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Advanced Malignant Digestive System Neoplasm

MedGen UID:
1780145
Concept ID:
C5446611
Neoplastic Process

Definition

A malignant digestive system neoplasm that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Norwood DA, Montalvan-Sanchez E, Dominguez RL, Morgan DR
Gastroenterol Clin North Am 2022 Sep;51(3):501-518. doi: 10.1016/j.gtc.2022.05.001. PMID: 36153107
Biller LH, Schrag D
JAMA 2021 Feb 16;325(7):669-685. doi: 10.1001/jama.2021.0106. PMID: 33591350
Cappell MS
Gastroenterol Clin North Am 2008 Mar;37(1):1-24, v. doi: 10.1016/j.gtc.2007.12.002. PMID: 18313537

Recent clinical studies

Etiology

Wang D, Cabalag CS, Clemons NJ, DuBois RN
Gastroenterology 2021 Dec;161(6):1813-1829. Epub 2021 Oct 2 doi: 10.1053/j.gastro.2021.09.059. PMID: 34606846
Blay JY, Kang YK, Nishida T, von Mehren M
Nat Rev Dis Primers 2021 Mar 18;7(1):22. doi: 10.1038/s41572-021-00254-5. PMID: 33737510
Keung EZ, Raut CP, Rutkowski P
Ann Surg Oncol 2020 Oct;27(10):3659-3671. Epub 2020 Jul 30 doi: 10.1245/s10434-020-08869-w. PMID: 32734368Free PMC Article
von Mehren M, Joensuu H
J Clin Oncol 2018 Jan 10;36(2):136-143. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9705. PMID: 29220298Free PMC Article
Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, Shih T, Yao JC
JAMA Oncol 2017 Oct 1;3(10):1335-1342. doi: 10.1001/jamaoncol.2017.0589. PMID: 28448665Free PMC Article

Diagnosis

Blay JY, Kang YK, Nishida T, von Mehren M
Nat Rev Dis Primers 2021 Mar 18;7(1):22. doi: 10.1038/s41572-021-00254-5. PMID: 33737510
Pavel M, Öberg K, Falconi M, Krenning EP, Sundin A, Perren A, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2020 Jul;31(7):844-860. Epub 2020 Apr 6 doi: 10.1016/j.annonc.2020.03.304. PMID: 32272208
von Mehren M, Joensuu H
J Clin Oncol 2018 Jan 10;36(2):136-143. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9705. PMID: 29220298Free PMC Article
Song Z, Wu Y, Yang J, Yang D, Fang X
Tumour Biol 2017 Jul;39(7):1010428317714626. doi: 10.1177/1010428317714626. PMID: 28671042
Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, Shih T, Yao JC
JAMA Oncol 2017 Oct 1;3(10):1335-1342. doi: 10.1001/jamaoncol.2017.0589. PMID: 28448665Free PMC Article

Therapy

Janjigian YY, Van Cutsem E, Muro K, Wainberg Z, Al-Batran SE, Hyung WJ, Molena D, Marcovitz M, Ruscica D, Robbins SH, Negro A, Tabernero J
Future Oncol 2022 Jun;18(20):2465-2473. Epub 2022 May 10 doi: 10.2217/fon-2022-0093. PMID: 35535555
Schaefer IM, DeMatteo RP, Serrano C
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-15. doi: 10.1200/EDBK_351231. PMID: 35522913Free PMC Article
Chao J, Fuchs CS, Shitara K, Tabernero J, Muro K, Van Cutsem E, Bang YJ, De Vita F, Landers G, Yen CJ, Chau I, Elme A, Lee J, Özgüroglu M, Catenacci D, Yoon HH, Chen E, Adelberg D, Shih CS, Shah S, Bhagia P, Wainberg ZA
JAMA Oncol 2021 Jun 1;7(6):895-902. doi: 10.1001/jamaoncol.2021.0275. PMID: 33792646Free PMC Article
Blay JY, Kang YK, Nishida T, von Mehren M
Nat Rev Dis Primers 2021 Mar 18;7(1):22. doi: 10.1038/s41572-021-00254-5. PMID: 33737510
Keung EZ, Raut CP, Rutkowski P
Ann Surg Oncol 2020 Oct;27(10):3659-3671. Epub 2020 Jul 30 doi: 10.1245/s10434-020-08869-w. PMID: 32734368Free PMC Article

Prognosis

Xia JY, Aadam AA
J Surg Oncol 2022 Jun;125(7):1104-1109. doi: 10.1002/jso.26844. PMID: 35481909Free PMC Article
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Assarzadegan N, Montgomery E
Arch Pathol Lab Med 2021 Jun 1;145(6):664-677. doi: 10.5858/arpa.2019-0665-RA. PMID: 32233993Free PMC Article
Tan Z
Med Sci Monit 2019 May 13;25:3537-3541. doi: 10.12659/MSM.916475. PMID: 31080234Free PMC Article
Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, Shih T, Yao JC
JAMA Oncol 2017 Oct 1;3(10):1335-1342. doi: 10.1001/jamaoncol.2017.0589. PMID: 28448665Free PMC Article

Clinical prediction guides

Chen L, Shan G
Cancer Lett 2021 May 1;505:49-57. Epub 2021 Feb 18 doi: 10.1016/j.canlet.2021.02.004. PMID: 33609610
Assarzadegan N, Montgomery E
Arch Pathol Lab Med 2021 Jun 1;145(6):664-677. doi: 10.5858/arpa.2019-0665-RA. PMID: 32233993Free PMC Article
Nakamura Y, Taniguchi H, Ikeda M, Bando H, Kato K, Morizane C, Esaki T, Komatsu Y, Kawamoto Y, Takahashi N, Ueno M, Kagawa Y, Nishina T, Kato T, Yamamoto Y, Furuse J, Denda T, Kawakami H, Oki E, Nakajima T, Nishida N, Yamaguchi K, Yasui H, Goto M, Matsuhashi N, Ohtsubo K, Yamazaki K, Tsuji A, Okamoto W, Tsuchihara K, Yamanaka T, Miki I, Sakamoto Y, Ichiki H, Hata M, Yamashita R, Ohtsu A, Odegaard JI, Yoshino T
Nat Med 2020 Dec;26(12):1859-1864. Epub 2020 Oct 5 doi: 10.1038/s41591-020-1063-5. PMID: 33020649
Strosberg JR, Halfdanarson TR, Bellizzi AM, Chan JA, Dillon JS, Heaney AP, Kunz PL, O'Dorisio TM, Salem R, Segelov E, Howe JR, Pommier RF, Brendtro K, Bashir MA, Singh S, Soulen MC, Tang L, Zacks JS, Yao JC, Bergsland EK
Pancreas 2017 Jul;46(6):707-714. doi: 10.1097/MPA.0000000000000850. PMID: 28609356Free PMC Article
Sorbye H, Welin S, Langer SW, Vestermark LW, Holt N, Osterlund P, Dueland S, Hofsli E, Guren MG, Ohrling K, Birkemeyer E, Thiis-Evensen E, Biagini M, Gronbaek H, Soveri LM, Olsen IH, Federspiel B, Assmus J, Janson ET, Knigge U
Ann Oncol 2013 Jan;24(1):152-60. Epub 2012 Sep 11 doi: 10.1093/annonc/mds276. PMID: 22967994

Recent systematic reviews

Cheng V, Oveisi N, McTaggart-Cowan H, Loree JM, Murphy RA, De Vera MA
Curr Oncol 2022 Nov 15;29(11):8751-8766. doi: 10.3390/curroncol29110689. PMID: 36421342Free PMC Article
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Gosavi R, Chia C, Michael M, Heriot AG, Warrier SK, Kong JC
Int J Colorectal Dis 2021 Oct;36(10):2063-2070. Epub 2021 May 4 doi: 10.1007/s00384-021-03945-3. PMID: 33945007
Kasi A, Abbasi S, Handa S, Al-Rajabi R, Saeed A, Baranda J, Sun W
JAMA Netw Open 2020 Dec 1;3(12):e2030097. doi: 10.1001/jamanetworkopen.2020.30097. PMID: 33326026Free PMC Article

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