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Metastatic Malignant Digestive System Neoplasm

MedGen UID:
1695139
Concept ID:
C5206464
Neoplastic Process

Definition

A malignant neoplasm that arises in the digestive system and has spread from its original site of growth to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Digestive System Neoplasm

Professional guidelines

PubMed

Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Ciardiello F, Ciardiello D, Martini G, Napolitano S, Tabernero J, Cervantes A
CA Cancer J Clin 2022 Jul;72(4):372-401. Epub 2022 Apr 26 doi: 10.3322/caac.21728. PMID: 35472088
Biller LH, Schrag D
JAMA 2021 Feb 16;325(7):669-685. doi: 10.1001/jama.2021.0106. PMID: 33591350

Recent clinical studies

Etiology

Vosough P, Khatami SH, Hashemloo A, Tajbakhsh A, Karimi-Fard F, Taghvimi S, Taheri-Anganeh M, Soltani Fard E, Savardashtaki A, Movahedpour A
Clin Chim Acta 2023 Feb 1;540:117216. Epub 2022 Dec 30 doi: 10.1016/j.cca.2022.117216. PMID: 36592922
Alese OB, Cook N, Ortega-Franco A, Ulanja MB, Tan L, Tie J
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-20. doi: 10.1200/EDBK_349143. PMID: 35471832
Keung EZ, Raut CP, Rutkowski P
Ann Surg Oncol 2020 Oct;27(10):3659-3671. Epub 2020 Jul 30 doi: 10.1245/s10434-020-08869-w. PMID: 32734368Free PMC Article
Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG; GRID study investigators
Lancet 2013 Jan 26;381(9863):295-302. Epub 2012 Nov 22 doi: 10.1016/S0140-6736(12)61857-1. PMID: 23177515Free PMC Article
Albulescu R, Neagu M, Albulescu L, Tanase C
Expert Rev Mol Diagn 2011 Jan;11(1):101-20. doi: 10.1586/erm.10.106. PMID: 21171925

Diagnosis

Schaefer IM, DeMatteo RP, Serrano C
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-15. doi: 10.1200/EDBK_351231. PMID: 35522913Free PMC Article
Kelly CM, Gutierrez Sainz L, Chi P
J Hematol Oncol 2021 Jan 5;14(1):2. doi: 10.1186/s13045-020-01026-6. PMID: 33402214Free PMC Article
Grozinsky-Glasberg S, Alexandraki KI, Angelousi A, Chatzellis E, Sougioultzis S, Kaltsas G
Endocrinol Metab Clin North Am 2018 Sep;47(3):645-660. Epub 2018 Jul 11 doi: 10.1016/j.ecl.2018.04.013. PMID: 30098721
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

Janjigian YY, Van Cutsem E, Muro K, Wainberg Z, Al-Batran SE, Hyung WJ, Molena D, Marcovitz M, Ruscica D, Robbins SH, Negro A, Tabernero J
Future Oncol 2022 Jun;18(20):2465-2473. Epub 2022 May 10 doi: 10.2217/fon-2022-0093. PMID: 35535555
Schaefer IM, DeMatteo RP, Serrano C
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-15. doi: 10.1200/EDBK_351231. PMID: 35522913Free PMC Article
Cafri G, Gartner JJ, Zaks T, Hopson K, Levin N, Paria BC, Parkhurst MR, Yossef R, Lowery FJ, Jafferji MS, Prickett TD, Goff SL, McGowan CT, Seitter S, Shindorf ML, Parikh A, Chatani PD, Robbins PF, Rosenberg SA
J Clin Invest 2020 Nov 2;130(11):5976-5988. doi: 10.1172/JCI134915. PMID: 33016924Free PMC Article
Keung EZ, Raut CP, Rutkowski P
Ann Surg Oncol 2020 Oct;27(10):3659-3671. Epub 2020 Jul 30 doi: 10.1245/s10434-020-08869-w. PMID: 32734368Free PMC Article
Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG; GRID study investigators
Lancet 2013 Jan 26;381(9863):295-302. Epub 2012 Nov 22 doi: 10.1016/S0140-6736(12)61857-1. PMID: 23177515Free PMC Article

Prognosis

Biller LH, Schrag D
JAMA 2021 Feb 16;325(7):669-685. doi: 10.1001/jama.2021.0106. PMID: 33591350
Arnold M, Abnet CC, Neale RE, Vignat J, Giovannucci EL, McGlynn KA, Bray F
Gastroenterology 2020 Jul;159(1):335-349.e15. Epub 2020 Apr 2 doi: 10.1053/j.gastro.2020.02.068. PMID: 32247694Free PMC Article
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P, Gelderblom H, Hohenberger P, Leahy M, von Mehren M, Joensuu H, Badalamenti G, Blackstein M, Le Cesne A, Schöffski P, Maki RG, Bauer S, Nguyen BB, Xu J, Nishida T, Chung J, Kappeler C, Kuss I, Laurent D, Casali PG; GRID study investigators
Lancet 2013 Jan 26;381(9863):295-302. Epub 2012 Nov 22 doi: 10.1016/S0140-6736(12)61857-1. PMID: 23177515Free PMC Article
Pinchot SN, Holen K, Sippel RS, Chen H
Oncologist 2008 Dec;13(12):1255-69. Epub 2008 Dec 17 doi: 10.1634/theoncologist.2008-0207. PMID: 19091780Free PMC Article

Clinical prediction guides

Wang MX, Devine C, Segaran N, Ganeshan D
World J Gastroenterol 2021 Nov 7;27(41):7125-7133. doi: 10.3748/wjg.v27.i41.7125. PMID: 34887632Free PMC Article
Yonkus JA, Alva-Ruiz R, Grotz TE
Curr Treat Options Oncol 2021 Mar 20;22(5):37. doi: 10.1007/s11864-021-00837-0. PMID: 33743084
Turkes F, Mencel J, Starling N
J Gastroenterol 2020 Oct;55(10):909-926. Epub 2020 Aug 3 doi: 10.1007/s00535-020-01710-x. PMID: 32748171Free PMC Article
Zlobec I, Berger MD, Lugli A
Br J Cancer 2020 Sep;123(5):700-708. Epub 2020 Jun 30 doi: 10.1038/s41416-020-0954-z. PMID: 32601463Free PMC Article
Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH
Ann Surg 1999 Sep;230(3):309-18; discussion 318-21. doi: 10.1097/00000658-199909000-00004. PMID: 10493478Free PMC Article

Recent systematic reviews

Shah MA, Kennedy EB, Alarcon-Rozas AE, Alcindor T, Bartley AN, Malowany AB, Bhadkamkar NA, Deighton DC, Janjigian Y, Karippot A, Khan U, King DA, Klute K, Lacy J, Lee JJ, Mehta R, Mukherjee S, Nagarajan A, Park H, Saeed A, Semrad TJ, Shitara K, Smyth E, Uboha NV, Vincelli M, Wainberg Z, Rajdev L
J Clin Oncol 2023 Mar 1;41(7):1470-1491. Epub 2023 Jan 5 doi: 10.1200/JCO.22.02331. PMID: 36603169
Morris VK, Kennedy EB, Baxter NN, Benson AB 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C
J Clin Oncol 2023 Jan 20;41(3):678-700. Epub 2022 Oct 17 doi: 10.1200/JCO.22.01690. PMID: 36252154Free PMC Article
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z
Asian Pac J Cancer Prev 2018 Mar 27;19(3):591-603. doi: 10.22034/APJCP.2018.19.3.591. PMID: 29579788Free PMC Article

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