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Links from GEO DataSets

Items: 20

1.

Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans

(Submitter supplied) Abstract: Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CUG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence properties of C. parapsilosis, a pathogen particularly associated with infections of premature neonates. We describe here the construction of >200 C. parapsilosis strains carrying double allele deletions of transcription factors, protein kinases and species-specific genes. more...
Organism:
Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18663
24 Samples
Download data: TXT
Series
Accession:
GSE57451
ID:
200057451
2.

Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida parapsilosis; Candida albicans
Type:
Expression profiling by array
Platforms:
GPL13192 GPL10903
18 Samples
Download data: GPR
Series
Accession:
GSE33490
ID:
200033490
3.

Transcriptional profile of Candida parapsilosis CLIB214 culture in low iron conditions

(Submitter supplied) Whole genome microarrays were used to generate the transcriptional profile of Candida parapsilosis in low iron conditions
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
7 Samples
Download data: GPR
Series
Accession:
GSE33462
ID:
200033462
4.

Transcriptional profile of Candida parapsilosis bcr1 knockout.

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida parapsilosis bcr1 knockout to wild type cells.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
7 Samples
Download data: GPR
Series
Accession:
GSE33461
ID:
200033461
5.

Transcriptional profile of Candida albicans bcr1 knockout.

(Submitter supplied) Whole genome microarrays were used to compare the transcriptional profile of Candida albicans bcr1 knockout to wild type cells.
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL10903
4 Samples
Download data: GPR
Series
Accession:
GSE33460
ID:
200033460
6.

Pheromone-induced biofilm arrays in the planktonic and pheromone-induced biofilm growth conditions

(Submitter supplied) Candida albicans can stochastically switch between two phenotypes, white and opaque. Opaque cells are the sexually competent form of C. albicans and therefore undergo efficient polarized growth and mating in the presence of pheromone. In contrast, white cells cannot mate, but are induced - under a specialized set of conditions - to form biofilms in response to pheromone. In this work, we compare the genetic regulation of such "pheromone-stimulated" biofilms with that of "conventional" C. more...
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL16385
17 Samples
Download data: GPR
Series
Accession:
GSE44449
ID:
200044449
7.

Transcriptional responses of primary murine macrophages to four Candida species

(Submitter supplied) Candidiasis is an infection caused by yeasts of the genus Candida that ranges in severity from debilitating mucosal infections to disseminated disease with high mortality rates. C. albicans is the most common cause of infection, but non-albicans species collectively represent a significant disease burden. Disseminated disease rarely affects immunocompetent individuals, largely due to the action of innate immune cells, including macrophages, in controlling infection. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
21 Samples
Download data: TXT
Series
Accession:
GSE152700
ID:
200152700
8.

Comparative transcriptomic analysis of the response of CUG-clade Candida species to phagocytosis

(Submitter supplied) Pathogenic Candida fungi are a leading cause of opportunistic, hospital-associated bloodstream infections with high mortality rates, typically in immunocompromised patients. Several species, including C. albicans, the most prevalent cause of infection, belong to the monophyletic CUG clade of yeasts. Much is known about the interaction of C. albicans with innate immune cells, which are crucial for controlling infection. more...
Organism:
Candida albicans; Lodderomyces elongisporus; Candida parapsilosis; Clavispora lusitaniae; Candida tropicalis; Mus musculus; Candida dubliniensis
Type:
Expression profiling by high throughput sequencing
12 related Platforms
24 Samples
Download data: TXT
Series
Accession:
GSE151288
ID:
200151288
9.

Filamentation is Associated with Reduced Pathogenicity of Multiple Non-albicans Candida Species

(Submitter supplied) Candidiasis affects a wide variety of immunocompromised individuals, including HIV/AIDS patients and cancer patients on chemotherapy. Candida albicans, a major human fungal pathogen, accounts for about 50% of all cases, while the remainder are caused by the less pathogenic non-albicans Candida species (NACS). These species are believed to be less pathogenic, in part, because they do not filament as readily or robustly as C. more...
Organism:
Candida parapsilosis; Candida tropicalis
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21876 GPL18663
16 Samples
Download data: TXT
Series
Accession:
GSE134321
ID:
200134321
10.

Transcriptional landscape of the pathogenic yeast Candida parapsilosis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida parapsilosis
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL13192 GPL14718
34 Samples
Download data: GPR, SAM
Series
Accession:
GSE32716
ID:
200032716
11.

Transcriptional landscape of Candida parapsilosis

(Submitter supplied) We used next generation sequencing (RNA-seq) to determine the transcriptional profile of C. parapsilosis growing in several conditions including different media, temperatures and oxygen concentrations.
Organism:
Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14718
26 Samples
Download data: SAM
Series
Accession:
GSE32714
ID:
200032714
12.

Transcriptional profile of Candida parapsilosis CLIB214 versus UPC2 delete, both at 1% oxygen (hypoxia)

(Submitter supplied) Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis UPC2 delete in hypoxia.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
4 Samples
Download data: GPR
Series
Accession:
GSE32713
ID:
200032713
13.

Transcriptional profile of Candida parapsilosis CLIB214 21% Oxygen (normoxia) versus at 1% oxygen (hypoxia).

(Submitter supplied) Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis in hypoxic condition.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL13192
4 Samples
Download data: GPR
Series
Accession:
GSE32712
ID:
200032712
14.

Hypoxia and biofilms in Candida parapsilosis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platforms:
GPL4574 GPL7693
10 Samples
Download data: GPR
Series
Accession:
GSE13832
ID:
200013832
15.

Transcriptional response of Candida parapsilosis in low oxygen (hypoxic) conditions in SD media

(Submitter supplied) Whole genome microarray was used to compare the transcriptional profile of C. parapsilosis growing in normoxic (21% oxygen) and hypoxic (1% oxygen) conditions.
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL7693
6 Samples
Download data: GPR
Series
Accession:
GSE13722
ID:
200013722
16.

Transcriptional profile of Candida parapsilosis in SD media

(Submitter supplied) Partial genome microarray and plankton cells
Organism:
Candida parapsilosis
Type:
Expression profiling by array
Platform:
GPL4574
4 Samples
Download data: GPR
Series
Accession:
GSE13717
ID:
200013717
17.

ChIP-Seq analysis of Candida albicans Sfl1p and Sfl2p

(Submitter supplied) Sfl1p and Sfl2p are two homologous heat shock factor-type transcriptional regulators that antagonistically control morphogenesis in Candida albicans, while being required for full pathogenesis and virulence. To understand how Sfl1p and Sfl2p exert their function, we combined genome-wide location and expression analyses to reveal their transcriptional targets in vivo together with the associated changes of the C. more...
Organism:
Candida albicans
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL15645
8 Samples
Download data: WIG
Series
Accession:
GSE42886
ID:
200042886
18.

Homo sapiens whole blood infected with Candida spp.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Nakaseomyces glabratus; Homo sapiens; Candida tropicalis; Candida albicans; Candida parapsilosis
Type:
Expression profiling by high throughput sequencing
5 related Platforms
75 Samples
Download data
Series
Accession:
GSE114180
ID:
200114180
19.

Homo sapiens whole blood.

(Submitter supplied) RNA extracted at 240min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
3 Samples
Download data: CSV
20.

Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida tropicalis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida tropicalis gene expression.
Organism:
Candida tropicalis; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24977
18 Samples
Download data: CSV
Series
Accession:
GSE114178
ID:
200114178
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