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Abnormal biliary tract morphology

MedGen UID:
866739
•Concept ID:
C4021086
•
Anatomical Abnormality
Synonym: Anomaly of the biliary tract
 
HPO: HP:0012440

Definition

A structural abnormality of the biliary tree. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Abnormal biliary tract morphology

Professional guidelines

PubMed

Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Fawaz R, Baumann U, Ekong U, Fischler B, Hadzic N, Mack CL, McLin VA, Molleston JP, Neimark E, Ng VL, Karpen SJ
J Pediatr Gastroenterol Nutr 2017 Jan;64(1):154-168. doi: 10.1097/MPG.0000000000001334. PMID: 27429428
Biliary atresia: new concepts of management.
Hays DM, Kimura K
Curr Probl Surg 1981 Sep;18(9):541-608. doi: 10.1016/s0011-3840(81)80016-0. PMID: 7026179
Differential diagnostic approach to clinical problems of malabsorption.
Wilson FA, Dietschy JM
Gastroenterology 1971 Dec;61(6):911-31. PMID: 4108201

Recent clinical studies

Etiology

Gastrointestinal disorders in Down syndrome.
Bermudez BEBV, de Oliveira CM, de Lima Cat MN, Magdalena NIR, Celli A
Am J Med Genet A 2019 Aug;179(8):1426-1431. Epub 2019 Jun 10 doi: 10.1002/ajmg.a.61258. PMID: 31183986
Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Congenital fibrocystic liver diseases.
Drenth JP, Chrispijn M, Bergmann C
Best Pract Res Clin Gastroenterol 2010 Oct;24(5):573-84. doi: 10.1016/j.bpg.2010.08.007. PMID: 20955960
Choledochal cyst.
Gafur MA, Rahman MZ
Mymensingh Med J 2007 Jan;16(1):113-6. doi: 10.3329/mmj.v16i1.264. PMID: 17344793
Biliary cystic disease.
Levy AD, Rohrmann CA Jr
Curr Probl Diagn Radiol 2003 Nov-Dec;32(6):233-63. doi: 10.1016/j.cpradiol.2003.08.002. PMID: 14647122

Diagnosis

Gallstones.
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Congenital fibrocystic liver diseases.
Drenth JP, Chrispijn M, Bergmann C
Best Pract Res Clin Gastroenterol 2010 Oct;24(5):573-84. doi: 10.1016/j.bpg.2010.08.007. PMID: 20955960
Biliary cystic disease.
Levy AD, Rohrmann CA Jr
Curr Probl Diagn Radiol 2003 Nov-Dec;32(6):233-63. doi: 10.1016/j.cpradiol.2003.08.002. PMID: 14647122
Congenital biliary dilatation.
Miyano T, Yamataka A, Li L
Semin Pediatr Surg 2000 Nov;9(4):187-95. doi: 10.1053/spsu.2000.18843. PMID: 11112836
Obstructive biliary tract disease.
White TT
West J Med 1982 Jun;136(6):484-504. PMID: 7051569Free PMC Article

Therapy

History!
Nayak LJ, Sondhi AR, Westerhoff M
Gastroenterology 2021 May;160(6):e5-e6. Epub 2020 Oct 8 doi: 10.1053/j.gastro.2020.09.048. PMID: 33039473
The cholangiocyte primary cilium in health and disease.
Mansini AP, Peixoto E, Thelen KM, Gaspari C, Jin S, Gradilone SA
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1245-1253. Epub 2017 Jun 15 doi: 10.1016/j.bbadis.2017.06.006. PMID: 28625917Free PMC Article
Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Liver transplantation.
Bowers BA, Rotolo FS, McCann RL, Bollinger RR, Meyers WC
Invest Radiol 1985 Nov;20(8):790-5. doi: 10.1097/00004424-198511000-00005. PMID: 3908382
Neonatal nonhemolytic jaundice.
Johnson JD
N Engl J Med 1975 Jan 23;292(4):194-7. doi: 10.1056/NEJM197501232920406. PMID: 803225

Prognosis

Biliary atresia: A comprehensive review.
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Biliary atresia.
Mieli-Vergani G, Vergani D
Semin Immunopathol 2009 Sep;31(3):371-81. Epub 2009 Jun 17 doi: 10.1007/s00281-009-0171-6. PMID: 19533128
Multiseptate gallbladder.
Rivera-Troche EY, Hartwig MG, Vaslef SN
J Gastrointest Surg 2009 Sep;13(9):1741-3. Epub 2009 Apr 8 doi: 10.1007/s11605-009-0880-0. PMID: 19352782
Caroli's disease.
Mercadier M, Chigot JP, Clot JP, Langlois P, Lansiaux P
World J Surg 1984 Feb;8(1):22-9. doi: 10.1007/BF01658359. PMID: 6367232
Obstructive biliary tract disease.
White TT
West J Med 1982 Jun;136(6):484-504. PMID: 7051569Free PMC Article

Clinical prediction guides

Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling.
Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS
Proc Natl Acad Sci U S A 2022 Dec 13;119(50):e2201097119. Epub 2022 Dec 5 doi: 10.1073/pnas.2201097119. PMID: 36469766Free PMC Article
Choledochal cysts: Similarities and differences between Asian and Western countries.
Baison GN, Bonds MM, Helton WS, Kozarek RA
World J Gastroenterol 2019 Jul 14;25(26):3334-3343. doi: 10.3748/wjg.v25.i26.3334. PMID: 31341359Free PMC Article
The cholangiocyte primary cilium in health and disease.
Mansini AP, Peixoto E, Thelen KM, Gaspari C, Jin S, Gradilone SA
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1245-1253. Epub 2017 Jun 15 doi: 10.1016/j.bbadis.2017.06.006. PMID: 28625917Free PMC Article
Liver involvement in Turner syndrome.
Roulot D
Liver Int 2013 Jan;33(1):24-30. Epub 2012 Nov 1 doi: 10.1111/liv.12007. PMID: 23121401
Hepatobiliary pathology.
Lefkowitch JH
Curr Opin Gastroenterol 2005 May;21(3):260-9. doi: 10.1097/01.mog.0000159820.78532.68. PMID: 15818145

Recent systematic reviews

Comprehensive classification of anatomical variants of the main biliary ducts.
Janssen BV, van Laarhoven S, Elshaer M, Cai H, Praseedom R, Wang T, Liau SS
Br J Surg 2021 May 27;108(5):458-462. doi: 10.1093/bjs/znaa147. PMID: 33723607
A systematic review of the anatomical findings of multiple gallbladders.
Darnis B, Mohkam K, Cauchy F, Cazauran JB, Bancel B, Rode A, Ducerf C, Lesurtel M, Mabrut JY
HPB (Oxford) 2018 Nov;20(11):985-991. Epub 2018 Jun 7 doi: 10.1016/j.hpb.2018.04.002. PMID: 29887260
Utility of fluorescent cholangiography during laparoscopic cholecystectomy: A systematic review.
Pesce A, Piccolo G, La Greca G, Puleo S
World J Gastroenterol 2015 Jul 7;21(25):7877-83. doi: 10.3748/wjg.v21.i25.7877. PMID: 26167088Free PMC Article
Routine histological analysis of a macroscopically normal gallbladder--a review of the literature.
Jamal K, Ratansingham K, Siddique M, Nehra D
Int J Surg 2014;12(9):958-62. Epub 2014 Jul 22 doi: 10.1016/j.ijsu.2014.07.010. PMID: 25058481
Torsion of the gallbladder: a systematic review.
Reilly DJ, Kalogeropoulos G, Thiruchelvam D
HPB (Oxford) 2012 Oct;14(10):669-72. Epub 2012 Jul 3 doi: 10.1111/j.1477-2574.2012.00513.x. PMID: 22954002Free PMC Article

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