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Abnormal glomerular capillary morphology

MedGen UID:
927615
•Concept ID:
C4293706
•
Anatomical Abnormality
Synonym: Abnormalities of the glomerular capillary wall
 
HPO: HP:0025006

Definition

A structural anomaly of the capillary blood vessels in the renal glomerulus. [from HPO]

Professional guidelines

PubMed

The spectrum of antibody-mediated renal allograft injury: implications for treatment.
Gloor J, Cosio F, Lager DJ, Stegall MD
Am J Transplant 2008 Jul;8(7):1367-73. doi: 10.1111/j.1600-6143.2008.02262.x. PMID: 18510643

Recent clinical studies

Etiology

Thrombotic microangiopathy associated with monoclonal gammopathy.
Ravindran A, Go RS, Fervenza FC, Sethi S
Kidney Int 2017 Mar;91(3):691-698. Epub 2016 Dec 18 doi: 10.1016/j.kint.2016.09.045. PMID: 27998645
Platelet dysfunction in renal failure.
Boccardo P, Remuzzi G, Galbusera M
Semin Thromb Hemost 2004 Oct;30(5):579-89. doi: 10.1055/s-2004-835678. PMID: 15497100
Ultrastructural changes of glomerular basement membrane in IgA nephritis: relationship to hematuria.
Taguchi T, von Bassewitz DB, Grundmann E, Takebayashi S
Ultrastruct Pathol 1988 Jan-Feb;12(1):17-26. doi: 10.3109/01913128809048473. PMID: 3354074
The glomerular basal lamina in hereditary nephritis.
Yoshikawa N, Cameron AH, White RH
J Pathol 1981 Nov;135(3):199-209. doi: 10.1002/path.1711350305. PMID: 7320813
Crescentic glomerulonephritis: immune vs. nonimmune mechanisms.
Cohen AH, Border WA, Shankel E, Glassock RJ
Am J Nephrol 1981;1(2):78-83. doi: 10.1159/000166494. PMID: 6758575

Diagnosis

Case Report: Endocapillary Glomerulopathy Associated With Large Granular T Lymphocyte Leukemia.
Zhao T, Hu N, Yu X, Su T
Front Immunol 2021;12:810223. Epub 2022 Jan 25 doi: 10.3389/fimmu.2021.810223. PMID: 35145513Free PMC Article
Human parvovirus B19-induced acute glomerulonephritis: a case report.
Shimohata H, Higuchi T, Ogawa Y, Fujita S, Nagai M, Imaizumi M, Maruyama H, Hirayama K, Kobayashi M
Ren Fail 2013;35(1):159-62. Epub 2012 Nov 1 doi: 10.3109/0886022X.2012.736068. PMID: 23113616
Transplant glomerulopathy.
Cosio FG, Gloor JM, Sethi S, Stegall MD
Am J Transplant 2008 Mar;8(3):492-6. doi: 10.1111/j.1600-6143.2007.02104.x. PMID: 18294145
Platelet dysfunction in renal failure.
Boccardo P, Remuzzi G, Galbusera M
Semin Thromb Hemost 2004 Oct;30(5):579-89. doi: 10.1055/s-2004-835678. PMID: 15497100
The loin-pain/haematuria syndrome.
Burden RP, Dathan JR, Etherington MD, Guyer PB, MacIver AG
Lancet 1979 Apr 28;1(8122):897-900. doi: 10.1016/s0140-6736(79)91374-6. PMID: 86667

Therapy

Thrombotic microangiopathy associated with monoclonal gammopathy.
Ravindran A, Go RS, Fervenza FC, Sethi S
Kidney Int 2017 Mar;91(3):691-698. Epub 2016 Dec 18 doi: 10.1016/j.kint.2016.09.045. PMID: 27998645
Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice.
Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T
Am J Physiol Renal Physiol 2010 Mar;298(3):F609-16. Epub 2009 Dec 16 doi: 10.1152/ajprenal.00377.2009. PMID: 20015944
Mechanisms of disease: the hypoxic tubular hypothesis of diabetic nephropathy.
Singh DK, Winocour P, Farrington K
Nat Clin Pract Nephrol 2008 Apr;4(4):216-26. Epub 2008 Feb 12 doi: 10.1038/ncpneph0757. PMID: 18268525
IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children.
Iitaka K, Yamamoto A, Ogawa N, Sekine T, Tamai S, Motoyama O
Clin Exp Nephrol 2003 Dec;7(4):284-9. doi: 10.1007/s10157-003-0253-z. PMID: 14712358
The loin-pain/haematuria syndrome.
Burden RP, Dathan JR, Etherington MD, Guyer PB, MacIver AG
Lancet 1979 Apr 28;1(8122):897-900. doi: 10.1016/s0140-6736(79)91374-6. PMID: 86667

Prognosis

Case Report: Endocapillary Glomerulopathy Associated With Large Granular T Lymphocyte Leukemia.
Zhao T, Hu N, Yu X, Su T
Front Immunol 2021;12:810223. Epub 2022 Jan 25 doi: 10.3389/fimmu.2021.810223. PMID: 35145513Free PMC Article
Clinical significance of IgG deposition in the glomerular mesangial area in patients with IgA nephropathy.
Wada Y, Ogata H, Takeshige Y, Takeshima A, Yoshida N, Yamamoto M, Ito H, Kinugasa E
Clin Exp Nephrol 2013 Feb;17(1):73-82. Epub 2012 Jul 3 doi: 10.1007/s10157-012-0660-0. PMID: 22752397Free PMC Article
Pathophysiology of proteinuria.
D'Amico G, Bazzi C
Kidney Int 2003 Mar;63(3):809-25. doi: 10.1046/j.1523-1755.2003.00840.x. PMID: 12631062
Familial hematuria; clinico-pathological correlations.
Yoshikawa N, White RH, Cameron AH
Clin Nephrol 1982 Apr;17(4):172-82. PMID: 7042145
Crescentic glomerulonephritis: immune vs. nonimmune mechanisms.
Cohen AH, Border WA, Shankel E, Glassock RJ
Am J Nephrol 1981;1(2):78-83. doi: 10.1159/000166494. PMID: 6758575

Clinical prediction guides

Human parvovirus B19-induced acute glomerulonephritis: a case report.
Shimohata H, Higuchi T, Ogawa Y, Fujita S, Nagai M, Imaizumi M, Maruyama H, Hirayama K, Kobayashi M
Ren Fail 2013;35(1):159-62. Epub 2012 Nov 1 doi: 10.3109/0886022X.2012.736068. PMID: 23113616
Pathophysiology of proteinuria.
D'Amico G, Bazzi C
Kidney Int 2003 Mar;63(3):809-25. doi: 10.1046/j.1523-1755.2003.00840.x. PMID: 12631062
Do circulating factors play a role in the pathogenesis of minimal change nephrotic syndrome?
Bakker WW, van Luijk WH
Pediatr Nephrol 1989 Jul;3(3):341-9. doi: 10.1007/BF00858545. PMID: 2702117
Renal lesions in Cockayne syndrome.
Hirooka M, Hirota M, Kamada M
Pediatr Nephrol 1988 Apr;2(2):239-43. doi: 10.1007/BF00862599. PMID: 3153017
Extramembranous glomerulonephritis in childhood: relationship to systemic lupus erythematosus.
Libit SA, Burke B, Michael AF, Vernier RL
J Pediatr 1976 Mar;88(3):394-402. doi: 10.1016/s0022-3476(76)80253-3. PMID: 1245950

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