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Oropharynx cancer

MedGen UID:
57783
Concept ID:
C0153382
Neoplastic Process
Synonym: Malignant tumor of oropharynx
SNOMED CT: Cancer of oropharynx (363392002); CA - Cancer of oropharynx (363392002); Malignant tumor of mesopharynx (363392002); Malignant tumor of oropharynx (363392002)
 
Monarch Initiative: MONDO:0004608

Definition

A primary or metastatic malignant neoplasm that affects the oropharynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOropharynx cancer

Professional guidelines

PubMed

Wahle B, Zevallos J
Otolaryngol Clin North Am 2020 Dec;53(6):981-994. Epub 2020 Sep 8 doi: 10.1016/j.otc.2020.07.009. PMID: 32917423Free PMC Article
Koyfman SA, Ismaila N, Crook D, D'Cruz A, Rodriguez CP, Sher DJ, Silbermins D, Sturgis EM, Tsue TT, Weiss J, Yom SS, Holsinger FC
J Clin Oncol 2019 Jul 10;37(20):1753-1774. Epub 2019 Feb 27 doi: 10.1200/JCO.18.01921. PMID: 30811281Free PMC Article
Chau NG, Rabinowits G, Haddad RI
Curr Treat Options Oncol 2014 Dec;15(4):595-610. doi: 10.1007/s11864-014-0309-1. PMID: 25240410

Recent clinical studies

Etiology

Margalit DN, Salz T, Venchiarutti R, Milley K, McNamara M, Chima S, Wong J, Druce P, Nekhlyudov L
Head Neck 2022 Nov;44(11):2579-2599. Epub 2022 Jul 18 doi: 10.1002/hed.27142. PMID: 35848095Free PMC Article
Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Rettig EM, Sethi RKV
Hematol Oncol Clin North Am 2021 Oct;35(5):913-931. Epub 2021 Jul 7 doi: 10.1016/j.hoc.2021.05.004. PMID: 34244016
Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM
J Clin Oncol 2019 Dec 1;37(34):3256-3265. Epub 2019 Oct 16 doi: 10.1200/JCO.19.01507. PMID: 31618127Free PMC Article
Taberna M, Mena M, Pavón MA, Alemany L, Gillison ML, Mesía R
Ann Oncol 2017 Oct 1;28(10):2386-2398. doi: 10.1093/annonc/mdx304. PMID: 28633362

Diagnosis

Caudell JJ, Gillison ML, Maghami E, Spencer S, Pfister DG, Adkins D, Birkeland AC, Brizel DM, Busse PM, Cmelak AJ, Colevas AD, Eisele DW, Galloway T, Geiger JL, Haddad RI, Hicks WL, Hitchcock YJ, Jimeno A, Leizman D, Mell LK, Mittal BB, Pinto HA, Rocco JW, Rodriguez CP, Savvides PS, Schwartz D, Shah JP, Sher D, St John M, Weber RS, Weinstein G, Worden F, Yang Bruce J, Yom SS, Zhen W, Burns JL, Darlow SD
J Natl Compr Canc Netw 2022 Mar;20(3):224-234. doi: 10.6004/jnccn.2022.0016. PMID: 35276673
Rettig EM, Sethi RKV
Hematol Oncol Clin North Am 2021 Oct;35(5):913-931. Epub 2021 Jul 7 doi: 10.1016/j.hoc.2021.05.004. PMID: 34244016
Razanamahery J, Caubet M, Gassian N, Echalier C, Soumagne T
Cancer Radiother 2021 Feb;25(1):51-54. Epub 2020 Dec 26 doi: 10.1016/j.canrad.2020.06.025. PMID: 33376045
Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM
J Clin Oncol 2019 Dec 1;37(34):3256-3265. Epub 2019 Oct 16 doi: 10.1200/JCO.19.01507. PMID: 31618127Free PMC Article
Taberna M, Mena M, Pavón MA, Alemany L, Gillison ML, Mesía R
Ann Oncol 2017 Oct 1;28(10):2386-2398. doi: 10.1093/annonc/mdx304. PMID: 28633362

Therapy

Margalit DN, Salz T, Venchiarutti R, Milley K, McNamara M, Chima S, Wong J, Druce P, Nekhlyudov L
Head Neck 2022 Nov;44(11):2579-2599. Epub 2022 Jul 18 doi: 10.1002/hed.27142. PMID: 35848095Free PMC Article
Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
McAllister SD, Abood ME, Califano J, Guzmán M
J Natl Cancer Inst Monogr 2021 Nov 28;2021(58):99-106. doi: 10.1093/jncimonographs/lgab008. PMID: 34850900
Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM
J Clin Oncol 2019 Dec 1;37(34):3256-3265. Epub 2019 Oct 16 doi: 10.1200/JCO.19.01507. PMID: 31618127Free PMC Article
Koyfman SA, Ismaila N, Crook D, D'Cruz A, Rodriguez CP, Sher DJ, Silbermins D, Sturgis EM, Tsue TT, Weiss J, Yom SS, Holsinger FC
J Clin Oncol 2019 Jul 10;37(20):1753-1774. Epub 2019 Feb 27 doi: 10.1200/JCO.18.01921. PMID: 30811281Free PMC Article

Prognosis

Ramos LF, Sobrinho AR, Ribeiro LN, Martins-de-Barros AV, Maurício HA, Ferreira SJ, Carvalho MD
Med Oral Patol Oral Cir Bucal 2022 Jul 1;27(4):e392-e396. doi: 10.4317/medoral.25334. PMID: 35368007Free PMC Article
Zakeri K, Dunn L, Lee N
J Surg Oncol 2021 Nov;124(6):962-966. Epub 2021 Sep 30 doi: 10.1002/jso.26696. PMID: 34595766Free PMC Article
Rettig EM, Sethi RKV
Hematol Oncol Clin North Am 2021 Oct;35(5):913-931. Epub 2021 Jul 7 doi: 10.1016/j.hoc.2021.05.004. PMID: 34244016
Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM
J Clin Oncol 2019 Dec 1;37(34):3256-3265. Epub 2019 Oct 16 doi: 10.1200/JCO.19.01507. PMID: 31618127Free PMC Article
Shinn EH, Valentine A, Jethanandani A, Basen-Engquist K, Fellman B, Urbauer D, Atkinson E, Yusuf SW, Lenihan D, Woods ML, Kies MS, Sood AK, Carmack C, Morrison WH, Gillenwater A, Sturgis EM, Garden AS
Psychosom Med 2016 Jan;78(1):38-48. doi: 10.1097/PSY.0000000000000256. PMID: 26632757Free PMC Article

Clinical prediction guides

Ferris RL, Flamand Y, Weinstein GS, Li S, Quon H, Mehra R, Garcia JJ, Chung CH, Gillison ML, Duvvuri U, O'Malley BW Jr, Ozer E, Thomas GR, Koch WM, Gross ND, Bell RB, Saba NF, Lango M, Méndez E, Burtness B
J Clin Oncol 2022 Jan 10;40(2):138-149. Epub 2021 Oct 26 doi: 10.1200/JCO.21.01752. PMID: 34699271Free PMC Article
Zakeri K, Dunn L, Lee N
J Surg Oncol 2021 Nov;124(6):962-966. Epub 2021 Sep 30 doi: 10.1002/jso.26696. PMID: 34595766Free PMC Article
Koyfman SA, Ismaila N, Crook D, D'Cruz A, Rodriguez CP, Sher DJ, Silbermins D, Sturgis EM, Tsue TT, Weiss J, Yom SS, Holsinger FC
J Clin Oncol 2019 Jul 10;37(20):1753-1774. Epub 2019 Feb 27 doi: 10.1200/JCO.18.01921. PMID: 30811281Free PMC Article
Hussein AA, Helder MN, de Visscher JG, Leemans CR, Braakhuis BJ, de Vet HCW, Forouzanfar T
Eur J Cancer 2017 Sep;82:115-127. Epub 2017 Jun 24 doi: 10.1016/j.ejca.2017.05.026. PMID: 28654785
Taberna M, Mena M, Pavón MA, Alemany L, Gillison ML, Mesía R
Ann Oncol 2017 Oct 1;28(10):2386-2398. doi: 10.1093/annonc/mdx304. PMID: 28633362

Recent systematic reviews

Margalit DN, Salz T, Venchiarutti R, Milley K, McNamara M, Chima S, Wong J, Druce P, Nekhlyudov L
Head Neck 2022 Nov;44(11):2579-2599. Epub 2022 Jul 18 doi: 10.1002/hed.27142. PMID: 35848095Free PMC Article
Iorio GC, Arcadipane F, Martini S, Ricardi U, Franco P
Crit Rev Oncol Hematol 2021 Apr;160:103243. Epub 2021 Jan 29 doi: 10.1016/j.critrevonc.2021.103243. PMID: 33516806
Hussein AA, Helder MN, de Visscher JG, Leemans CR, Braakhuis BJ, de Vet HCW, Forouzanfar T
Eur J Cancer 2017 Sep;82:115-127. Epub 2017 Jun 24 doi: 10.1016/j.ejca.2017.05.026. PMID: 28654785
Winquist E, Agbassi C, Meyers BM, Yoo J, Chan KKW; Head and Neck Disease Site Group
J Otolaryngol Head Neck Surg 2017 Apr 4;46(1):29. doi: 10.1186/s40463-017-0199-x. PMID: 28376866Free PMC Article
de Almeida JR, Byrd JK, Wu R, Stucken CL, Duvvuri U, Goldstein DP, Miles BA, Teng MS, Gupta V, Genden EM
Laryngoscope 2014 Sep;124(9):2096-102. Epub 2014 May 27 doi: 10.1002/lary.24712. PMID: 24729006

Supplemental Content

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