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Disorder of mediastinum

MedGen UID:
44321
Concept ID:
C0025061
Disease or Syndrome
Synonyms: Disease, Mediastinal; Diseases, Mediastinal; Mediastinal Disease; Mediastinal Diseases
SNOMED CT: Disorder of mediastinum (49483002); Mediastinal disorder (49483002); Mediastinal disease (49483002)

Definition

A non-neoplastic or neoplastic disorder that affects the structures of the mediastinum. Representative examples include mediastinitis, mediastinal lipoma, mediastinal schwannoma, thymoma, and mediastinal lymphoma. [from NCI]

Professional guidelines

PubMed

Aljudi A, Weinzierl E, Elkhalifa M, Park S
Clin Lab Med 2021 Sep;41(3):389-404. Epub 2021 Jul 3 doi: 10.1016/j.cll.2021.03.011. PMID: 34304771
Zhang ML, Sohani AR
Semin Diagn Pathol 2020 Jul;37(4):156-165. Epub 2020 May 15 doi: 10.1053/j.semdp.2020.04.005. PMID: 32451144
Munden RF, Carter BW, Chiles C, MacMahon H, Black WC, Ko JP, McAdams HP, Rossi SE, Leung AN, Boiselle PM, Kent MS, Brown K, Dyer DS, Hartman TE, Goodman EM, Naidich DP, Kazerooni EA, Berland LL, Pandharipande PV
J Am Coll Radiol 2018 Aug;15(8):1087-1096. Epub 2018 Jun 22 doi: 10.1016/j.jacr.2018.04.029. PMID: 29941240

Recent clinical studies

Etiology

Fan Y, Zhang AM, Wu XL, Huang ZS, Kontogianni K, Sun K, Fu WL, Wu N, Kuebler WM, Herth FJF
Lancet Respir Med 2023 Mar;11(3):256-264. Epub 2022 Oct 22 doi: 10.1016/S2213-2600(22)00392-7. PMID: 36279880
DeVivo A, Sheng AY, Koyfman A, Long B
Am J Emerg Med 2022 Mar;53:29-36. Epub 2021 Dec 18 doi: 10.1016/j.ajem.2021.12.017. PMID: 34971919
Sohda M, Saeki H, Kuwano H, Sakai M, Sano A, Yokobori T, Miyazaki T, Kakeji Y, Toh Y, Doki Y, Matsubara H
Esophagus 2022 Jan;19(1):175-181. Epub 2021 Jun 11 doi: 10.1007/s10388-021-00858-6. PMID: 34117586
Balakrishnan K, Fonacier F, Sood S, Bamji N, Bostwick H, Stringel G
JSLS 2017 Apr-Jun;21(2) doi: 10.4293/JSLS.2017.00017. PMID: 28642639Free PMC Article
Kaiser LR, Bavaria JE
Ann Thorac Surg 1993 Sep;56(3):796-8. doi: 10.1016/0003-4975(93)90983-o. PMID: 8379796

Diagnosis

Chew FY, Yang ST
CMAJ 2021 Sep 27;193(38):E1499. doi: 10.1503/cmaj.202893. PMID: 34580144Free PMC Article
Iyer H, Anand A, Sryma PB, Gupta K, Naranje P, Damle N, Mittal S, Madan NK, Mohan A, Hadda V, Tiwari P, Guleria R, Madan K
Expert Rev Respir Med 2021 Oct;15(10):1317-1334. Epub 2021 May 6 doi: 10.1080/17476348.2021.1920404. PMID: 33888038
Kocaman G, Yenigün BM, Çoruh AG, Koçak EM, Memmedyarow İ, Tural M, Sak SD, Yazıcıoğlu L, Akal RM
Gen Thorac Cardiovasc Surg 2020 Sep;68(9):1051-1054. Epub 2019 Oct 3 doi: 10.1007/s11748-019-01211-6. PMID: 31583517
Priola AM, Priola SM, Cardinale L, Cataldi A, Fava C
Radiol Med 2006 Apr;111(3):312-42. Epub 2006 Apr 11 doi: 10.1007/s11547-006-0032-5. PMID: 16683081
Laurent F, Latrabe V, Lecesne R, Zennaro H, Airaud JY, Rauturier JF, Drouillard J
Eur Radiol 1998;8(7):1148-59. doi: 10.1007/s003300050525. PMID: 9724429

Therapy

Fan Y, Zhang AM, Wu XL, Huang ZS, Kontogianni K, Sun K, Fu WL, Wu N, Kuebler WM, Herth FJF
Lancet Respir Med 2023 Mar;11(3):256-264. Epub 2022 Oct 22 doi: 10.1016/S2213-2600(22)00392-7. PMID: 36279880
Chew FY, Yang ST
CMAJ 2021 Sep 27;193(38):E1499. doi: 10.1503/cmaj.202893. PMID: 34580144Free PMC Article
Madan K, Iyer H, Madan NK, Mittal S, Tiwari P, Hadda V, Mohan A, Pandey RM, Kabra SK, Guleria R
Pediatr Pulmonol 2021 Jan;56(1):23-33. Epub 2020 Oct 29 doi: 10.1002/ppul.25124. PMID: 33073498
Dasari BV, Neely D, Kennedy A, Spence G, Rice P, Mackle E, Epanomeritakis E
Ann Surg 2014 May;259(5):852-60. doi: 10.1097/SLA.0000000000000564. PMID: 24509201
Kirschner PA
Chest Surg Clin N Am 1996 Feb;6(1):1-20. PMID: 8646496

Prognosis

Das JP, Xie L, Riedl CC, Hayes SA, Ginsberg MS, Halpenny DF
Br J Radiol 2019 Dec;92(1104):20190473. Epub 2019 Aug 14 doi: 10.1259/bjr.20190473. PMID: 31386554Free PMC Article
Cabral FC, Trotman-Dickenson B, Madan R
Eur J Radiol 2015 Mar;84(3):489-498. Epub 2014 Dec 15 doi: 10.1016/j.ejrad.2014.11.039. PMID: 25557510
Chirica M, Champault A, Dray X, Sulpice L, Munoz-Bongrand N, Sarfati E, Cattan P
J Visc Surg 2010 Jun;147(3):e117-28. Epub 2010 Sep 15 doi: 10.1016/j.jviscsurg.2010.08.003. PMID: 20833121
Henzler T, Schmid-Bindert G, Schoenberg SO, Fink C
Eur J Radiol 2010 Dec;76(3):329-36. doi: 10.1016/j.ejrad.2010.05.005. PMID: 20627435
Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR
Radiographics 2001 May-Jun;21(3):737-57. doi: 10.1148/radiographics.21.3.g01ma17737. PMID: 11353121

Clinical prediction guides

Tan A, Nolan JA
Paediatr Anaesth 2022 Jan;32(1):4-9. Epub 2021 Nov 14 doi: 10.1111/pan.14319. PMID: 34714957
Cabral FC, Trotman-Dickenson B, Madan R
Eur J Radiol 2015 Mar;84(3):489-498. Epub 2014 Dec 15 doi: 10.1016/j.ejrad.2014.11.039. PMID: 25557510
Chirica M, Champault A, Dray X, Sulpice L, Munoz-Bongrand N, Sarfati E, Cattan P
J Visc Surg 2010 Jun;147(3):e117-28. Epub 2010 Sep 15 doi: 10.1016/j.jviscsurg.2010.08.003. PMID: 20833121
Henzler T, Schmid-Bindert G, Schoenberg SO, Fink C
Eur J Radiol 2010 Dec;76(3):329-36. doi: 10.1016/j.ejrad.2010.05.005. PMID: 20627435
Thomas CR Jr, Bonomi PD
Curr Opin Oncol 1991 Apr;3(2):335-43. doi: 10.1097/00001622-199104000-00015. PMID: 1648973

Recent systematic reviews

Madan K, Iyer H, Madan NK, Mittal S, Tiwari P, Hadda V, Mohan A, Pandey RM, Kabra SK, Guleria R
Pediatr Pulmonol 2021 Jan;56(1):23-33. Epub 2020 Oct 29 doi: 10.1002/ppul.25124. PMID: 33073498
Mitsos S, Stamatopoulos A, Patrini D, George RS, Lawrence DR, Panagiotopoulos N
Adv Respir Med 2018;86(1):36-43. doi: 10.5603/ARM.2018.0008. PMID: 29490420
Fernández-Villar A, Mouronte-Roibás C, Botana-Rial M, Ruano-Raviña A
Arch Bronconeumol 2016 Feb;52(2):96-102. Epub 2015 Nov 10 doi: 10.1016/j.arbres.2015.08.007. PMID: 26565072
Wahidi MM, Herth F, Yasufuku K, Shepherd RW, Yarmus L, Chawla M, Lamb C, Casey KR, Patel S, Silvestri GA, Feller-Kopman DJ
Chest 2016 Mar;149(3):816-35. Epub 2016 Jan 12 doi: 10.1378/chest.15-1216. PMID: 26402427
von Bartheld MB, van Breda A, Annema JT
Respiration 2014;87(4):343-51. Epub 2014 Jan 16 doi: 10.1159/000357066. PMID: 24434575

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