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Abnormality of lipoprotein cholesterol concentration

MedGen UID:
869193
•Concept ID:
C4023615
•
Finding
Synonym: Abnormality of the level of lipoprotein cholesterol
 
HPO: HP:0010979

Definition

An abnormal increase or decrease in the level of lipoprotein cholesterol in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of lipoprotein cholesterol concentration

Professional guidelines

PubMed

Follow-Up Study of Growth Hormone Therapy in Children with Kabuki Syndrome: Two-Year Treatment Results.
van Montfort L, Gerver WJM, Kooger BLS, Plat J, Bierau J, Stumpel CTRM, Schott DA
Horm Res Paediatr 2021;94(7-8):285-296. Epub 2021 Oct 4 doi: 10.1159/000519963. PMID: 34607328
Apolipoprotein profiling as a personalized approach to the diagnosis and treatment of dyslipidaemia.
Renee Ruhaak L, van der Laarse A, Cobbaert CM
Ann Clin Biochem 2019 May;56(3):338-356. Epub 2019 Mar 19 doi: 10.1177/0004563219827620. PMID: 30889974Free PMC Article
Pathophysiology and treatment of the dyslipidemia of insulin resistance.
Cohn G, Valdes G, Capuzzi DM
Curr Cardiol Rep 2001 Sep;3(5):416-23. doi: 10.1007/s11886-001-0059-0. PMID: 11504579

Recent clinical studies

Etiology

Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome.
Guevara-Cruz M, Flores-López AG, Aguilar-López M, Sánchez-Tapia M, Medina-Vera I, Díaz D, Tovar AR, Torres N
J Am Heart Assoc 2019 Sep 3;8(17):e012401. Epub 2019 Aug 27 doi: 10.1161/JAHA.119.012401. PMID: 31451009Free PMC Article
Effects of thyroid hormone and depression on common components of central obesity.
Du FM, Kuang HY, Duan BH, Liu DN, Yu XY
J Int Med Res 2019 Jul;47(7):3040-3049. Epub 2019 May 30 doi: 10.1177/0300060519851624. PMID: 31144547Free PMC Article
Role of PCSK9 in lipid metabolic disorders and ovarian dysfunction in polycystic ovary syndrome.
Wang M, Zhao D, Xu L, Guo W, Nie L, Lei Y, Long Y, Liu M, Wang Y, Zhang X, Zhang L, Li H, Zhang J, Yuan D, Yue L
Metabolism 2019 May;94:47-58. Epub 2019 Feb 12 doi: 10.1016/j.metabol.2019.02.002. PMID: 30768966
Subclinical hypothyroidism.
Papi G, Uberti ED, Betterle C, Carani C, Pearce EN, Braverman LE, Roti E
Curr Opin Endocrinol Diabetes Obes 2007 Jun;14(3):197-208. doi: 10.1097/MED.0b013e32803577e7. PMID: 17940439
Diabetic dyslipidemia.
Betteridge DJ
Am J Med 1994 Jun 6;96(6A):25S-31S. doi: 10.1016/0002-9343(94)90228-3. PMID: 8017462

Diagnosis

Effects of bariatric surgery on lipid-lipoprotein profile.
Piché ME, Tardif I, Auclair A, Poirier P
Metabolism 2021 Feb;115:154441. Epub 2020 Nov 25 doi: 10.1016/j.metabol.2020.154441. PMID: 33248063
High-density lipoprotein cholesterol concentration and acute kidney injury after noncardiac surgery.
Zhou Y, Yang HY, Zhang HL, Zhu XJ
BMC Nephrol 2020 Apr 25;21(1):149. doi: 10.1186/s12882-020-01808-7. PMID: 32334566Free PMC Article
Apolipoprotein profiling as a personalized approach to the diagnosis and treatment of dyslipidaemia.
Renee Ruhaak L, van der Laarse A, Cobbaert CM
Ann Clin Biochem 2019 May;56(3):338-356. Epub 2019 Mar 19 doi: 10.1177/0004563219827620. PMID: 30889974Free PMC Article
Role of PCSK9 in lipid metabolic disorders and ovarian dysfunction in polycystic ovary syndrome.
Wang M, Zhao D, Xu L, Guo W, Nie L, Lei Y, Long Y, Liu M, Wang Y, Zhang X, Zhang L, Li H, Zhang J, Yuan D, Yue L
Metabolism 2019 May;94:47-58. Epub 2019 Feb 12 doi: 10.1016/j.metabol.2019.02.002. PMID: 30768966
Statins and diabetes.
Carmena R, Betteridge DJ
Semin Vasc Med 2004 Nov;4(4):321-32. doi: 10.1055/s-2004-869589. PMID: 15861314

Therapy

Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome.
Guevara-Cruz M, Flores-López AG, Aguilar-López M, Sánchez-Tapia M, Medina-Vera I, Díaz D, Tovar AR, Torres N
J Am Heart Assoc 2019 Sep 3;8(17):e012401. Epub 2019 Aug 27 doi: 10.1161/JAHA.119.012401. PMID: 31451009Free PMC Article
Effects of thyroid hormone and depression on common components of central obesity.
Du FM, Kuang HY, Duan BH, Liu DN, Yu XY
J Int Med Res 2019 Jul;47(7):3040-3049. Epub 2019 May 30 doi: 10.1177/0300060519851624. PMID: 31144547Free PMC Article
Alterations of specific lipid groups in serum of obese humans: a review.
Mika A, Sledzinski T
Obes Rev 2017 Feb;18(2):247-272. Epub 2016 Nov 29 doi: 10.1111/obr.12475. PMID: 27899022
Statins and diabetes.
Carmena R, Betteridge DJ
Semin Vasc Med 2004 Nov;4(4):321-32. doi: 10.1055/s-2004-869589. PMID: 15861314
Dichloroacetate.
Stacpoole PW, Greene YJ
Diabetes Care 1992 Jun;15(6):785-91. doi: 10.2337/diacare.15.6.785. PMID: 1600837

Prognosis

Lipocalin-2 and insulin as new biomarkers of alopecia areata.
Waśkiel-Burnat A, Niemczyk A, Chmielińska P, Muszel M, Zaremba M, Rakowska A, Olszewska M, Rudnicka L
PLoS One 2022;17(5):e0268086. Epub 2022 May 31 doi: 10.1371/journal.pone.0268086. PMID: 35639706Free PMC Article
Effects of thyroid hormone and depression on common components of central obesity.
Du FM, Kuang HY, Duan BH, Liu DN, Yu XY
J Int Med Res 2019 Jul;47(7):3040-3049. Epub 2019 May 30 doi: 10.1177/0300060519851624. PMID: 31144547Free PMC Article
Current and future therapies for addressing the effects of inflammation on HDL cholesterol metabolism.
Iqbal F, Baker WS, Khan MI, Thukuntla S, McKinney KH, Abate N, Tuvdendorj D
Br J Pharmacol 2017 Nov;174(22):3986-4006. Epub 2017 Mar 23 doi: 10.1111/bph.13743. PMID: 28326542Free PMC Article
Could high-density lipoprotein cholesterol predict increased cardiovascular risk?
Chang TI, Streja E, Moradi H
Curr Opin Endocrinol Diabetes Obes 2017 Apr;24(2):140-147. doi: 10.1097/MED.0000000000000318. PMID: 28099207
Subclinical thyroid disease.
Wilson GR, Curry RW Jr
Am Fam Physician 2005 Oct 15;72(8):1517-24. PMID: 16273818

Clinical prediction guides

High-density lipoprotein cholesterol concentration and acute kidney injury after noncardiac surgery.
Zhou Y, Yang HY, Zhang HL, Zhu XJ
BMC Nephrol 2020 Apr 25;21(1):149. doi: 10.1186/s12882-020-01808-7. PMID: 32334566Free PMC Article
Effects of thyroid hormone and depression on common components of central obesity.
Du FM, Kuang HY, Duan BH, Liu DN, Yu XY
J Int Med Res 2019 Jul;47(7):3040-3049. Epub 2019 May 30 doi: 10.1177/0300060519851624. PMID: 31144547Free PMC Article
Current and future therapies for addressing the effects of inflammation on HDL cholesterol metabolism.
Iqbal F, Baker WS, Khan MI, Thukuntla S, McKinney KH, Abate N, Tuvdendorj D
Br J Pharmacol 2017 Nov;174(22):3986-4006. Epub 2017 Mar 23 doi: 10.1111/bph.13743. PMID: 28326542Free PMC Article
Could high-density lipoprotein cholesterol predict increased cardiovascular risk?
Chang TI, Streja E, Moradi H
Curr Opin Endocrinol Diabetes Obes 2017 Apr;24(2):140-147. doi: 10.1097/MED.0000000000000318. PMID: 28099207
Lipoprotein metabolism and CKD: overview.
Barter P
Clin Exp Nephrol 2014 Apr;18(2):243-6. Epub 2013 Sep 20 doi: 10.1007/s10157-013-0866-9. PMID: 24052157

Recent systematic reviews

The impact of Emblica Officinalis (Amla) on lipid profile, glucose, and C-reactive protein: A systematic review and meta-analysis of randomized controlled trials.
Setayesh L, Haghighat N, Rasaei N, Rezaei M, Casazza K, Nadery M, Yamrali I, Zamani M, Asbaghi O
Diabetes Metab Syndr 2023 Mar;17(3):102729. Epub 2023 Mar 11 doi: 10.1016/j.dsx.2023.102729. PMID: 36934568
The effects of phytosterol and phytostanol supplementation on the lipid profile in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials.
Xia W, Xiang S, Gaman MA, Jamilian P, Prabahar K, Du G, Gao D
Phytother Res 2022 Dec;36(12):4398-4408. Epub 2022 Sep 30 doi: 10.1002/ptr.7646. PMID: 36180973
Weight Loss and Serum Lipids in Overweight and Obese Adults: A Systematic Review and Meta-Analysis.
Hasan B, Nayfeh T, Alzuabi M, Wang Z, Kuchkuntla AR, Prokop LJ, Newman CB, Murad MH, Rajjo TI
J Clin Endocrinol Metab 2020 Dec 1;105(12) doi: 10.1210/clinem/dgaa673. PMID: 32954416
Effect of inulin-type fructans on blood lipid profile and glucose level: a systematic review and meta-analysis of randomized controlled trials.
Liu F, Prabhakar M, Ju J, Long H, Zhou HW
Eur J Clin Nutr 2017 Jan;71(1):9-20. Epub 2016 Sep 14 doi: 10.1038/ejcn.2016.156. PMID: 27623982
A systematic review of the clinical effectiveness of pioglitazone in the treatment of type 2 diabetes mellitus.
Chilcott J, Tappenden P, Jones ML, Wight JP
Clin Ther 2001 Nov;23(11):1792-823; discussion 1791. doi: 10.1016/s0149-2918(00)80078-8. PMID: 11768834

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