperspect.a024364. PMID: 27793965Free PMC Article
The aseptic meningitis syndrome.
Nelsen S, Sealy DP, Schneider EF
Am Fam Physician 1993 Oct;48(5):809-15. PMID: 8213411

Therapy

Diagnosis of extrapulmonary tuberculosis by GeneXpert MTB/RIF Ultra assay.
Dahiya B, Mehta N, Soni A, Mehta PK
Expert Rev Mol Diagn 2023 Jul-Dec;23(7):561-582. Epub 2023 Jun 23 doi: 10.1080/14737159.2023.2223980. PMID: 37318829
Bacterial Infections of the Central Nervous System.
LaPenna PA, Roos KL
Semin Neurol 2019 Jun;39(3):334-342. Epub 2019 Aug 2 doi: 10.1055/s-0039-1693159. PMID: 31378869
Rickettsial meningitis.
Salva I, de Sousa R, Gouveia C
BMJ Case Rep 2014 Mar 10;2014 doi: 10.1136/bcr-2013-203283. PMID: 24614778Free PMC Article
Severe complications of herpes zoster.
Volpi A
Herpes 2007 Sep;14 Suppl 2:35-9. PMID: 17939894
The tetracyclines.
Cunha BA, Comer JB, Jonas M
Med Clin North Am 1982 Jan;66(1):293-302. doi: 10.1016/s0025-7125(16)31461-4. PMID: 7038336

Prognosis

Limbic encephalitis and Post-Acute neuropsychology rehabilitation: A review and case examples.
Perna R, Arenivas A
Appl Neuropsychol Adult 2022 Jul-Aug;29(4):874-880. Epub 2020 Aug 10 doi: 10.1080/23279095.2020.1796669. PMID: 32776797
Lyme Disease in Humans.
Radolf JD, Strle K, Lemieux JE, Strle F
Curr Issues Mol Biol 2021;42:333-384. Epub 2020 Dec 11 doi: 10.21775/cimb.042.333. PMID: 33303701Free PMC Article
Unusual Clinical Presentations Challenging the Early Clinical Diagnosis of Creutzfeldt-Jakob Disease.
Baiardi S, Capellari S, Bartoletti Stella A, Parchi P
J Alzheimers Dis 2018;64(4):1051-1065. doi: 10.3233/JAD-180123. PMID: 30010123
Autoimmune-mediated encephalitis.
Demaerel P, Van Dessel W, Van Paesschen W, Vandenberghe R, Van Laere K, Linn J
Neuroradiology 2011 Nov;53(11):837-51. Epub 2011 Jan 27 doi: 10.1007/s00234-010-0832-0. PMID: 21271243
AIDS-associated lymphoma.
Kaplan LD
Baillieres Clin Haematol 1990 Jan;3(1):139-51. doi: 10.1016/s0950-3536(05)80085-x. PMID: 2182138

Clinical prediction guides

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis.
Gövert F, Abrante L, Becktepe J, Balint B, Ganos C, Hofstadt-van Oy U, Krogias C, Varley J, Irani SR, Paneva S, Titulaer MJ, de Vries JM, Boon AJW, Schreurs MWJ, Joubert B, Honnorat J, Vogrig A, Ariño H, Sabater L, Dalmau J, Scotton S, Jacob S, Melzer N, Bien CG, Geis C, Lewerenz J, Prüss H, Wandinger KP, Deuschl G, Leypoldt F
Brain 2023 Feb 13;146(2):657-667. doi: 10.1093/brain/awac276. PMID: 35875984
Treatment for paraneoplastic neuropathies.
Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647
DOCK8 deficiency.
Su HC, Jing H, Zhang Q
Ann N Y Acad Sci 2011 Dec;1246:26-33. doi: 10.1111/j.1749-6632.2011.06295.x. PMID: 22236427
Autoimmune-mediated encephalitis.
Demaerel P, Van Dessel W, Van Paesschen W, Vandenberghe R, Van Laere K, Linn J
Neuroradiology 2011 Nov;53(11):837-51. Epub 2011 Jan 27 doi: 10.1007/s00234-010-0832-0. PMID: 21271243
AIDS-associated malignant lymphoma.
Levine AM
Med Clin North Am 1992 Jan;76(1):253-68. doi: 10.1016/s0025-7125(16)30379-0. PMID: 1727539

Recent systematic reviews

Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalitis Following COVID-19: Systematic Review and Meta-synthesis.
Manzano GS, McEntire CRS, Martinez-Lage M, Mateen FJ, Hutto SK
Neurol Neuroimmunol Neuroinflamm 2021 Nov;8(6) Epub 2021 Aug 27 doi: 10.1212/NXI.0000000000001080. PMID: 34452974Free PMC Article
Skin nontuberculous mycobacterial infection in systemic lupus erythematosus: an unusual skin infection mimicking lupus vasculitis.
Touma Z, Haddad A, Gladman DD, Uleryk EM, Urowitz MB
Semin Arthritis Rheum 2013 Apr;42(5):498-506. Epub 2013 Jan 16 doi: 10.1016/j.semarthrit.2012.08.002. PMID: 23332736
Treatment for paraneoplastic neuropathies.
Giometto B, Vitaliani R, Lindeck-Pozza E, Grisold W, Vedeler C
Cochrane Database Syst Rev 2012 Dec 12;12:CD007625. doi: 10.1002/14651858.CD007625.pub2. PMID: 23235647

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