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Metastatic Kidney Carcinoma

MedGen UID:
1656418
•Concept ID:
C4745248
•
Neoplastic Process

Definition

A carcinoma that arises from the kidney and has metastasized to another anatomic site. [from NCI]

Professional guidelines

PubMed

Treatment Landscape of Renal Cell Carcinoma.
Chen YW, Wang L, Panian J, Dhanji S, Derweesh I, Rose B, Bagrodia A, McKay RR
Curr Treat Options Oncol 2023 Dec;24(12):1889-1916. Epub 2023 Dec 28 doi: 10.1007/s11864-023-01161-5. PMID: 38153686Free PMC Article
Renal cell carcinoma: an overview of the epidemiology, diagnosis, and treatment.
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Renal Cell Carcinoma: Diagnosis and Management.
Gray RE, Harris GT
Am Fam Physician 2019 Feb 1;99(3):179-184. PMID: 30702258

Recent clinical studies

Etiology

Prognostic factors of renal cell carcinoma.
Čechová M, Chocholatý M, Babjuk M, Kalousová M, Zima T
Rozhl Chir 2022 Fall;101(10):469-477. doi: 10.33699/PIS.2022.101.10.469-477. PMID: 36402558
The Role of Stereotactic Ablative Body Radiotherapy in Renal Cell Carcinoma.
Ali M, Mooi J, Lawrentschuk N, McKay RR, Hannan R, Lo SS, Hall WA, Siva S
Eur Urol 2022 Dec;82(6):613-622. Epub 2022 Jul 14 doi: 10.1016/j.eururo.2022.06.017. PMID: 35843777
Surgical and focal treatment for metastatic renal cell carcinoma: A literature review.
Naito S, Kato T, Tsuchiya N
Int J Urol 2022 Jun;29(6):494-501. Epub 2022 Mar 26 doi: 10.1111/iju.14841. PMID: 35340081
Is cytoreductive nephrectomy relevant in the immunotherapy era?
Singla N, Ghandour RA, Margulis V
Curr Opin Urol 2019 Sep;29(5):526-530. doi: 10.1097/MOU.0000000000000659. PMID: 31305273
Renal cell carcinoma.
Motzer RJ, Russo P, Nanus DM, Berg WJ
Curr Probl Cancer 1997 Jul-Aug;21(4):185-232. doi: 10.1016/s0147-0272(97)80007-4. PMID: 9285186

Diagnosis

Prognostic factors of renal cell carcinoma.
Čechová M, Chocholatý M, Babjuk M, Kalousová M, Zima T
Rozhl Chir 2022 Fall;101(10):469-477. doi: 10.33699/PIS.2022.101.10.469-477. PMID: 36402558
Nephrogenic epistaxis.
Kumar R, Sikka K, Kumar R, Chatterjee P
Singapore Med J 2014 Jul;55(7):e112-3. doi: 10.11622/smedj.2013185. PMID: 24379116Free PMC Article
Metastatic renal cell cancer.
Rasmussen F
Cancer Imaging 2013 Sep 23;13(3):374-80. doi: 10.1102/1470-7330.2013.9035. PMID: 24061106Free PMC Article
Renal cell carcinoma.
Godley PA, Taylor M
Curr Opin Oncol 2001 May;13(3):199-203. doi: 10.1097/00001622-200105000-00012. PMID: 11307065
Renal tumors.
Ruckle HC, Torres VE, Richardson RL, Zincke H
Curr Opin Nephrol Hypertens 1993 Mar;2(2):201-10. doi: 10.1097/00041552-199303000-00005. PMID: 7922178

Therapy

Immune Checkpoint Inhibitor Therapy Before Nephrectomy for Locally Advanced and Metastatic Renal Cell Carcinoma: A Review.
Ghoreifi A, Vaishampayan U, Yin M, Psutka SP, Djaladat H
JAMA Oncol 2024 Feb 1;10(2):240-248. doi: 10.1001/jamaoncol.2023.5269. PMID: 38095885
Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma.
Davidson G, Helleux A, Vano YA, Lindner V, Fattori A, Cerciat M, Elaidi RT, Verkarre V, Sun CM, Chevreau C, Bennamoun M, Lang H, Tricard T, Fridman WH, Sautes-Fridman C, Su X, Plassard D, Keime C, Thibault-Carpentier C, Barthelemy P, Oudard SM, Davidson I, Malouf GG
Cancer Res 2023 Sep 1;83(17):2952-2969. doi: 10.1158/0008-5472.CAN-22-3034. PMID: 37335139
Kidney Cancer: An Overview of Current Therapeutic Approaches.
Chowdhury N, Drake CG
Urol Clin North Am 2020 Nov;47(4):419-431. doi: 10.1016/j.ucl.2020.07.009. PMID: 33008493
Sunitinib.
Deeks ED, Keating GM
Drugs 2006;66(17):2255-66; discussion 2267-8. doi: 10.2165/00003495-200666170-00007. PMID: 17137406
Renal cell carcinoma.
Rini BI, Campbell SC, Rathmell WK
Curr Opin Oncol 2006 May;18(3):289-96. doi: 10.1097/01.cco.0000219260.60714.c4. PMID: 16552243

Prognosis

Renal Cell Carcinoma: A Review.
Rose TL, Kim WY
JAMA 2024 Sep 24;332(12):1001-1010. doi: 10.1001/jama.2024.12848. PMID: 39196544
Definitive radiotherapy in lieu of systemic therapy for oligometastatic renal cell carcinoma: a single-arm, single-centre, feasibility, phase 2 trial.
Tang C, Msaouel P, Hara K, Choi H, Le V, Shah AY, Wang J, Jonasch E, Choi S, Nguyen QN, Das P, Prajapati S, Yu Z, Khan K, Powell S, Murthy R, Sircar K, Tannir NM
Lancet Oncol 2021 Dec;22(12):1732-1739. Epub 2021 Oct 28 doi: 10.1016/S1470-2045(21)00528-3. PMID: 34717797
Open-Label, Single-Arm, Phase II Study of Pembrolizumab Monotherapy as First-Line Therapy in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma.
McDermott DF, Lee JL, Ziobro M, Suarez C, Langiewicz P, Matveev VB, Wiechno P, Gafanov RA, Tomczak P, Pouliot F, Donskov F, Alekseev BY, Shin SJ, Bjarnason GA, Castellano D, Silverman RK, Perini RF, Schloss C, Atkins MB
J Clin Oncol 2021 Mar 20;39(9):1029-1039. Epub 2021 Feb 2 doi: 10.1200/JCO.20.02365. PMID: 33529058Free PMC Article
Prognostic factors and prognostic models for renal cell carcinoma: a literature review.
Klatte T, Rossi SH, Stewart GD
World J Urol 2018 Dec;36(12):1943-1952. Epub 2018 Apr 30 doi: 10.1007/s00345-018-2309-4. PMID: 29713755
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.
Choueiri TK, Escudier B, Powles T, Tannir NM, Mainwaring PN, Rini BI, Hammers HJ, Donskov F, Roth BJ, Peltola K, Lee JL, Heng DYC, Schmidinger M, Agarwal N, Sternberg CN, McDermott DF, Aftab DT, Hessel C, Scheffold C, Schwab G, Hutson TE, Pal S, Motzer RJ; METEOR investigators
Lancet Oncol 2016 Jul;17(7):917-927. Epub 2016 Jun 5 doi: 10.1016/S1470-2045(16)30107-3. PMID: 27279544

Clinical prediction guides

Immune Checkpoint Inhibitor Therapy Before Nephrectomy for Locally Advanced and Metastatic Renal Cell Carcinoma: A Review.
Ghoreifi A, Vaishampayan U, Yin M, Psutka SP, Djaladat H
JAMA Oncol 2024 Feb 1;10(2):240-248. doi: 10.1001/jamaoncol.2023.5269. PMID: 38095885
Prognostic factors of renal cell carcinoma.
Čechová M, Chocholatý M, Babjuk M, Kalousová M, Zima T
Rozhl Chir 2022 Fall;101(10):469-477. doi: 10.33699/PIS.2022.101.10.469-477. PMID: 36402558
Surgical and focal treatment for metastatic renal cell carcinoma: A literature review.
Naito S, Kato T, Tsuchiya N
Int J Urol 2022 Jun;29(6):494-501. Epub 2022 Mar 26 doi: 10.1111/iju.14841. PMID: 35340081
Prognostic factors and prognostic models for renal cell carcinoma: a literature review.
Klatte T, Rossi SH, Stewart GD
World J Urol 2018 Dec;36(12):1943-1952. Epub 2018 Apr 30 doi: 10.1007/s00345-018-2309-4. PMID: 29713755
Predicting Oncologic Outcomes in Renal Cell Carcinoma After Surgery.
Leibovich BC, Lohse CM, Cheville JC, Zaid HB, Boorjian SA, Frank I, Thompson RH, Parker WP
Eur Urol 2018 May;73(5):772-780. Epub 2018 Feb 3 doi: 10.1016/j.eururo.2018.01.005. PMID: 29398265

Recent systematic reviews

First-line therapy for adults with advanced renal cell carcinoma: a systematic review and network meta-analysis.
Aldin A, Besiroglu B, Adams A, Monsef I, Piechotta V, Tomlinson E, Hornbach C, Dressen N, Goldkuhle M, Maisch P, Dahm P, Heidenreich A, Skoetz N
Cochrane Database Syst Rev 2023 May 4;5(5):CD013798. doi: 10.1002/14651858.CD013798.pub2. PMID: 37146227Free PMC Article
Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline.
Rathmell WK, Rumble RB, Van Veldhuizen PJ, Al-Ahmadie H, Emamekhoo H, Hauke RJ, Louie AV, Milowsky MI, Molina AM, Rose TL, Siva S, Zaorsky NG, Zhang T, Qamar R, Kungel TM, Lewis B, Singer EA
J Clin Oncol 2022 Sep 1;40(25):2957-2995. Epub 2022 Jun 21 doi: 10.1200/JCO.22.00868. PMID: 35728020
Adverse Events of Immune Checkpoint Inhibitors Therapy for Urologic Cancer Patients in Clinical Trials: A Collaborative Systematic Review and Meta-analysis.
Wu Z, Chen Q, Qu L, Li M, Wang L, Mir MC, Carbonara U, Pandolfo SD, Black PC, Paul AK, Di Lorenzo G, Porpiglia F, Mari A, Necchi A, Rouprêt M, Psutka SP, Autorino R
Eur Urol 2022 Apr;81(4):414-425. Epub 2022 Jan 31 doi: 10.1016/j.eururo.2022.01.028. PMID: 35101302
Genomics of Clear-cell Renal Cell Carcinoma: A Systematic Review and Meta-analysis.
Bui TO, Dao VT, Nguyen VT, Feugeas JP, Pamoukdjian F, Bousquet G
Eur Urol 2022 Apr;81(4):349-361. Epub 2022 Jan 3 doi: 10.1016/j.eururo.2021.12.010. PMID: 34991918
Association of Obesity With Survival Outcomes in Patients With Cancer: A Systematic Review and Meta-analysis.
Petrelli F, Cortellini A, Indini A, Tomasello G, Ghidini M, Nigro O, Salati M, Dottorini L, Iaculli A, Varricchio A, Rampulla V, Barni S, Cabiddu M, Bossi A, Ghidini A, Zaniboni A
JAMA Netw Open 2021 Mar 1;4(3):e213520. doi: 10.1001/jamanetworkopen.2021.3520. PMID: 33779745Free PMC Article

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