|
| Status |
Public on Jan 20, 2016 |
| Title |
miRNA from leukemia cells |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human betaherpesvirus 5; Murid betaherpesvirus 1; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
In primary leukemia cells there is a significant over-representation of positively correlated microRNA and mRNA expression (see GSE66708) for genes containing sequences favoring microRNA-duplex DNA triplex formation, suggesting this as a mechanism by which microRNA may enhance gene transcription.
|
| |
|
| Overall design |
RNA was extracted from fresh leukemic blasts and hybridized to a panel of miRNA probes.
|
| |
|
| Contributor(s) |
William E, Steve P, Erik B |
| Citation(s) |
26844769 |
| |
| Submission date |
Jan 13, 2016 |
| Last update date |
May 10, 2016 |
| Contact name |
William Evans |
| E-mail(s) |
william.evans@stjude.org
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Pharmaceutical Sciences
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL7722 |
miRCURY LNA microRNA Array, v.10.0 - hsa, mmu & rno |
| GPL11434 |
miRCURY LNA microRNA Array, 6th generation - hsa, mmu & rno |
|
| Samples (260)
|
|
| Relations |
| BioProject |
PRJNA308753 |
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