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Series GSE31595

Query DataSets for GSE31595

Status

Public on Sep 01, 2011

Title

Gene Expression Profiles in Stage II and III Colon Cancer. Application of a 128-gene signature

Organism

Homo sapiens

Experiment type

Expression profiling by array
Third-party reanalysis

Summary

Purpose: A 128-gene signature has been proposed to predict poor outcomes in patients with stage II and III colorectal cancer. In the present study we aimed to validate this previously published 128-gene signature on external and independent data from patients with stage II and III colon cancer.

Overall design

Tumor samples were obtained from 37 patients with stage II and III colon cancer, who underwent colon resection at the Department of Surgery, Roskilde Hospital, Denmark and the Department of Surgery, Bispebjerg Hospital, Denmark between 2001 and 2008. Purified tumor RNA was reverse-transcribed, labelled and hybridized to Affymetrix Human Genome U133 Plus 2.0 GeneChip Array (Affymetrix, Santa Clara, USA) according to the manufacturers instructions and scanned at the RH Microarray Center, Rigshospitalet, University of Copenhagen.

Contributor(s)

Thorsteinsson M, Kirkeby LT, Lund LR, Sørensen LT, Gerds TA, Jess P, Olsen J

Citation(s)

22710688

Submission date

Aug 23, 2011

Last update date

Mar 25, 2019

Contact name

Morten Thorsteinsson

E-mail(s)

moth@regionsjaelland.dk

Phone

+45 61276425

Fax

+45 47323009

Organization name

Roskilde Hospital, University of Copenhagen

Department

Department of Surgery

Street address

Koegevej 7-13

City

Roskilde

ZIP/Postal code

4000

Country

Denmark

Platforms (1)

GPL570

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

Samples (37)

More...

GSM782671	Colon_R06_2361
GSM782674	Colon_R09_2362
GSM784850	Colon_R14_2363

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BioProject

Download family	Format
SOFT formatted family file(s)	SOFT
MINiML formatted family file(s)	MINiML
Series Matrix File(s)	TXT

Supplementary file	Size	Download	File type/resource
GSE31595_RAW.tar	165.8 Mb	(http)(custom)	TAR (of CEL)
GSE31595_complete_dataset.txt.gz	46.7 Mb	(ftp)(http)	TXT
GSE31595_readme.txt	4.4 Kb	(ftp)(http)	TXT
Processed data included within Sample table