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Locally Advanced Squamous Cell Carcinoma

MedGen UID:
1651681
Concept ID:
C4727578
Neoplastic Process

Definition

A squamous cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Montagnani F, Fornaro L, Frumento P, Vivaldi C, Falcone A, Fioretto L
Crit Rev Oncol Hematol 2017 Jun;114:24-32. Epub 2017 Mar 23 doi: 10.1016/j.critrevonc.2017.03.024. PMID: 28477744
Zinman LN, Vanni AJ
Urol Clin North Am 2016 Nov;43(4):505-513. doi: 10.1016/j.ucl.2016.06.011. PMID: 27717436
Ang KK
Oncologist 2008 Aug;13(8):899-910. Epub 2008 Aug 13 doi: 10.1634/theoncologist.2007-0157. PMID: 18701764

Recent clinical studies

Etiology

Tao Y, Sun XS, Pointreau Y, Le Tourneau C, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Calderon B, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Damstrup L, Crompton P, Ennaji A, Gollmer K, Nauwelaerts H, Bourhis J
Eur J Cancer 2023 Apr;183:24-37. Epub 2023 Jan 9 doi: 10.1016/j.ejca.2022.12.015. PMID: 36796234
Kiyota N, Tahara M, Mizusawa J, Kodaira T, Fujii H, Yamazaki T, Mitani H, Iwae S, Fujimoto Y, Onozawa Y, Hanai N, Ogawa T, Hara H, Monden N, Shimura E, Minami S, Fujii T, Tanaka K, Homma A, Yoshimoto S, Oridate N, Omori K, Ueda T, Okami K, Ota I, Shiga K, Sugasawa M, Asakage T, Saito Y, Murono S, Nishimura Y, Nakamura K, Hayashi R; Head and Neck Cancer Study Group of the Japan Clinical Oncology Group (JCOG-HNCSG)
J Clin Oncol 2022 Jun 20;40(18):1980-1990. Epub 2022 Mar 1 doi: 10.1200/JCO.21.01293. PMID: 35230884Free PMC Article
Lee NY, Ferris RL, Psyrri A, Haddad RI, Tahara M, Bourhis J, Harrington K, Chang PM, Lin JC, Razaq MA, Teixeira MM, Lövey J, Chamois J, Rueda A, Hu C, Dunn LA, Dvorkin MV, De Beukelaer S, Pavlov D, Thurm H, Cohen E
Lancet Oncol 2021 Apr;22(4):450-462. doi: 10.1016/S1470-2045(20)30737-3. PMID: 33794205
Yang H, Liu H, Chen Y, Zhu C, Fang W, Yu Z, Mao W, Xiang J, Han Y, Chen Z, Yang H, Wang J, Pang Q, Zheng X, Yang H, Li T, Lordick F, D'Journo XB, Cerfolio RJ, Korst RJ, Novoa NM, Swanson SJ, Brunelli A, Ismail M, Fernando HC, Zhang X, Li Q, Wang G, Chen B, Mao T, Kong M, Guo X, Lin T, Liu M, Fu J; AME Thoracic Surgery Collaborative Group
J Clin Oncol 2018 Sep 20;36(27):2796-2803. Epub 2018 Aug 8 doi: 10.1200/JCO.2018.79.1483. PMID: 30089078Free PMC Article
Argiris A, Karamouzis MV, Raben D, Ferris RL
Lancet 2008 May 17;371(9625):1695-709. doi: 10.1016/S0140-6736(08)60728-X. PMID: 18486742Free PMC Article

Diagnosis

Bourhis J, Burtness B, Licitra LF, Nutting C, Schoenfeld JD, Omar M, Bouisset F, Nauwelaerts H, Urfer Y, Zanna C, Cohen EE
Future Oncol 2022 May;18(14):1669-1678. Epub 2022 Feb 17 doi: 10.2217/fon-2021-1634. PMID: 35172587
Kozuki R, Watanabe M, Toihata T, Takahashi K, Otake R, Okamura A, Imamura Y, Mine S
Surg Today 2022 Mar;52(3):377-384. Epub 2021 Jul 30 doi: 10.1007/s00595-021-02348-9. PMID: 34331129
Gadducci A, Aletti GD
Gynecol Oncol 2020 Jul;158(1):208-217. Epub 2020 May 25 doi: 10.1016/j.ygyno.2020.05.021. PMID: 32460996
Alorabi M, Shonka NA, Ganti AK
Crit Rev Oncol Hematol 2016 Mar;99:170-9. Epub 2015 Dec 19 doi: 10.1016/j.critrevonc.2015.12.006. PMID: 26797287
Argiris A, Karamouzis MV, Raben D, Ferris RL
Lancet 2008 May 17;371(9625):1695-709. doi: 10.1016/S0140-6736(08)60728-X. PMID: 18486742Free PMC Article

Therapy

Tao Y, Sun XS, Pointreau Y, Le Tourneau C, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Calderon B, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Damstrup L, Crompton P, Ennaji A, Gollmer K, Nauwelaerts H, Bourhis J
Eur J Cancer 2023 Apr;183:24-37. Epub 2023 Jan 9 doi: 10.1016/j.ejca.2022.12.015. PMID: 36796234
Kiyota N, Tahara M, Mizusawa J, Kodaira T, Fujii H, Yamazaki T, Mitani H, Iwae S, Fujimoto Y, Onozawa Y, Hanai N, Ogawa T, Hara H, Monden N, Shimura E, Minami S, Fujii T, Tanaka K, Homma A, Yoshimoto S, Oridate N, Omori K, Ueda T, Okami K, Ota I, Shiga K, Sugasawa M, Asakage T, Saito Y, Murono S, Nishimura Y, Nakamura K, Hayashi R; Head and Neck Cancer Study Group of the Japan Clinical Oncology Group (JCOG-HNCSG)
J Clin Oncol 2022 Jun 20;40(18):1980-1990. Epub 2022 Mar 1 doi: 10.1200/JCO.21.01293. PMID: 35230884Free PMC Article
Bourhis J, Burtness B, Licitra LF, Nutting C, Schoenfeld JD, Omar M, Bouisset F, Nauwelaerts H, Urfer Y, Zanna C, Cohen EE
Future Oncol 2022 May;18(14):1669-1678. Epub 2022 Feb 17 doi: 10.2217/fon-2021-1634. PMID: 35172587
Lee NY, Ferris RL, Psyrri A, Haddad RI, Tahara M, Bourhis J, Harrington K, Chang PM, Lin JC, Razaq MA, Teixeira MM, Lövey J, Chamois J, Rueda A, Hu C, Dunn LA, Dvorkin MV, De Beukelaer S, Pavlov D, Thurm H, Cohen E
Lancet Oncol 2021 Apr;22(4):450-462. doi: 10.1016/S1470-2045(20)30737-3. PMID: 33794205
Argiris A, Karamouzis MV, Raben D, Ferris RL
Lancet 2008 May 17;371(9625):1695-709. doi: 10.1016/S0140-6736(08)60728-X. PMID: 18486742Free PMC Article

Prognosis

Tao Y, Sun XS, Pointreau Y, Le Tourneau C, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Calderon B, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Damstrup L, Crompton P, Ennaji A, Gollmer K, Nauwelaerts H, Bourhis J
Eur J Cancer 2023 Apr;183:24-37. Epub 2023 Jan 9 doi: 10.1016/j.ejca.2022.12.015. PMID: 36796234
Sun XS, Tao Y, Le Tourneau C, Pointreau Y, Sire C, Kaminsky MC, Coutte A, Alfonsi M, Boisselier P, Martin L, Miroir J, Ramee JF, Delord JP, Clatot F, Rolland F, Villa J, Magne N, Elicin O, Gherga E, Nguyen F, Lafond C, Bera G, Calugaru V, Geoffrois L, Chauffert B, Zubel A, Zanna C, Brienza S, Crompton P, Rouits E, Gollmer K, Szyldergemajn S, Bourhis J
Lancet Oncol 2020 Sep;21(9):1173-1187. Epub 2020 Aug 3 doi: 10.1016/S1470-2045(20)30327-2. PMID: 32758455
Gadducci A, Aletti GD
Gynecol Oncol 2020 Jul;158(1):208-217. Epub 2020 May 25 doi: 10.1016/j.ygyno.2020.05.021. PMID: 32460996
Yang H, Liu H, Chen Y, Zhu C, Fang W, Yu Z, Mao W, Xiang J, Han Y, Chen Z, Yang H, Wang J, Pang Q, Zheng X, Yang H, Li T, Lordick F, D'Journo XB, Cerfolio RJ, Korst RJ, Novoa NM, Swanson SJ, Brunelli A, Ismail M, Fernando HC, Zhang X, Li Q, Wang G, Chen B, Mao T, Kong M, Guo X, Lin T, Liu M, Fu J; AME Thoracic Surgery Collaborative Group
J Clin Oncol 2018 Sep 20;36(27):2796-2803. Epub 2018 Aug 8 doi: 10.1200/JCO.2018.79.1483. PMID: 30089078Free PMC Article
Argiris A, Karamouzis MV, Raben D, Ferris RL
Lancet 2008 May 17;371(9625):1695-709. doi: 10.1016/S0140-6736(08)60728-X. PMID: 18486742Free PMC Article

Clinical prediction guides

Ota Y, Kodaira T, Fujii H, Shimokawa M, Yokota T, Nakashima T, Monden N, Homma A, Ueda S, Akimoto T
Int J Clin Oncol 2022 Nov;27(11):1675-1683. Epub 2022 Aug 24 doi: 10.1007/s10147-022-02228-3. PMID: 36001247
Lee NY, Ferris RL, Psyrri A, Haddad RI, Tahara M, Bourhis J, Harrington K, Chang PM, Lin JC, Razaq MA, Teixeira MM, Lövey J, Chamois J, Rueda A, Hu C, Dunn LA, Dvorkin MV, De Beukelaer S, Pavlov D, Thurm H, Cohen E
Lancet Oncol 2021 Apr;22(4):450-462. doi: 10.1016/S1470-2045(20)30737-3. PMID: 33794205
Zibelman M, Mehra R
Am J Clin Oncol 2016 Aug;39(4):396-406. doi: 10.1097/COC.0000000000000283. PMID: 26967327
Ordu AD, Nieder C, Geinitz H, Kup PG, Deymann LF, Scherer V, Combs SE, Fakhrian K
Strahlenther Onkol 2015 Feb;191(2):153-60. Epub 2014 Nov 18 doi: 10.1007/s00066-014-0779-x. PMID: 25404062
Nashiro T, Yagi C, Hirakawa M, Inamine M, Nagai Y, Sakumoto K, Tamaki W, Ogawa K, Toita T, Aoki Y
Int J Clin Oncol 2008 Aug;13(4):335-9. Epub 2008 Aug 15 doi: 10.1007/s10147-007-0758-7. PMID: 18704634

Recent systematic reviews

Mohamed A, Twardy B, Zordok MA, Ashraf K, Alkhoder A, Schrapp K, Steuer C, Chen Z, Pakkala S, Pillai R, Trad Wadsworth J, Higgins K, Beitler JJ, Ramalingam SS, Owonikoko TK, Khuri FR, Shin DM, Behera M, Saba NF
Head Neck 2019 May;41(5):1490-1498. Epub 2019 Mar 5 doi: 10.1002/hed.25379. PMID: 30835900
Iocca O, Farcomeni A, Di Rocco A, Di Maio P, Golusinski P, Pardiñas López S, Savo A, Pellini R, Spriano G
Oral Oncol 2018 May;80:40-51. Epub 2018 Mar 27 doi: 10.1016/j.oraloncology.2018.03.001. PMID: 29706187
Jerzak KJ, Delos Santos K, Saluja R, Lien K, Lee J, Chan KKW
Oral Oncol 2017 Aug;71:1-10. Epub 2017 Jun 3 doi: 10.1016/j.oraloncology.2017.05.011. PMID: 28688674
Szturz P, Wouters K, Kiyota N, Tahara M, Prabhash K, Noronha V, Castro A, Licitra L, Adelstein D, Vermorken JB
Oncologist 2017 Sep;22(9):1056-1066. Epub 2017 May 22 doi: 10.1634/theoncologist.2017-0015. PMID: 28533474Free PMC Article
Petrelli F, Coinu A, Riboldi V, Borgonovo K, Ghilardi M, Cabiddu M, Lonati V, Sarti E, Barni S
Oral Oncol 2014 Nov;50(11):1041-8. Epub 2014 Aug 28 doi: 10.1016/j.oraloncology.2014.08.005. PMID: 25176576

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