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Status
Public on Mar 28, 2009
Title
Pathwork Diagnostics Pathchip
Technology type
in situ oligonucleotide
Distribution
commercial
Organism
Homo sapiens
Manufacturer
Affymetrix, for Pathwork Diagnostics, Inc.
Manufacture protocol
see manufacturer's web site for U133A
Description
An FDA-cleared GeneChip platform for the Tissue Of Origin (TOO) cancer diagnostic test. Based on Affymetrix U133A array. Keywords = high density oligonucleotide array
Submission date
Sep 10, 2008
Last update date
Mar 28, 2009
Contact name
Ljubomir Buturovic
Organization name
Pathwork Diagnostics
Department
Application Development
Street address
1196 Borregas Avenue
City
Sunnyvale
State/province
CA
ZIP/Postal code
94089
Country
USA
Samples (165)
GSM319520 , GSM319521 , GSM319522 , GSM319523 , GSM319524 , GSM319525
GSM319526 ,
GSM319527 ,
GSM319528 ,
GSM319529 ,
GSM319530 ,
GSM319531 ,
GSM319532 ,
GSM319533 ,
GSM319534 ,
GSM319535 ,
GSM319536 ,
GSM319537 ,
GSM319538 ,
GSM319539 ,
GSM319540 ,
GSM319541 ,
GSM319542 ,
GSM319543 ,
GSM319544 ,
GSM319545 ,
GSM319546 ,
GSM319547 ,
GSM319548 ,
GSM319549 ,
GSM319550 ,
GSM319551 ,
GSM319552 ,
GSM319553 ,
GSM319554 ,
GSM319555 ,
GSM319556 ,
GSM319557 ,
GSM319558 ,
GSM319559 ,
GSM319560 ,
GSM319561 ,
GSM319562 ,
GSM319563 ,
GSM319564 ,
GSM319565 ,
GSM319566 ,
GSM319567 ,
GSM319568 ,
GSM319569 ,
GSM319570 ,
GSM319571 ,
GSM319572 ,
GSM319573 ,
GSM319574 ,
GSM319575 ,
GSM319576 ,
GSM319577 ,
GSM319578 ,
GSM319579 ,
GSM319580 ,
GSM319581 ,
GSM319582 ,
GSM319583 ,
GSM319584 ,
GSM319585 ,
GSM319586 ,
GSM319587 ,
GSM319588 ,
GSM319589 ,
GSM319590 ,
GSM319591 ,
GSM319592 ,
GSM319593 ,
GSM319594 ,
GSM319595 ,
GSM319596 ,
GSM319597 ,
GSM319598 ,
GSM319599 ,
GSM319600 ,
GSM319601 ,
GSM319602 ,
GSM319603 ,
GSM319604 ,
GSM319605 ,
GSM319606 ,
GSM319607 ,
GSM319608 ,
GSM1079947 ,
GSM1079948 ,
GSM1079949 ,
GSM1079950 ,
GSM1079951 ,
GSM1079952 ,
GSM1079953 ,
GSM1079954 ,
GSM1079955 ,
GSM1079956 ,
GSM1079957 ,
GSM1079958 ,
GSM1079959 ,
GSM1079960 ,
GSM1079961 ,
GSM1079962 ,
GSM1079963 ,
GSM1079964 ,
GSM1079965 ,
GSM1079966 ,
GSM1079967 ,
GSM1079968 ,
GSM1079969 ,
GSM1079970 ,
GSM1079971 ,
GSM1079972 ,
GSM1079973 ,
GSM1079974 ,
GSM1079975 ,
GSM1079976 ,
GSM1079977 ,
GSM1079978 ,
GSM1079979 ,
GSM1079980 ,
GSM1079981 ,
GSM1079982 ,
GSM1079983 ,
GSM1079984 ,
GSM1079985 ,
GSM1079986 ,
GSM1079987 ,
GSM1079988 ,
GSM1079989 ,
GSM1079990 ,
GSM1079991 ,
GSM1079992 ,
GSM1079993 ,
GSM1079994 ,
GSM1079995 ,
GSM1079996 ,
GSM1079997 ,
GSM1079998 ,
GSM1079999 ,
GSM1080000 ,
GSM1080001 ,
GSM1080002 ,
GSM1080003 ,
GSM1080004 ,
GSM1080005 ,
GSM1080006 ,
GSM1080007 ,
GSM1080008 ,
GSM1080009 ,
GSM1080010 ,
GSM1080011 ,
GSM1080012 ,
GSM1080013 ,
GSM1080014 ,
GSM1080015 ,
GSM1080016 ,
GSM1080017 ,
GSM1080018 ,
GSM1080019 ,
GSM1080020 ,
GSM1080021 ,
GSM1080022
Series (2)
GSE12630
Gene expression profiles of poorly differentiated, undifferentiated and metastatic cancers
GSE44170
Gene expression profiles of Head & Neck Squamous and Lung Squamous Cancers
Data table header descriptions
ID
GB_ACC
SPOT_ID
Species Scientific Name
Annotation Date
Sequence Type
Sequence Source
Target Description
Representative Public ID
Gene Title
Gene Symbol
ENTREZ_GENE_ID
RefSeq Transcript ID
Gene Ontology Biological Process
Gene Ontology Cellular Component
Gene Ontology Molecular Function
Data table
ID
GB_ACC
SPOT_ID
Species Scientific Name
Annotation Date
Sequence Type
Sequence Source
Target Description
Representative Public ID
Gene Title
Gene Symbol
ENTREZ_GENE_ID
RefSeq Transcript ID
Gene Ontology Biological Process
Gene Ontology Cellular Component
Gene Ontology Molecular Function
pw-596665
U48705
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
U48705 /FEATURE=mRNA /DEFINITION=HSU48705 Human receptor tyrosine kinase DDR gene, complete cds
U48705
discoidin domain receptor family, member 1
DDR1
780
NM_001954 /// NM_013993 /// NM_013994
0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation
0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation
0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein-tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
pw-569502
M87338
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
M87338 /FEATURE= /DEFINITION=HUMA1SBU Human replication factor C, 40-kDa subunit (A1) mRNA, complete cds
M87338
replication factor C (activator 1) 2, 40kDa
RFC2
5982
NM_002914 /// NM_181471
0006260 // DNA replication // inferred from electronic annotation
0005634 // nucleus // inferred from electronic annotation /// 0005663 // DNA replication factor C complex // traceable author statement
0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation
pw-575949
X51757
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
X51757 /FEATURE=cds /DEFINITION=HSP70B Human heat-shock protein HSP70B' gene
X51757
heat shock 70kDa protein 6 (HSP70B')
HSPA6
3310
NM_002155 /// XM_001134322
0006986 // response to unfolded protein // traceable author statement
0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation
pw-579445
X69699
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
X69699 /FEATURE= /DEFINITION=HSPAX8A H.sapiens Pax8 mRNA
X69699
paired box gene 8
PAX8
7849
NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992
0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from sequence or structural similarity
0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity
0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016563 // transcriptional activator activity // inferred from sequence or structural similarity
pw-597565
L36861
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
L36861 /FEATURE=expanded_cds /DEFINITION=HUMGCAPB Homo sapiens guanylate cyclase activating protein (GCAP) gene exons 1-4, complete cds
L36861
guanylate cyclase activator 1A (retina)
GUCA1A
2978
NM_000409
0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation
0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // traceable author statement /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation
pw-590607
L13852
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
L13852 /FEATURE= /DEFINITION=HUME1URP Homo sapiens ubiquitin-activating enzyme E1 related protein mRNA, complete cds
L13852
ubiquitin-activating enzyme E1-like
UBE1L
7318
NM_003335
0006464 // protein modification process // inferred from electronic annotation /// 0006464 // protein modification process // inferred from direct assay /// 0006512 // ubiquitin cycle // inferred from electronic annotation /// 0032020 // ISG15-protein conjugation // inferred from direct assay
0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay
pw-554370
X55005
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
X55005 /FEATURE=mRNA /DEFINITION=HSCERBAR Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene)
X55005
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
THRA
7067
NM_003250 /// NM_199334
0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006351 // transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from electronic annotation
0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement
0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016564 // transcriptional repressor activity // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
pw-577539
X79510
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
X79510 /FEATURE=cds /DEFINITION=HSPTPD1 H.sapiens mRNA for protein-tyrosine-phosphatase D1
X79510
protein tyrosine phosphatase, non-receptor type 21
PTPN21
11099
NM_007039
0006470 // protein amino acid dephosphorylation // traceable author statement /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation
0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation
0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphoric monoester hydrolase activity // inferred from electronic annotation
pw-508863
M21121
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
M21121 /FEATURE= /DEFINITION=HUMTCSM Human T cell-specific protein (RANTES) mRNA, complete cds
M21121
chemokine (C-C motif) ligand 5
CCL5
6352
NM_002985
0006874 // calcium ion homeostasis // traceable author statement /// 0006887 // exocytosis // traceable author statement /// 0006928 // cell motility // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009615 // response to virus // traceable author statement
0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation
0004871 // signal transducer activity // traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008009 // chemokine activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay
pw-544128
J02843
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
J02843 /FEATURE=cds /DEFINITION=HUMCYPIIE Human cytochrome P450IIE1 (ethanol-inducible) gene, complete cds
J02843
cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2E1
1571
NM_000773
0006118 // electron transport // inferred from electronic annotation
0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation
0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050381 // unspecific monooxygenase activity // inferred from electronic annotation
pw-579568
X75208
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
X75208 /FEATURE=cds /DEFINITION=HSPTKR H.sapiens HEK2 mRNA for protein tyrosine kinase receptor
X75208
EPH receptor B3
EPHB3
2049
NM_004443
0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation
0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation
0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein-tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
pw-523411
L38487
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
L38487 /FEATURE=mRNA /DEFINITION=HUMHERRA1 Human estrogen receptor-related protein (hERRa1) mRNA, 3' end, partial cds
L38487
estrogen-related receptor alpha
ESRRA
2101
NM_004451
0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation
0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement
0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016439 // tRNA-pseudouridine synthase activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
pw-520715
M33318
Homo sapiens
Jul 11, 2007
Exemplar sequence
Affymetrix Proprietary Database
M33318 /FEATURE=mRNA /DEFINITION=HUMCPIIA3A Human cytochrome P450IIA3 (CYP2A3) mRNA, complete cds
M33318
cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A6
1548
NM_000762
0006118 // electron transport // inferred from electronic annotation
0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005792 // microsome // traceable author statement /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation
0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050381 // unspecific monooxygenase activity // inferred from electronic annotation
pw-550198
L13720
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
L13720 /FEATURE= /DEFINITION=HUMGAS Homo sapiens growth-arrest-specific protein (gas) mRNA, complete cds
L13720
growth arrest-specific 6
GAS6
2621
NM_000820
0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement
0005576 // extracellular region // inferred from electronic annotation
0005102 // receptor binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
pw-597436
Z48481
Homo sapiens
Jul 11, 2007
Consensus sequence
GenBank
Z48481 /FEATURE=cds /DEFINITION=HSMMPM1 H.sapiens mRNA for membrane-type matrix metalloproteinase 1 /NOTE=replacement of probe set 1301_s_at
Z48481
matrix metallopeptidase 14 (membrane-inserted)
MMP14
4323
NM_004995
0000270 // peptidoglycan metabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation
0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation
0004222 // metalloendopeptidase activity // traceable author statement /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
pw-519239
L41690
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
L41690 /FEATURE= /DEFINITION=HUMTRADD Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds
L41690
TNFRSF1A-associated via death domain
TRADD
8717
NM_003789 /// NM_153425
0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from expression pattern
0004871 // signal transducer activity // inferred from expression pattern /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction
pw-503583
L00635
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
L00635 /FEATURE= /DEFINITION=HUMFPTB Human farnesyl-protein transferase beta-subunit mRNA, complete cds
L00635
farnesyltransferase, CAAX box, beta
FNTB
2342
NM_002028
0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0018347 // protein amino acid farnesylation // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation
0005737 // cytoplasm // not recorded
0003824 // catalytic activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // traceable author statement /// 0004660 // protein farnesyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
pw-543132
U38545
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
U38545 /FEATURE= /DEFINITION=HSU38545 Human ARF-activated phosphatidylcholine-specific phospholipase D1a (hPLD1) mRNA, complete cds
U38545
phospholipase D1, phosphatidylcholine-specific
PLD1
5337
NM_002662
0006644 // phospholipid metabolic process // not recorded /// 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation
0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation
0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation
pw-591165
U38980
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
U38980 /FEATURE= /DEFINITION=U38980 Human PMS2 related (hPMSR6) mRNA, complete cds
U38980
postmeiotic segregation increased 2-like 11
PMS2L11
441263
XM_499450
0006298 // mismatch repair // inferred from electronic annotation
0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from electronic annotation
pw-535891
U66879
Homo sapiens
Jul 11, 2007
Exemplar sequence
GenBank
U66879 /FEATURE= /DEFINITION=HSU66879 Human Bcl-2 binding component 6 (bbc6) mRNA, complete cds
U66879
BCL2-antagonist of cell death
BAD
572
NM_004322 /// NM_032989
0006007 // glucose catabolic process // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // non-traceable author statement /// 0008624 // induction of apoptosis by extracellular signals // inferred from electronic annotation /// 0008632 // apoptotic program // traceable author statement /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation
0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // non-traceable author statement
0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement
Total number of rows: 22300 Table truncated, full table size 23436 Kbytes .
Supplementary file
Size
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File type/resource
GPL7280_PathChipd520393.CDF.gz
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