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Clear cell carcinoma of kidney(RCC)

MedGen UID:
76018
•Concept ID:
C0279702
•
Neoplastic Process
Synonyms: Clear cell RCC; Clear cell renal carcinoma; Clear cell renal cell carcinoma; Clear-cell metastatic renal cell carcinoma (subtype); Cystic-multilocular variant; Renal cell carcinoma, clear cell, somatic
SNOMED CT: Clear cell renal cell carcinoma (254915003); Clear cell carcinoma of kidney (254915003); Clear cell renal cell carcinoma (1187306007); Grawitz tumor (41607009); Hypernephroma (41607009)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
HPO: HP:0006770
Monarch Initiative: MONDO:0005005
OMIM®: 142410; 144700; 606083
Orphanet: ORPHA319276

Definition

A subtype of renal cell carcinoma thought to originate from mature renal tubular cells in the proximal tubule of the nehpron. [from HPO]

Conditions with this feature

Birt-Hogg-Dube syndrome 2
MedGen UID:
1841312
•Concept ID:
C5830676
•
Disease or Syndrome
Birt-Hogg-Dube syndrome-2 (BHD2) is characterized by lipomatosis and fibrofolliculomas as well as renal cell carcinoma and other cancers (van de Beek et al., 2023). For a general phenotypic description and a discussion of genetic heterogeneity of BHD, see BHD1 (135150).
See: Condition Record
Birt-Hogg-Dube syndrome 2

Professional guidelines

PubMed

Treatment of kidney clear cell carcinoma, lung adenocarcinoma and glioblastoma cell lines with hydrogels made of DNA nanostars.
Leo M, Lattuada E, Caprara D, Salvatori L, Vecchione A, Sciortino F, Filetici P, Stoppacciaro A
Biomater Sci 2022 Mar 2;10(5):1304-1316. doi: 10.1039/d1bm01643a. PMID: 35084413

Recent clinical studies

Diagnosis

CT diagnosis for metastasis of clear cell renal cell carcinoma to the pancreas: Three case reports.
Yu Q, Kan F, Ma Z, Wang T, Lin G, Chen B, Zhao W
Medicine (Baltimore) 2018 Nov;97(46):e13200. doi: 10.1097/MD.0000000000013200. PMID: 30431594Free PMC Article
Clear cell changes in mucinous tubular and spindle cell carcinoma: cytoplasmic pallor/clearing within tubules, vacuoles or hybrid conventional clear cell carcinoma of kidney?
Cao W, Huang B, Fei X, Huang X, Dai J, Zhou W, Xu Z, Su H, Cheng K, Sun F
Int J Clin Exp Pathol 2014;7(7):4350-8. Epub 2014 Jun 15 PMID: 25120820Free PMC Article
Cytohistological study of clear cell carcinoma of kidney with special reference to nuclear grading and tumor size.
Mondal SK
Diagn Cytopathol 2012 Dec;40(12):1083-7. Epub 2011 May 11 doi: 10.1002/dc.21740. PMID: 21563327

Prognosis

Clear cell changes in mucinous tubular and spindle cell carcinoma: cytoplasmic pallor/clearing within tubules, vacuoles or hybrid conventional clear cell carcinoma of kidney?
Cao W, Huang B, Fei X, Huang X, Dai J, Zhou W, Xu Z, Su H, Cheng K, Sun F
Int J Clin Exp Pathol 2014;7(7):4350-8. Epub 2014 Jun 15 PMID: 25120820Free PMC Article
Cytohistological study of clear cell carcinoma of kidney with special reference to nuclear grading and tumor size.
Mondal SK
Diagn Cytopathol 2012 Dec;40(12):1083-7. Epub 2011 May 11 doi: 10.1002/dc.21740. PMID: 21563327

Clinical prediction guides

Cytohistological study of clear cell carcinoma of kidney with special reference to nuclear grading and tumor size.
Mondal SK
Diagn Cytopathol 2012 Dec;40(12):1083-7. Epub 2011 May 11 doi: 10.1002/dc.21740. PMID: 21563327

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

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    Reviews

    Related information

    • ClinVar
      Related medical variations
    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

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