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Sporadic Gastric Adenocarcinoma

MedGen UID:
328294
•Concept ID:
C1711192
•
Neoplastic Process

Definition

A primary adenocarcinoma of the stomach in a patient with no family history of gastric cancer or inherited high risk mutations. [from NCI]

Professional guidelines

PubMed

Increased risk of gastric adenocarcinoma after treatment of primary gastric diffuse large B-cell lymphoma.
Inaba K, Kushima R, Murakami N, Kuroda Y, Harada K, Kitaguchi M, Yoshio K, Sekii S, Takahashi K, Morota M, Mayahara H, Ito Y, Sumi M, Uno T, Itami J
BMC Cancer 2013 Oct 26;13:499. doi: 10.1186/1471-2407-13-499. PMID: 24159918Free PMC Article

Recent clinical studies

Etiology

Helicobacter pylori Status May Differentiate Two Distinct Pathways of Gastric Adenocarcinoma Carcinogenesis.
Tobi M, Weinstein D, Kim M, Hatfield J, Sochacki P, Levi E, An T, Hamre M, Tolia V, Fligiel S, Marepally R, Hallman J, Bapat B, Yuan M, McVicker B, Gallinger S
Curr Oncol 2023 Aug 29;30(9):7950-7963. doi: 10.3390/curroncol30090578. PMID: 37754493Free PMC Article
The presence of metastases in regional lymph nodes is associated with tumor size and depth of invasion in sporadic gastric adenocarcinoma.
Cambruzzi E, Azeredo AM, Kronhart A, Foltz KM, Zettler CG, Pêgas KL
Arq Bras Cir Dig 2014 Jan-Mar;27(1):18-21. doi: 10.1590/s0102-67202014000100005. PMID: 24676292Free PMC Article
Increased risk of gastric adenocarcinoma after treatment of primary gastric diffuse large B-cell lymphoma.
Inaba K, Kushima R, Murakami N, Kuroda Y, Harada K, Kitaguchi M, Yoshio K, Sekii S, Takahashi K, Morota M, Mayahara H, Ito Y, Sumi M, Uno T, Itami J
BMC Cancer 2013 Oct 26;13:499. doi: 10.1186/1471-2407-13-499. PMID: 24159918Free PMC Article

Diagnosis

Helicobacter pylori Status May Differentiate Two Distinct Pathways of Gastric Adenocarcinoma Carcinogenesis.
Tobi M, Weinstein D, Kim M, Hatfield J, Sochacki P, Levi E, An T, Hamre M, Tolia V, Fligiel S, Marepally R, Hallman J, Bapat B, Yuan M, McVicker B, Gallinger S
Curr Oncol 2023 Aug 29;30(9):7950-7963. doi: 10.3390/curroncol30090578. PMID: 37754493Free PMC Article

Prognosis

Helicobacter pylori Status May Differentiate Two Distinct Pathways of Gastric Adenocarcinoma Carcinogenesis.
Tobi M, Weinstein D, Kim M, Hatfield J, Sochacki P, Levi E, An T, Hamre M, Tolia V, Fligiel S, Marepally R, Hallman J, Bapat B, Yuan M, McVicker B, Gallinger S
Curr Oncol 2023 Aug 29;30(9):7950-7963. doi: 10.3390/curroncol30090578. PMID: 37754493Free PMC Article
The presence of metastases in regional lymph nodes is associated with tumor size and depth of invasion in sporadic gastric adenocarcinoma.
Cambruzzi E, Azeredo AM, Kronhart A, Foltz KM, Zettler CG, Pêgas KL
Arq Bras Cir Dig 2014 Jan-Mar;27(1):18-21. doi: 10.1590/s0102-67202014000100005. PMID: 24676292Free PMC Article
Increased risk of gastric adenocarcinoma after treatment of primary gastric diffuse large B-cell lymphoma.
Inaba K, Kushima R, Murakami N, Kuroda Y, Harada K, Kitaguchi M, Yoshio K, Sekii S, Takahashi K, Morota M, Mayahara H, Ito Y, Sumi M, Uno T, Itami J
BMC Cancer 2013 Oct 26;13:499. doi: 10.1186/1471-2407-13-499. PMID: 24159918Free PMC Article
Infrequent hMSH2 mutations in sporadic gastric adenocarcinoma with microsatellite instability.
Wu MS, Sheu JC, Shun CT, Lee WJ, Wang JT, Wang TH, Cheng AL, Lin JT
Cancer Lett 1997 Jan 30;112(2):161-6. doi: 10.1016/s0304-3835(96)04565-x. PMID: 9066723

Clinical prediction guides

Increased risk of gastric adenocarcinoma after treatment of primary gastric diffuse large B-cell lymphoma.
Inaba K, Kushima R, Murakami N, Kuroda Y, Harada K, Kitaguchi M, Yoshio K, Sekii S, Takahashi K, Morota M, Mayahara H, Ito Y, Sumi M, Uno T, Itami J
BMC Cancer 2013 Oct 26;13:499. doi: 10.1186/1471-2407-13-499. PMID: 24159918Free PMC Article
Infrequent hMSH2 mutations in sporadic gastric adenocarcinoma with microsatellite instability.
Wu MS, Sheu JC, Shun CT, Lee WJ, Wang JT, Wang TH, Cheng AL, Lin JT
Cancer Lett 1997 Jan 30;112(2):161-6. doi: 10.1016/s0304-3835(96)04565-x. PMID: 9066723

Supplemental Content

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