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Benign Squamous Cell Neoplasm

MedGen UID:
141634
Concept ID:
C0474800
Neoplastic Process
Synonyms: Benign Epidermoid Cell Neoplasm; Benign Epidermoid Cell Tumor; Benign squamous cell tumor; Benign Squamous Cell Tumor
SNOMED CT: Benign squamous cell tumor (252994001)

Definition

A non-metastasizing neoplasm composed of squamous cells. The neoplastic cells do not display malignant features. [from NCI]

Professional guidelines

PubMed

Kant R, Davis A, Verma V
Am Fam Physician 2020 Sep 1;102(5):298-304. PMID: 32866364
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM, Dinauer CA, Hamilton J, Hay ID, Luster M, Parisi MT, Rachmiel M, Thompson GB, Yamashita S; American Thyroid Association Guidelines Task Force
Thyroid 2015 Jul;25(7):716-59. doi: 10.1089/thy.2014.0460. PMID: 25900731Free PMC Article

Recent clinical studies

Etiology

Van Acker SI, Van den Bogerd B, Haagdorens M, Siozopoulou V, Ní Dhubhghaill S, Pintelon I, Koppen C
Cells 2021 Jun 22;10(7) doi: 10.3390/cells10071567. PMID: 34206333Free PMC Article
Corchado-Cobos R, García-Sancha N, González-Sarmiento R, Pérez-Losada J, Cañueto J
Int J Mol Sci 2020 Apr 22;21(8) doi: 10.3390/ijms21082956. PMID: 32331425Free PMC Article
Doğan S, Vural A, Kahriman G, İmamoğlu H, Abdülrezzak Ü, Öztürk M
Braz J Otorhinolaryngol 2020 Jul-Aug;86(4):468-482. Epub 2019 Mar 16 doi: 10.1016/j.bjorl.2019.02.003. PMID: 30956151Free PMC Article
Sinclair R, Meah N, Arasu A
Aust J Gen Pract 2019 Sep;48(9):614-619. doi: 10.31128/AJGP-03-19-4887. PMID: 31476828
Parekh V, Seykora JT
Clin Lab Med 2017 Sep;37(3):503-525. doi: 10.1016/j.cll.2017.06.003. PMID: 28802498

Diagnosis

Ye Q, Jia M, Deng LJ, Fang S
J Cutan Med Surg 2023 Mar-Apr;27(2):150-156. Epub 2023 Feb 14 doi: 10.1177/12034754231155895. PMID: 36789508
Savant D, Zhang Q, Yang Z
Arch Pathol Lab Med 2021 May 1;145(5):554-561. doi: 10.5858/arpa.2020-0058-RA. PMID: 32271610
Ettinger KS, Yetzer JG
Oral Maxillofac Surg Clin North Am 2017 Nov;29(4):487-501. doi: 10.1016/j.coms.2017.07.004. PMID: 28987229
Parekh V, Seykora JT
Clin Lab Med 2017 Sep;37(3):503-525. doi: 10.1016/j.cll.2017.06.003. PMID: 28802498
Mandrell JC, Santa Cruz D
Semin Diagn Pathol 2009 Aug;26(3):150-63. doi: 10.1053/j.semdp.2009.09.003. PMID: 20043514

Therapy

Parekh V, Seykora JT
Clin Lab Med 2017 Sep;37(3):503-525. doi: 10.1016/j.cll.2017.06.003. PMID: 28802498
Gleich T, Chiticariu E, Huber M, Hohl D
Exp Dermatol 2016 Feb;25(2):85-91. Epub 2015 Dec 4 doi: 10.1111/exd.12880. PMID: 26476131
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM
Thyroid 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110. PMID: 19860577
Lin J, Iannettoni MD
Surg Clin North Am 2005 Jun;85(3):593-610. doi: 10.1016/j.suc.2005.01.009. PMID: 15927654
Mathisen DJ
Chest Surg Clin N Am 1996 Nov;6(4):875-98. PMID: 8934015

Prognosis

Thapa R, Gurung P, Hirachand S, Shrestha SB
JNMA J Nepal Med Assoc 2018 Nov-Dec;56(214):953-957. doi: 10.31729/jnma.3988. PMID: 31065142Free PMC Article
Rodrigues IA Jr, Gresta LT, Cruz RC, Carvalho GG, Moreira MH
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):209-11. doi: 10.1590/abd1806-4841.20132488. PMID: 24346922Free PMC Article
Rezaei MK, Nolan NJ, Schwartz AM
Semin Respir Crit Care Med 2013 Dec;34(6):770-86. Epub 2013 Nov 20 doi: 10.1055/s-0033-1358558. PMID: 24258567
Lin J, Iannettoni MD
Surg Clin North Am 2005 Jun;85(3):593-610. doi: 10.1016/j.suc.2005.01.009. PMID: 15927654
Kristopaitis T, Thomas C, Petruzzelli GJ, Lee JM
Arch Pathol Lab Med 2000 Sep;124(9):1356-60. doi: 10.5858/2000-124-1356-MC. PMID: 10975938

Clinical prediction guides

Thapa R, Gurung P, Hirachand S, Shrestha SB
JNMA J Nepal Med Assoc 2018 Nov-Dec;56(214):953-957. doi: 10.31729/jnma.3988. PMID: 31065142Free PMC Article
Bhatt N, Gupta N, Soni N, Hooda K, Sapire JM, Kumar Y
Neuroradiol J 2017 Aug;30(4):356-369. Epub 2017 Jun 19 doi: 10.1177/1971400917708582. PMID: 28627953Free PMC Article
Pirog EC
Semin Diagn Pathol 2015 Sep;32(5):409-18. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2015.02.015. PMID: 25862555
Stojanov IJ, Woo SB
Semin Diagn Pathol 2015 Jan;32(1):3-11. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.003. PMID: 25749203
Brenn T
Adv Anat Pathol 2014 Mar;21(2):108-30. doi: 10.1097/PAP.0000000000000009. PMID: 24508694

Recent systematic reviews

Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546Free PMC Article
Attlmayr B, Derbyshire SG, Kasbekar AV, Swift AC
J Laryngol Otol 2017 Apr;131(4):284-289. Epub 2017 Feb 9 doi: 10.1017/S0022215117000172. PMID: 28179032
Hosseinpour S, Mashhadiabbas F, Ahsaie MG
Pathol Oncol Res 2017 Jan;23(1):19-32. Epub 2016 Dec 6 doi: 10.1007/s12253-016-0150-x. PMID: 27924463
Driessen JP, van Kempen PM, van der Heijden GJ, Philippens ME, Pameijer FA, Stegeman I, Terhaard CH, Janssen LM, Grolman W
Head Neck 2015 Mar;37(3):440-8. Epub 2014 Feb 12 doi: 10.1002/hed.23575. PMID: 24347513
Zhang Y, Wang Y, Wan Z, Liu S, Cao Y, Zeng Z
PLoS One 2014;9(2):e90362. Epub 2014 Feb 27 doi: 10.1371/journal.pone.0090362. PMID: 24587339Free PMC Article

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